Dcn Gene Search Result

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9 records found for search term Dcn

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1346102	DCN	decorin	This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fi ... (more) bril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]	12	91140484	91182817	Human	344	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1605576	DCANP1	dendritic cell associated nuclear protein 1	This intronless gene is specifically expressed in dendritic cells (DCs), which are potent antigen-presenting cells involved in activating naive T cells to initiate antigen-specific immune response. The encoded protein is localized mainly in the perinucleus. One of the alleles (A/T) of this gene, tha ... (more) t causes premature translation termination at aa 117, has been associated with an increased prevalence of major depression in humans. [provided by RefSeq, Jul 2008]	5	135444214	135447348	Human	33	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1602219	DCUN1D1	defective in cullin neddylation 1 domain containing 1	Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation and regulation of protein ubiquitination. Located in cytosol and nucleoplasm. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Jul 2025]	3	182938074	182985918	Human	92	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1323358	DCUN1D2	defective in cullin neddylation 1 domain containing 2	Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]	13	113455819	113491563	Human	63	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1602987	DCUN1D3	defective in cullin neddylation 1 domain containing 3	Enables cullin family protein binding activity. Involved in several processes, including negative regulation of G1/S transition of mitotic cell cycle; regulation of protein neddylation; and response to UV-C. Located in several cellular components, including cytosol; nucleoplasm; and perinuclear regi ... (more) on of cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]	16	20854925	20900358	Human	106	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1604387	DCUN1D4	defective in cullin neddylation 1 domain containing 4	Enables cullin family protein binding activity. Involved in positive regulation of protein neddylation. Located in nucleus. [provided by Alliance of Genome Resources, Jul 2025]	4	51833884	51916837	Human	111	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1601949	DCUN1D5	defective in cullin neddylation 1 domain containing 5	Enables cullin family protein binding activity. Involved in DNA damage response; positive regulation of protein neddylation; and regulation of cell growth. Located in nucleus and spindle. [provided by Alliance of Genome Resources, Jul 2025]	11	103050686	103092160	Human	81	old_gene_name , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
16552011	AC104117.1	DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae) (DCUN1D3) pseudogene					Human		name	gene, processed_pseudogene
16556754	AL353718.1	pseudogene similar to part of DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) DCUN1D1					Human		name	gene, processed_pseudogene