| 1303284 | Trpa1 | transient receptor potential cation channel, subfamily A, member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity; voltage-gated calcium channel activity; calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol; cellular response to caffeine; cellular response to carbon dioxide; ASSOCIATE D WITH Abdominal Pain; asthma; Cold Hypersensitivity; FOUND IN apical plasma membrane; axon; plasma membrane (ortholog); INTERACTS WITH 3-phenylprop-2-enal; 4-hydroxynon-2-enal; aconitine | 5 | 9163060 | 9217325 | Rat | 320 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1344231 | TRPA1 | transient receptor potential cation channel subfamily A member 1 | The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provid ed by RefSeq, Jul 2008] | 8 | 72021250 | 72090010 | Human | 320 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1553598 | Trpa1 | transient receptor potential cation channel, subfamily A, member 1 | Enables calcium channel activity. Involved in several processes, including cellular response to food; detection of mechanical stimulus involved in sensory perception; and intracellular calcium ion homeostasis. Acts upstream of or within several processes, including detection of stimulus involved in sensory perception of pain; response to hydrogen peroxide; and thermoception. Located in stereocilium bundle. Is active in plasma membrane. Is expressed in cochlea; dorsal root ganglion; glossopharyngeal ganglion; and lumbar dorsal root ganglion. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 14942868 | 14989086 | Mouse | 364 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9053819 | Trpa1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits calcium channel activity (ortholog); channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transmembrane transport (ortholog); calcium ion transport (ortholog); ASSOCIATED W ITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); plasma membrane (ortholog) | NW_004955444 | 7876284 | 7922010 | Chinchilla | 72 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11777195 | TRPA1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOC IATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog) | 8 | 68551685 | 68605336 | Bonobo | 88 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12365445 | TRPA1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOC IATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog) | 29 | 20951736 | 21000956 | Dog | 87 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12561715 | Trpa1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOC IATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog) | NW_004936648 | 1094460 | 1141394 | Squirrel | 85 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13899854 | TRPA1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOC IATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog) | | | | Pig | 88 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625835197 | Trpa1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits calcium channel activity (ortholog); channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transmembrane transport (ortholog); calcium ion transport (ortholog); ASSOCIATED W ITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); plasma membrane (ortholog) | | | | Black Rat | 72 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14388840 | TrpA1 | | | | | | Fly | | symbol | gene, null |
| 18908809 | Trpa1 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits channel activity (ortholog); identical protein binding (ortholog); intracellularly gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cell surface receptor signaling pathwa y (ortholog); ASSOCIATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog); plasma membrane (ortholog) | | | | Naked Mole-Rat | 82 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231312 | trpa1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155254829 | trpa1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155231311 | trpa1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 127285812 | Trpa1em1Gne | transient receptor potential cation channel, subfamily A, member 1;CRISPR/Cas9 induced mutant 1, Gne | ASSOCIATED WITH asthma | | | | Rat | 1 | symbol , description | gene, allele |
| 38676449 | Trpa1em1Kcrd | transient receptor potential cation channel, subfamily A, member 1; ZFN induced mutant 1, Kcrd | This Trpa1-deleted Wistar (background: Crl:WI) strain was generated by using Zinc Finger Nuclease at Kirin Company, Limited in 2013. Exon 22-24, which form ion channel pore required for the activation in Trpa1 gene, was dele ted. | | | | Rat | | symbol , description | gene, allele |
| 18556646 | LOC103236955 | transient receptor potential cation channel subfamily A member 1 | ENCODES a protein that exhibits osmolarity-sensing monoatomic cation channel activity (ortholog); voltage-gated calcium channel activity (ortholog); INVOLVED IN calcium ion transmembrane import into cytosol (ortholog); calcium ion transport (ortholog); cellular response to caffeine (ortholog); ASSOC IATED WITH Abdominal Pain (ortholog); asthma (ortholog); Bronchial Hyperreactivity (ortholog); FOUND IN apical plasma membrane (ortholog); axon (ortholog) | | | | Green Monkey | 88 | old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 16559079 | AC022905.1 | transient receptor potential cation channel, subfamily A, member 1 (TRPA1) pseudogene | | | | | Human | | name | gene, unprocessed_pseudogene |