| 3846 | Tfec | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN positive regulation of tra nscription by RNA polymerase II; regulation of DNA-templated transcription; cellular response to heat (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide | 4 | 46072093 | 46146200 | Rat | 98 | symbol , PhenoGen , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 735415 | TFEC | transcription factor EC | This gene encodes a member of the micropthalmia (MiT) family of basic helix-loop-helix leucine zipper transcription factors. MiT transcription factors regulate the expression of target genes by binding to E-box recognition sequences as homo- or heterodimers, and play roles in multiple cellular proce sses including survival, growth and differentiation. The encoded protein is a transcriptional activator of the nonmuscle myosin II heavy chain-A gene, and may also co-regulate target genes in osteoclasts as a heterodimer with micropthalmia-associated transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] | 7 | 115935152 | 116159896 | Human | 98 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 735416 | Tfec | transcription factor EC | Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular response to heat. Predicted to be located in cytosol and nucleoplasm. Predicted to be a ctive in nucleus. Is expressed in several structures, including central nervous system; gut; male reproductive gland or organ; trunk somite; and urinary system. Orthologous to human TFEC (transcription factor EC). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 16830926 | 16898463 | Mouse | 108 | symbol , PhenoGen , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 9000101 | Tfec | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cell ular response to heat (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm (ortholog) | NW_004955432 | 21751697 | 21813199 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11788728 | TFEC | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to heat (o rtholog); negative regulation of transcription by RNA polymerase II (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm (ortholog) | 7 | 107900876 | 107996752 | Bonobo | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12410073 | TFEC | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to heat (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN cytoplasm (in ferred); nucleoplasm (inferred); nucleus (inferred) | 14 | 54977603 | 55194728 | Dog | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12680545 | Tfec | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to heat (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm ( inferred); nucleus (inferred) | NW_004936589 | 2971350 | 3001480 | Squirrel | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13880361 | TFEC | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to heat (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm ( inferred); nucleus (inferred) | | | | Pig | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18628572 | TFEC | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); INVOLVED IN cellular response to heat (ortholog); regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm ( inferred); nucleus (inferred) | | | | Green Monkey | 20 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18910818 | Tfec | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to heat (o rtholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155260021 | tfec | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626050012 | Tfec | transcription factor EC | ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN cell ular response to heat (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN nucleoplasm (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405856200 | tfec.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856982 | tfec.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859196 | tfec.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405862452 | tfec.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626468478 | tfec.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405856042 | tfec.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405857441 | tfec.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405858601 | tfec.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861273 | tfec.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626188715 | tfec.S | | | | | | African Clawed Frog | | symbol | gene, null |
