Dut Gene Search Result

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15 records found for search term Dut

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1349758	DUT	deoxyuridine triphosphatase	This gene encodes an essential enzyme of nucleotide metabolism. The encoded protein forms a ubiquitous, homotetrameric enzyme that hydrolyzes dUTP to dUMP and pyrophosphate. This reaction serves two cellular purposes: providing a precursor (dUMP) for the synthesis of thymine nucleotides needed for D ... (more) NA replication, and limiting intracellular pools of dUTP. Elevated levels of dUTP lead to increased incorporation of uracil into DNA, which induces extensive excision repair mediated by uracil glycosylase. This repair process, resulting in the removal and reincorporation of dUTP, is self-defeating and leads to DNA fragmentation and cell death. Alternative splicing of this gene leads to different isoforms that localize to either the mitochondrion or nucleus. A related pseudogene is located on chromosome 19. [provided by RefSeq, Jul 2008]	15	48331095	48343373	Human	251	symbol , old_gene_name , COSMIC , description , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
38645763	DUT-AS1	DUT antisense RNA 1	ASSOCIATED WITH Growth Mental Deficiency Syndrome of Myhre	15	48310468	48331856	Human	1	symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]
38609546	LOC441862	DUT pseudogene		19	52451206	52452288	Human		name	gene, pseudo, INFERRED [RefSeq]
16562235	AC023355.1	novel transcript, antisense to DUT					Human		name	gene, lncrna
16565823	AC009027.1	deoxyuridine triphosphatase (DUT) pseudogene					Human		name	gene, processed_pseudogene
5131596	DUTP1	deoxyuridine triphosphatase pseudogene 1		3	125310863	125311497	Human		symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
6481453	DUTP2	deoxyuridine triphosphatase pseudogene 2		8	123352307	123352645	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
5686985	DUTP3	deoxyuridine triphosphatase pseudogene 3		7	147146272	147146760	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
6481457	DUTP4	deoxyuridine triphosphatase pseudogene 4		X	149817172	149817648	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
6481456	DUTP5	deoxyuridine triphosphatase pseudogene 5		6	85426602	85427193	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
6481458	DUTP6	deoxyuridine triphosphatase pseudogene 6		1	166868734	166869207	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
6481460	DUTP7	deoxyuridine triphosphatase pseudogene 7		4	51865053	51865535	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
6481381	DUTP8	deoxyuridine triphosphatase pseudogene 8		4	98048499	98049112	Human		symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]
735617	ROBO1	roundabout guidance receptor 1	Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immu ... (more) noglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]	3	78597239	79767998	Human	379	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
16567992	LINC03106	long intergenic non-protein coding RNA 3106	Predicted to enable dUTP diphosphatase activity and magnesium ion binding activity. Predicted to be involved in dUMP biosynthetic process and dUTP catabolic process. [provided by Alliance of Genome Resources, Jul 2025]	9	26066675	26118408	Human	5	description	gene, ncrna, VALIDATED [RefSeq]