E2F5-DT (E2F5 divergent transcript) - Rat Genome Database

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Gene: E2F5-DT (E2F5 divergent transcript) Homo sapiens
Analyze
Symbol: E2F5-DT
Name: E2F5 divergent transcript
RGD ID: 16562774
HGNC Page HGNC:55393
Description:
Type: ncrna (Ensembl: lncRNA)
RefSeq Status: VALIDATED
Previously known as: AC011773.4; LOC102723322; novel transcript, antisense to E2F5; uncharacterized LOC102723322
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38.p14 Ensembl - Human Genome Assembly GRCh38 Ensembl
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38885,172,077 - 85,177,041 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl885,172,077 - 85,177,062 (-)EnsemblGRCh38hg38GRCh38
GRCh37886,084,312 - 86,089,276 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map8q21.2NCBI
CHM1_1886,135,885 - 86,140,852 (-)NCBICHM1_1
T2T-CHM13v2.0885,610,676 - 85,615,641 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 8q21.11-21.2(chr8:73879385-85611466)x1 copy number loss See cases [RCV000054259] Chr8:73879385..85611466 [GRCh38]
Chr8:74791620..86523695 [GRCh37]
Chr8:74954174..86710947 [NCBI36]
Chr8:8q21.11-21.2		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145049449)x3 copy number gain See cases [RCV000051206] Chr8:241530..145049449 [GRCh38]
Chr8:191530..146274835 [GRCh37]
Chr8:181530..146245639 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:77480050-145068712)x3 copy number gain See cases [RCV000139036] Chr8:77480050..145068712 [GRCh38]
Chr8:78392286..146294098 [GRCh37]
Chr8:78554841..146264902 [NCBI36]
Chr8:8q21.13-24.3		 pathogenic
GRCh38/hg38 8q13.1-22.1(chr8:66171669-93505509)x3 copy number gain See cases [RCV000137050] Chr8:66171669..93505509 [GRCh38]
Chr8:67083904..94517737 [GRCh37]
Chr8:67246458..94586913 [NCBI36]
Chr8:8q13.1-22.1		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241605-145054781)x3 copy number gain See cases [RCV000138643] Chr8:241605..145054781 [GRCh38]
Chr8:191605..146280167 [GRCh37]
Chr8:181605..146250971 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:241530-145054634)x3 copy number gain See cases [RCV000053602] Chr8:241530..145054634 [GRCh38]
Chr8:191530..146280020 [GRCh37]
Chr8:181530..146250824 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8q11.1-24.3(chr8:46031340-139285494)x3 copy number gain See cases [RCV000139539] Chr8:46031340..139285494 [GRCh38]
Chr8:46942962..140297737 [GRCh37]
Chr8:47062127..140366919 [NCBI36]
Chr8:8q11.1-24.3		 pathogenic
GRCh38/hg38 8q21.2(chr8:84246857-85606287)x1 copy number loss See cases [RCV000136883] Chr8:84246857..85606287 [GRCh38]
Chr8:85159092..86518516 [GRCh37]
Chr8:85321647..86705768 [NCBI36]
Chr8:8q21.2		 uncertain significance
GRCh38/hg38 8p23.3-q24.3(chr8:208048-145070385)x3 copy number gain See cases [RCV000141808] Chr8:208048..145070385 [GRCh38]
Chr8:158048..146295771 [GRCh37]
Chr8:148048..146266575 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8q21.13-24.3(chr8:78614077-145054634)x3 copy number gain See cases [RCV000142597] Chr8:78614077..145054634 [GRCh38]
Chr8:79526312..146280020 [GRCh37]
Chr8:79688867..146250824 [NCBI36]
Chr8:8q21.13-24.3		 pathogenic
GRCh38/hg38 8p23.3-q24.3(chr8:226452-145068712)x3 copy number gain See cases [RCV000142858] Chr8:226452..145068712 [GRCh38]
Chr8:176452..146294098 [GRCh37]
Chr8:166452..146264902 [NCBI36]
Chr8:8p23.3-q24.3		 pathogenic
GRCh38/hg38 8p21.3-q24.3(chr8:21291522-145070385)x3 copy number gain See cases [RCV000142021] Chr8:21291522..145070385 [GRCh38]
Chr8:21149033..146295771 [GRCh37]
Chr8:21193313..146266575 [NCBI36]
Chr8:8p21.3-q24.3		 pathogenic
GRCh38/hg38 8q21.2-21.3(chr8:83721453-87866414)x3 copy number gain See cases [RCV000143246] Chr8:83721453..87866414 [GRCh38]
Chr8:84633688..88878642 [GRCh37]
Chr8:84796243..88947758 [NCBI36]
Chr8:8q21.2-21.3		 uncertain significance
GRCh38/hg38 8q21.13-21.3(chr8:77765431-91839285)x1 copy number loss See cases [RCV000054261] Chr8:77765431..91839285 [GRCh38]
Chr8:78677666..92851513 [GRCh37]
Chr8:78840221..92920689 [NCBI36]
Chr8:8q21.13-21.3		 pathogenic
GRCh38/hg38 8q21.13-22.1(chr8:78672463-95366868)x1 copy number loss See cases [RCV000054262] Chr8:78672463..95366868 [GRCh38]
Chr8:79584698..96379096 [GRCh37]
Chr8:79747253..96448272 [NCBI36]
Chr8:8q21.13-22.1		 pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:312
Count of miRNA genes:286
Interacting mature miRNAs:300
Transcripts:ENST00000562577, ENST00000566000
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium
Low 62 17 362 13 253 15 451 30 515 55 548 371 1 1 356
Below cutoff 1869 1746 1074 375 831 230 2231 1215 2944 310 787 991 154 601 1376 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000562577
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl885,172,077 - 85,177,041 (-)Ensembl
RefSeq Acc Id: ENST00000566000
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl885,175,799 - 85,177,062 (-)Ensembl
RefSeq Acc Id: NR_134311
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38885,172,077 - 85,177,041 (-)NCBI
T2T-CHM13v2.0885,610,676 - 85,615,641 (-)NCBI
Sequence:

Additional Information

Database Acc Id Source(s)
COSMIC E2F5-DT COSMIC
Ensembl Genes ENSG00000260493 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000562577 ENTREZGENE
GTEx ENSG00000260493 GTEx
HGNC ID HGNC:55393 ENTREZGENE
Human Proteome Map E2F5-DT Human Proteome Map
NCBI Gene LOC102723322 ENTREZGENE
RNAcentral URS0000A769AD RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-28 E2F5-DT  E2F5 divergent transcript  AC011773.4  novel transcript, antisense to E2F5  Symbol and/or name change 19259463 PROVISIONAL
2020-06-25 AC011773.4  novel transcript, antisense to E2F5  LOC102723322  uncharacterized LOC102723322  Symbol and/or name change 19259462 PROVISIONAL
2020-06-18 LOC102723322  uncharacterized LOC102723322  AC011773.4  novel transcript, antisense to E2F5  Symbol and/or name change 5135510 APPROVED