Creb3 Gene Search Result

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7 records found for search term Creb3

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1318829	CREB3	cAMP responsive element binding protein 3	This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) ... (more) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.[provided by RefSeq, Nov 2009]	9	35732666	35736999	Human	175	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1347233	CREB3L4	cAMP responsive element binding protein 3 like 4	This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including pr ... (more) otein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]	1	153967487	153974359	Human	98	symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
1603892	CREBRF	CREB3 regulatory factor	Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of endoplasmic reticulum unfolded protein response; positive reg ... (more) ulation of protein catabolic process; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Jul 2025]	5	173056352	173139284	Human	164	old_gene_name , name	gene, protein-coding, VALIDATED [RefSeq]
1342471	CREB3L1	cAMP responsive element binding protein 3 like 1	The protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target ge ... (more) nes by binding to box-B elements. [provided by RefSeq, Jun 2013]	11	46277662	46321409	Human	271	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1314429	CREB3L2	cAMP responsive element binding protein 3 like 2	This gene encodes a member of the oasis bZIP transcription factor family. Members of this family can dimerize but form homodimers only. The encoded protein is a transcriptional activator. Translocations between this gene on chromosome 7 and the gene fused in sarcoma on chromosome 16 can be found in ... (more) some tumors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]	7	137874979	138002086	Human	154	symbol , COSMIC , Human Proteome Map	gene, protein-coding, VALIDATED [RefSeq]
1317760	CREB3L3	cAMP responsive element binding protein 3 like 3	This gene encodes a member of the basic-leucine zipper family and the AMP-dependent transcription factor family. The encoded protein is localized to the endoplasmic reticulum and acts as a transcription factor activated by cyclic AMP stimulation. The encoded protein binds the cyclic AMP response ele ... (more) ment (CRE) and the box-B element and has been linked to acute inflammatory response, hepatocellular carcinoma, triglyceride metabolism, and hepcidin expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]	19	4153631	4173054	Human	184	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
14402099	CREB3L2-AS1	CREB3L2 antisense RNA 1		7	137953348	137957966	Human		symbol , COSMIC , name , Human Proteome Map	gene, ncrna, VALIDATED [RefSeq]