| 1307901 | Tmem38a | transmembrane protein 38a | ENCODES a protein that exhibits identical protein binding (ortholog); potassium channel activity (ortholog); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN nuclear membrane (ortholog); sarcoplasmic reticulum (ortholog); sarcoplasmic reticulum membrane (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aconitine | 16 | 17292215 | 17307704 | Rat | 93 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1351909 | TMEM38A | transmembrane protein 38A | Predicted to enable potassium channel activity. Predicted to be involved in regulation of release of sequestered calcium ion into cytosol. Predicted to act upstream of or within several processes, including cellular response to caffeine; monoatomic cation transmembrane transport; and regulation of c ardiac muscle contraction by regulation of the release of sequestered calcium ion. Located in extracellular exosome. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 16661139 | 16690023 | Human | 97 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1550335 | Tmem38a | transmembrane protein 38A | Enables identical protein binding activity and potassium channel activity. Acts upstream of or within several processes, including cellular response to caffeine; monoatomic cation transmembrane transport; and regulation of cardiac muscle contraction by regulation of the release of sequestered calciu m ion. Located in nuclear membrane and sarcoplasmic reticulum. Is expressed in head mesenchyme; tongue; and vertebral axis musculature. Orthologous to human TMEM38A (transmembrane protein 38A). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 73325033 | 73341128 | Mouse | 100 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8855809 | Tmem38a | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (ortholog); potassium channel activity (ortholog); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN nuclear membrane (ortholog); sarcoplasmic reticulum (ortholog) | NW_004955524 | 1132111 | 1144335 | Chinchilla | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12000796 | TMEM38A | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN membrane (inferred); nuclear membrane (inferred); sarcoplasmic reticulum (inferred) | 19 | 16150715 | 16179256 | Bonobo | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12173302 | TMEM38A | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN membrane (inferred); nuclear membrane (inferred); sarcoplasmic reticulum (inferred) | 20 | 45876642 | 45895054 | Dog | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12487337 | Tmem38a | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN membrane (inferred); nuclear membrane (inferred); sarcoplasmic reticulum (inferred) | NW_004936596 | 3965220 | 3984120 | Squirrel | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14106754 | TMEM38A | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN membrane (inferred); nuclear membrane (inferred); sarcoplasmic reticulum (inferred) | | | | Pig | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18468060 | TMEM38A | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN membrane (inferred); nuclear membrane (inferred); sarcoplasmic reticulum (inferred) | | | | Green Monkey | 22 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239023 | tmem38a | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18926060 | Tmem38a | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (inferred); potassium channel activity (inferred); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN sarcoplasmic reticulum (ortholog) | | | | Naked Mole-Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625854487 | Tmem38a | transmembrane protein 38A | ENCODES a protein that exhibits identical protein binding (ortholog); potassium channel activity (ortholog); INVOLVED IN cellular response to caffeine (ortholog); endoplasmic reticulum organization (ortholog); potassium ion transmembrane transport (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOU ND IN nuclear membrane (ortholog); sarcoplasmic reticulum (ortholog) | | | | Black Rat | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155237409 | tmem38a.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241087 | tmem38a.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16561418 | AC091516.1 | transmembrane protein 38A (TMEM38A) | | 12 | 88057800 | 88058576 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 16565178 | AC008737.2 | transmembrane protein 38A (TMEM38A) pseudogene | | | | | Human | | name | gene, processed_pseudogene |