| 621369 | Uox | urate oxidase | ENCODES a protein that exhibits urate oxidase activity; INVOLVED IN urate catabolic process; PARTICIPATES IN caffeine metabolic pathway; purine metabolic pathway; ASSOCIATED WITH increased blood urea nitrogen level; increased blood uric acid level; tubulointerstitial nephritis; ASSOCIATED WITH hyper uricemia; FOUND IN peroxisome; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate | 2 | 238147130 | 238183320 | Rat | 82 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 732386 | Uox | urate oxidase | Enables urate oxidase activity. Involved in several processes, including allantoin metabolic process; nucleobase-containing small molecule metabolic process; and urate catabolic process. Located in mitochondrion. Is active in peroxisome. Is expressed in several structures, including alimentary syste m; genitourinary system; integumental system; respiratory system; and sensory organ. Used to study hyperuricemia; kidney disease; and nephrogenic diabetes insipidus. Orthologous to human UOX (urate oxidase (pseudogene)). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 146302904 | 146337238 | Mouse | 158 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1343488 | UOX | urate oxidase (pseudogene) | Urate oxidase is an enzyme that catalyzes the oxidation of uric acid to allantoin. This gene has been inactivated by mutation and is nonfunctional in humans and some other primates. [provided by RefSeq, Jul 2008] | 1 | 84364958 | 84384801 | Human | 62 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, VALIDATED [RefSeq] |
| 12408175 | UOX | urate oxidase | ENCODES a protein that exhibits oxidoreductase activity (inferred); urate oxidase activity (inferred); INVOLVED IN adenosine catabolic process (inferred); AMP catabolic process (inferred); dAMP catabolic process (inferred); ASSOCIATED WITH acute kidney failure (ortholog); hyperuricemia (ortholog); n ephrogenic diabetes insipidus (ortholog); FOUND IN peroxisome (inferred) | 6 | 63482384 | 63513538 | Dog | 35 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 13876724 | UOX | urate oxidase | ENCODES a protein that exhibits oxidoreductase activity (inferred); urate oxidase activity (inferred); INVOLVED IN adenosine catabolic process (inferred); AMP catabolic process (inferred); dAMP catabolic process (inferred); FOUND IN peroxisome (inferred) | | | | Pig | 29 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 288057087 | uox | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 150521540 | Uoxem1Cya | urate oxidase; CRISPR/Cas9 induced mutant1, Cya | ASSOCIATED WITH increased blood urea nitrogen level; increased blood uric acid level; tubulointerstitial nephritis; ASSOCIATED WITH hyperuricemia | | | | Rat | 4 | symbol | gene, allele |
| 70901 | Dnase2b | deoxyribonuclease 2 beta | ENCODES a protein that exhibits deoxyribonuclease II activity; DNA endonuclease activity (ortholog); INVOLVED IN apoptotic DNA fragmentation (inferred); DNA metabolic process (inferred); ASSOCIATED WITH cataract (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); INTERACTS WI TH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 2 | 238131182 | 238168041 | Rat | 69 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1605730 | HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II m olecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008] | 6 | 33064569 | 33080748 | Human | 218 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
| 1347423 | HLA-G | major histocompatibility complex, class I, G | HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008] | 6 | 29826474 | 29831021 | Human | 244 | GenBank Protein | gene, protein-coding, REVIEWED [RefSeq] |
