Tlk2 Gene Search Result

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17 records found for search term Tlk2

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1310907	Tlk2	tousled-like kinase 2	ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to gamma radiation (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); ASSOCIATED WITH autistic ... (more) disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental Disease (ortholog); FOUND IN intermediate filament (ortholog); nucleolus (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene	10	90648623	90748427	Rat	127	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
1322082	TLK2	tousled like kinase 2	This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with dou ... (more) ble-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]	17	62470914	62615481	Human	211	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1322083	Tlk2	tousled-like kinase 2 (Arabidopsis)	Predicted to enable ATP binding activity; identical protein binding activity; and protein serine/threonine kinase activity. Predicted to be involved in several processes, including cellular response to gamma radiation; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ... (more) and peptidyl-serine phosphorylation. Located in intermediate filament; nucleus; and perinuclear region of cytoplasm. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 57. Orthologous to human TLK2 (tousled like kinase 2). [provided by Alliance of Genome Resources, Apr 2025]	11	105066869	105174785	Mouse	169	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8894513	Tlk2	tousled like kinase 2	ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to gamma radiation (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); ASSOCIATED WITH autistic ... (more) disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental Disease (ortholog); FOUND IN intermediate filament (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog)	NW_004955478	9100863	9229448	Chinchilla	34	symbol	gene, protein-coding, MODEL [RefSeq]
11874784	TLK2	tousled like kinase 2	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental ... (more) Disease (ortholog); FOUND IN intermediate filament (inferred); nucleolus (inferred); nucleoplasm (inferred)	17	56542670	56678294	Bonobo	52	symbol	gene, protein-coding, MODEL [RefSeq]
12257063	TLK2	tousled like kinase 2	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental ... (more) Disease (ortholog); FOUND IN intermediate filament (inferred); nucleolus (inferred); nucleoplasm (inferred)	9	10686424	10804885	Dog	50	symbol	gene, protein-coding, MODEL [RefSeq]
12466912	Tlk2	tousled like kinase 2	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental ... (more) Disease (ortholog); FOUND IN intermediate filament (inferred); nucleolus (inferred); nucleoplasm (inferred)	NW_004936541	3303563	3422093	Squirrel	50	symbol	gene, protein-coding, MODEL [RefSeq]
155245797	tlk2						Tropical Clawed Frog		symbol	gene, null
626140915	Tlk2	tousled like kinase 2	ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN cellular response to gamma radiation (ortholog); chromosome segregation (ortholog); DNA damage response (ortholog); ASSOCIATED WITH autistic ... (more) disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental Disease (ortholog); FOUND IN intermediate filament (ortholog); nucleus (ortholog); perinuclear region of cytoplasm (ortholog)				Black Rat	34	symbol	gene, protein-coding, MODEL [RefSeq]
18924131	Tlk2	tousled like kinase 2	ENCODES a protein that exhibits identical protein binding (ortholog); transmembrane transporter binding (ortholog); INVOLVED IN cellular response to gamma radiation (ortholog); DNA damage response (ortholog); negative regulation of proteasomal ubiquitin-dependent protein catabolic process (ortholog) ... (more) ; ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental Disease (ortholog); FOUND IN intermediate filament (ortholog)				Naked Mole-Rat	43	symbol	gene, protein-coding, MODEL [RefSeq]
14272394	TLK2	tousled like kinase 2	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental ... (more) Disease (ortholog); FOUND IN intermediate filament (inferred); nucleolus (inferred); nucleoplasm (inferred)				Pig	50	symbol	gene, protein-coding, MODEL [RefSeq]
18633768	TLK2	tousled like kinase 2	ENCODES a protein that exhibits transmembrane transporter binding (ortholog); INVOLVED IN peptidyl-serine phosphorylation (ortholog); protein phosphorylation (ortholog); ASSOCIATED WITH autistic disorder (ortholog); autosomal dominant intellectual developmental disorder 57 (ortholog); Developmental ... (more) Disease (ortholog); FOUND IN intermediate filament (inferred); nucleolus (inferred); nucleoplasm (inferred)				Green Monkey	51	symbol	gene, protein-coding, MODEL [RefSeq]
155253122	tlk2.L						African Clawed Frog		symbol	gene, null
155251386	tlk2.S						African Clawed Frog		symbol	gene, null
16569912	AC090114.3	pseudogene similar to part of tousled-like kinase 2 (TLK2)					Human		name	gene, unprocessed_pseudogene
1625821	TLK2P1	tousled like kinase 2 pseudogene 1		17	34036704	34040050	Human		symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]
1625805	TLK2P2	tousled like kinase 2 pseudogene 2		10	37818406	37820987	Human		symbol , COSMIC , Human Proteome Map , old_gene_symbol	gene, pseudo, INFERRED [RefSeq]