| 628850 | Wnt5b | Wnt family member 5B | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN chondrocyte differentiation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canoni cal pathway; basal cell carcinoma pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); leiomyoma (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 154281852 | 154406081 | Rat | 142 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1346792 | WNT5B | Wnt family member 5B | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008] | 12 | 1617056 | 1647212 | Human | 159 | symbol , COSMIC , description , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1551592 | Wnt5b | wingless-type MMTV integration site family, member 5B | Enables signaling receptor binding activity. Acts upstream of or within negative regulation of canonical Wnt signaling pathway and positive regulation of fat cell differentiation. Located in cell surface and extracellular matrix. Is expressed in several structures, including alimentary system; centr al nervous system; genitourinary system; limb; and sensory organ. Orthologous to human WNT5B (Wnt family member 5B). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 119409493 | 119521847 | Mouse | 159 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8899639 | Wnt5b | Wnt family member 5B | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN chondrocyte differentiation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canoni cal pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); leiomyoma (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog) | NW_004955454 | 4158648 | 4192709 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11697801 | WNT5B | Wnt family member 5B | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of fat cell differentiation (ortholog); PARTICIPATES IN Wnt signaling p athway; Wnt signaling, canonical pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); leiomyoma (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | 12 | 1633987 | 1757431 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12053764 | WNT5B | Wnt family member 5B | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of fat cell differentiation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH a denoid cystic carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); leiomyoma (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | 27 | 43662482 | 43679713 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12692116 | Wnt5b | Wnt family member 5B | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of fat cell differentiation (ortholog); PARTICIPATES IN Wnt signaling p athway; Wnt signaling, canonical pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); leiomyoma (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | NW_004936606 | 1741500 | 1854857 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18551351 | WNT5B | Wnt family member 5B | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of fat cell differentiation (ortholog); PARTICIPATES IN Wnt signaling p athway; Wnt signaling, canonical pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); leiomyoma (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625954640 | Wnt5b | Wnt family member 5B | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN chondrocyte differentiation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of cell migration (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canoni cal pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); leiomyoma (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14118524 | WNT5B | Wnt family member 5B | ENCODES a protein that exhibits signaling receptor binding (inferred); INVOLVED IN negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of fat cell differentiation (ortholog); PARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH a denoid cystic carcinoma (ortholog); leiomyoma (ortholog); Salivary Gland Neoplasms (ortholog); FOUND IN cell surface (inferred); extracellular matrix (inferred); extracellular region (inferred); INTERACTS WITH ethanol | | | | Pig | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18933282 | Wnt5b | Wnt family member 5B | ENCODES a protein that exhibits cytokine activity (inferred); frizzled binding (inferred); signaling receptor binding (inferred); INVOLVED IN chondrocyte differentiation (ortholog); negative regulation of canonical Wnt signaling pathway (ortholog); positive regulation of cell migration (ortholog); P ARTICIPATES IN Wnt signaling pathway; Wnt signaling, canonical pathway; ASSOCIATED WITH adenoid cystic carcinoma (ortholog); Experimental Mammary Neoplasms (ortholog); leiomyoma (ortholog); FOUND IN cell surface (ortholog); extracellular matrix (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237929 | wnt5b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155237156 | wnt5b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258392 | wnt5b.S | | | | | | African Clawed Frog | | symbol | gene, null |