| 631329 | Tnfrsf12a | TNF receptor superfamily member 12A | INVOLVED IN positive regulation of collagen biosynthetic process; cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH Pulmonary Arterial Hypertension; acute kidney failure (ortholog); Experimental Liver Cirr hosis (ortholog); FOUND IN cell surface (ortholog); plasma membrane (ortholog); ruffle (ortholog); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate | 10 | 13211670 | 13213666 | Rat | 312 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1343569 | TNFRSF12A | TNF receptor superfamily member 12A | Involved in positive regulation of extrinsic apoptotic signaling pathway and regulation of wound healing. Predicted to be located in cell surface and ruffle. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025] | 16 | 3020368 | 3022383 | Human | 320 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1550230 | Tnfrsf12a | tumor necrosis factor receptor superfamily, member 12a | Involved in regulation of angiogenesis. Acts upstream of or within extrinsic apoptotic signaling pathway; positive regulation of axon extension; and substrate-dependent cell migration, cell attachment to substrate. Located in cell surface; plasma membrane; and ruffle. Is expressed in several structu res, including adrenal medulla; alimentary system; genitourinary system; heart; and limb long bone. Orthologous to human TNFRSF12A (TNF receptor superfamily member 12A). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 23894419 | 23896423 | Mouse | 321 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8790459 | Tnfrsf12a | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (ortholog); p lasma membrane (ortholog); ruffle (ortholog) | NW_004955442 | 14320159 | 14322146 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11828681 | TNFRSF12A | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of axon extension (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (ortholog); ruff le (ortholog) | 16 | 1962179 | 1964223 | Bonobo | 29 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12077205 | TNFRSF12A | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of axon extension (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (inferred); memb rane (inferred); plasma membrane (inferred) | 6 | 38166160 | 38168189 | Dog | 32 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12602378 | Tnfrsf12a | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of axon extension (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (inferred); memb rane (inferred); plasma membrane (inferred) | NW_004936694 | 1149169 | 1151098 | Squirrel | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288056962 | tnfrsf12a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14276635 | TNFRSF12A | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of axon extension (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (inferred); memb rane (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol; dichlorine | | | | Pig | 34 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 18764780 | TNFRSF12A | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of axon extension (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (inferred); memb rane (inferred); plasma membrane (inferred) | | | | Green Monkey | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626034996 | Tnfrsf12a | TNF receptor superfamily member 12A | INVOLVED IN cell adhesion (ortholog); extrinsic apoptotic signaling pathway (ortholog); positive regulation of apoptotic process (ortholog); ASSOCIATED WITH acute kidney failure (ortholog); Experimental Liver Cirrhosis (ortholog); myocardial infarction (ortholog); FOUND IN cell surface (ortholog); p lasma membrane (ortholog); ruffle (ortholog) | | | | Black Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 284201366 | tnfrsf12a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 288056963 | tnfrsf12a.S | | | | | | African Clawed Frog | | symbol | gene, null |