Leprot Gene Search Result

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3 records found for search term Leprot

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1353937	LEPROT	leptin receptor overlapping transcript	LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., ... (more) 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]	1	65420668	65436007	Human	74	symbol , COSMIC , description , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
1316198	LEPROTL1	leptin receptor overlapping transcript like 1	Enables identical protein binding activity. Predicted to be involved in late endosome to vacuole transport via multivesicular body sorting pathway and negative regulation of growth hormone receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in endosome. [provided ... (more) by Alliance of Genome Resources, Jul 2025]	8	30095408	30138348	Human	72	symbol , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
735832	LEPR	leptin receptor	The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regula ... (more) tion of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).[provided by RefSeq, Nov 2010]	1	65420652	65641559	Human	674	description	gene, protein-coding, REVIEWED [RefSeq]