E2f5 Gene Search Result

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3 records found for search term E2f5

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
731057	E2F5	E2F transcription factor 5	The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain sev ... (more) eral evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]	8	85177154	85214518	Human	147	symbol , old_gene_name , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
16562774	E2F5-DT	E2F5 divergent transcript		8	85172077	85177041	Human		symbol , old_gene_name , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
16560136	AC011773.1	novel transcript, antisense to E2F5					Human		name	gene, lncrna