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Gene: E2F5 (E2F transcription factor 5) Homo sapiens
Symbol: E2F5
Name: E2F transcription factor 5
Description: Exhibits transcription factor binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; and regulation of cell cycle. Localizes to the fibrillar center and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E2F transcription factor 5, p130-binding; E2F-5; transcription factor E2F5
Mus musculus (house mouse) : E2f5 (E2F transcription factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : E2f5 (E2F transcription factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : E2f5 (E2F transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : E2F5 (E2F transcription factor 5)
Canis lupus familiaris (dog) : E2F5 (E2F transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : E2f5 (E2F transcription factor 5)
Sus scrofa (pig) : E2F5 (E2F transcription factor 5)
Chlorocebus sabaeus (green monkey) : E2F5 (E2F transcription factor 5)
Heterocephalus glaber (naked mole-rat) : E2f5 (E2F transcription factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl885,177,154 - 85,217,158 (+)Ensembl
GRCh38885,177,154 - 85,214,518 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37886,089,619 - 86,126,753 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,276,871 - 86,314,005 (+)NCBINCBI36hg18NCBI36
Build 34886,276,876 - 86,314,002NCBI
Celera882,094,939 - 82,131,798 (+)NCBI
Cytogenetic Map8q21.2NCBI
HuRef881,583,766 - 81,620,799 (+)NCBIHuRef
CHM1_1886,141,195 - 86,178,340 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on E2F5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731057
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.