| 621274 | Xpnpep1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity; manganese ion binding (ortholog); metalloaminopeptidase activity (ortholog); INVOLVED IN proteolysis; bradykinin catabolic process (ortholog); negative regulation of programmed cell death (ortholog); PARTICIPATES IN kallikrein-kinin cascade pa thway; FOUND IN cytoplasm; cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 1 | 262006761 | 262057479 | Rat | 117 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 733430 | XPNPEP1 | X-prolyl aminopeptidase 1 | This gene encodes the cytosolic form of a metalloaminopeptidase that catalyzes the cleavage of the N-terminal amino acid adjacent to a proline residue. The gene product may play a role in degradation and maturation of tachykinins, neuropeptides, and peptide hormones. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Nov 2009] | 10 | 109864766 | 109923511 | Human | 114 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 733431 | Xpnpep1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | Predicted to enable manganese ion binding activity; metalloaminopeptidase activity; and protein homodimerization activity. Predicted to be involved in bradykinin catabolic process; negative regulation of programmed cell death; and proteolysis. Predicted to be located in cytoplasm. Predicted to be ac tive in cytosol. Orthologous to human XPNPEP1 (X-prolyl aminopeptidase 1). [provided by Alliance of Genome Resources, Apr 2025] | 19 | 52919710 | 53027093 | Mouse | 170 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9043291 | Xpnpep1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (ortholog); manganese ion binding (ortholog); metalloaminopeptidase activity (ortholog); INVOLVED IN bradykinin catabolic process (ortholog); negative regulation of programmed cell death (ortholog); proteolysis (ortholog); PARTICIPATES IN kalli krein-kinin cascade pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog) | NW_004955485 | 1436834 | 1501408 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11974882 | XPNPEP1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); manganese ion binding (inferred); INVOLVED IN bradykinin catabolic process (inferred); negative regulation of programmed cell death (inferred); proteolysis (inferred); PARTICIPATES IN kallikrein-kinin cascade pathway; FOUND IN cytosol (ortholog) | 10 | 106457390 | 106516111 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12417780 | XPNPEP1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); manganese ion binding (inferred); INVOLVED IN bradykinin catabolic process (inferred); negative regulation of programmed cell death (inferred); proteolysis (inferred); PARTICIPATES IN kallikrein-kinin cascade pathway; FOUND IN cytosol (ortholog) | 28 | 21267588 | 21322044 | Dog | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12585117 | Xpnpep1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); manganese ion binding (inferred); INVOLVED IN bradykinin catabolic process (inferred); negative regulation of programmed cell death (inferred); proteolysis (inferred); PARTICIPATES IN kallikrein-kinin cascade pathway; FOUND IN cytosol (ortholog) | NW_004936486 | 801563 | 853107 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626175185 | xpnpep1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18904333 | Xpnpep1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits manganese ion binding (ortholog); protein homodimerization activity (ortholog); INVOLVED IN bradykinin catabolic process (ortholog); negative regulation of programmed cell death (ortholog); PARTICIPATES IN kallikrein-kinin cascade pathway; FOUND IN cytosol (ortholog) | | | | Naked Mole-Rat | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626173242 | xpnpep1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626187529 | xpnpep1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626188704 | xpnpep1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14274659 | XPNPEP1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); manganese ion binding (inferred); INVOLVED IN bradykinin catabolic process (inferred); negative regulation of programmed cell death (inferred); proteolysis (inferred); PARTICIPATES IN kallikrein-kinin cascade pathway; FOUND IN cytosol (ortholog) | | | | Pig | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626087911 | Xpnpep1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (ortholog); manganese ion binding (ortholog); metalloaminopeptidase activity (ortholog); INVOLVED IN bradykinin catabolic process (ortholog); negative regulation of programmed cell death (ortholog); proteolysis (ortholog); PARTICIPATES IN kalli krein-kinin cascade pathway; FOUND IN cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18699893 | XPNPEP1 | X-prolyl aminopeptidase 1 | ENCODES a protein that exhibits aminopeptidase activity (inferred); hydrolase activity (inferred); manganese ion binding (inferred); INVOLVED IN bradykinin catabolic process (inferred); negative regulation of programmed cell death (inferred); proteolysis (inferred); PARTICIPATES IN kallikrein-kinin cascade pathway; FOUND IN cytosol (ortholog) | | | | Green Monkey | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |