| 1308273 | Ubqln4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of autophagosome maturati on (ortholog); negative regulation of double-strand break repair via homologous recombination (ortholog); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 4-amino-2,6-dinitrotoluene; bisphenol A | 2 | 176310524 | 176325724 | Rat | 105 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1344813 | UBQLN4 | ubiquilin 4 | Enables K48-linked polyubiquitin modification-dependent protein binding activity and identical protein binding activity. Involved in DNA damage response; negative regulation of double-strand break repair via homologous recombination; and regulation of catabolic process. Located in several cellular c omponents, including autophagosome; proteasome complex; and site of DNA damage. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025] | 1 | 156031247 | 156053798 | Human | 103 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1550028 | Ubqln4 | ubiquilin 4 | Predicted to enable K48-linked polyubiquitin modification-dependent protein binding activity and identical protein binding activity. Predicted to be involved in several processes, including negative regulation of double-strand break repair via homologous recombination; regulation of catabolic proces s; and ubiquitin-dependent protein catabolic process. Located in cytosol and endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Orthologous to human UBQLN4 (ubiquilin 4). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 88460984 | 88477032 | Mouse | 143 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9019469 | Ubqln4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of autophagosome maturati on (ortholog); negative regulation of double-strand break repair via homologous recombination (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955545 | 2218794 | 2236665 | Chinchilla | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11953077 | UBQLN4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (inferred); K48-linked polyubiquitin modification-dependent protein binding (inferred); polyubiquitin modification-dependent protein binding (inferred); INVOLVED IN autophagy (inferred); cellular response to stress (inferred); DNA damage resp onse (inferred); FOUND IN autophagosome (inferred); chromosome (inferred); cytoplasm (inferred) | 1 | 131374635 | 131395986 | Bonobo | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12145611 | UBQLN4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (inferred); K48-linked polyubiquitin modification-dependent protein binding (inferred); polyubiquitin modification-dependent protein binding (inferred); INVOLVED IN autophagy (inferred); DNA damage response (inferred); DNA repair (inferred); FOUND IN autophagosome (inferred); chromosome (inferred); cytoplasm (inferred) | 7 | 41764209 | 41778457 | Dog | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12461928 | Ubqln4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (inferred); K48-linked polyubiquitin modification-dependent protein binding (inferred); polyubiquitin modification-dependent protein binding (inferred); INVOLVED IN autophagy (inferred); DNA damage response (inferred); DNA repair (inferred); FOUND IN autophagosome (inferred); chromosome (inferred); cytoplasm (inferred) | NW_004936580 | 5299864 | 5316583 | Squirrel | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155243533 | ubqln4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 20865793 | UBQLN4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (inferred); K48-linked polyubiquitin modification-dependent protein binding (inferred); polyubiquitin modification-dependent protein binding (inferred); INVOLVED IN cellular response to stress (inferred); DNA damage response (inferred); negat ive regulation of autophagosome maturation (inferred); FOUND IN autophagosome (inferred); cytoplasm (inferred); cytosol (inferred) | | | | Green Monkey | 21 | symbol | gene, protein-coding |
| 626119042 | Ubqln4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of autophagosome maturati on (ortholog); negative regulation of double-strand break repair via homologous recombination (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18587841 | UBQLN4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN DNA damage response (ortholog); negative regulation of autophagosome maturati on (ortholog); negative regulation of double-strand break repair via homologous recombination (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Green Monkey | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18907779 | Ubqln4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (ortholog); K48-linked polyubiquitin modification-dependent protein binding (ortholog); INVOLVED IN negative regulation of autophagosome maturation (ortholog); negative regulation of double-strand break repair via homologous recombination (or tholog); regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog); FOUND IN cytoplasm (ortholog); cytosolic proteasome complex (ortholog); endoplasmic reticulum membrane (ortholog) | | | | Naked Mole-Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14250151 | UBQLN4 | ubiquilin 4 | ENCODES a protein that exhibits identical protein binding (inferred); K48-linked polyubiquitin modification-dependent protein binding (inferred); polyubiquitin modification-dependent protein binding (inferred); INVOLVED IN autophagy (inferred); DNA damage response (inferred); DNA repair (inferred); FOUND IN autophagosome (inferred); chromosome (inferred); cytoplasm (inferred) | | | | Pig | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231779 | ubqln4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236144 | ubqln4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 2299109 | Ubqln4Tn(sb-T2/Bart3)2.230Mcwi | ubiquilin 4; transposon insertion 2.230, Medical College of Wisconsin | this mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 4th intron of the Ubqln4 gene | | | | Rat | | symbol , description , old_gene_symbol | gene, allele |
| 1344129 | UBQLN4P1 | ubiquilin 4 pseudogene 1 | | 3 | 148984184 | 148987750 | Human | | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, pseudo, INFERRED [RefSeq] |
| 4107116 | UBQLN4P2 | ubiquilin 4 pseudogene 2 | | 2 | 152876744 | 152878730 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |