Igfbp1 Gene Search Result

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2 records found for search term Igfbp1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
69038	IGFBP1	insulin like growth factor binding protein 1	This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGF ... (more) s) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients. [provided by RefSeq, Aug 2017]	7	45888488	45893660	Human	422	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
731720	CCN1	cellular communication network factor 1	The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apopto ... (more) sis, and extracellular matrix formation. [provided by RefSeq, Sep 2011]	1	85580761	85583950	Human	499	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]