TFEC (transcription factor EC) - Rat Genome Database

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Gene: TFEC (transcription factor EC) Pan paniscus
Analyze
Symbol: TFEC
Name: transcription factor EC
RGD ID: 11788728
Description: ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); sequence-specific double-stranded DNA binding (ortholog); INVOLVED IN cellular response to heat (ortholog); negative regulation of transcription by RNA polymerase II (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); pleomorphic xanthoastrocytoma (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC117981081; uncharacterized LOC117981081
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26152,760,399 - 152,937,498 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan174,770,655 - 4,947,754 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07107,900,876 - 107,996,752 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17120,598,588 - 120,823,338 (-)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
TFEC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26152,760,399 - 152,937,498 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan174,770,655 - 4,947,754 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v07107,900,876 - 107,996,752 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17120,598,588 - 120,823,338 (-)NCBIpanpan1.1PanPan1.1panPan2
TFEC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387115,935,152 - 116,159,896 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7115,935,148 - 116,159,896 (-)EnsemblGRCh38hg38GRCh38
GRCh377115,575,206 - 115,670,817 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367115,362,438 - 115,458,034 (-)NCBINCBI36Build 36hg18NCBI36
Build 347115,173,976 - 115,264,746NCBI
Celera7110,382,578 - 110,478,171 (-)NCBICelera
Cytogenetic Map7q31.2NCBI
HuRef7109,941,132 - 110,036,927 (-)NCBIHuRef
CHM1_17115,508,483 - 115,604,121 (-)NCBICHM1_1
T2T-CHM13v2.07117,250,129 - 117,474,879 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v27114,970,614 - 115,066,276 (-)NCBI
Tfec
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39616,830,926 - 16,898,463 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl616,833,372 - 16,898,440 (-)EnsemblGRCm39 Ensembl
GRCm38616,830,927 - 16,898,464 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl616,833,373 - 16,898,441 (-)EnsemblGRCm38mm10GRCm38
MGSCv37616,783,381 - 16,848,441 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36616,783,392 - 16,848,441 (-)NCBIMGSCv36mm8
Celera616,915,029 - 16,979,927 (-)NCBICelera
Cytogenetic Map6A2NCBI
cM Map67.61NCBI
Tfec
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8446,072,093 - 46,146,200 (-)NCBIGRCr8
mRatBN7.2445,106,129 - 45,180,236 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl445,107,641 - 45,180,236 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx450,100,101 - 50,172,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0446,021,794 - 46,094,161 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0444,447,122 - 44,519,608 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0444,063,533 - 44,136,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl444,065,045 - 44,136,815 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0444,670,886 - 44,744,984 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4442,422,172 - 42,495,654 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1442,541,818 - 42,615,301 (-)NCBI
Celera440,398,740 - 40,470,786 (-)NCBICelera
RH 3.4 Map4258.81RGD
Cytogenetic Map4q22NCBI
Tfec
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543221,752,044 - 21,813,292 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543221,751,697 - 21,813,199 (-)NCBIChiLan1.0ChiLan1.0
TFEC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11454,977,603 - 55,194,728 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1454,979,110 - 55,105,323 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1454,368,445 - 54,589,602 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01455,011,659 - 55,232,717 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1455,016,421 - 55,192,923 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11455,043,051 - 55,264,294 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01454,731,988 - 54,953,053 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01455,102,571 - 55,323,323 (-)NCBIUU_Cfam_GSD_1.0
Tfec
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511843,684,480 - 43,749,006 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365892,971,417 - 3,000,694 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365892,971,350 - 3,001,480 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TFEC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1830,122,494 - 30,175,484 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11829,980,394 - 30,260,226 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21832,094,390 - 32,287,701 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TFEC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12184,655,653 - 84,858,828 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2184,654,538 - 84,680,786 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604219,026,239 - 19,107,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tfec
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248273,426,277 - 3,496,989 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248273,472,157 - 3,498,689 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


RefSeq Acc Id: XM_003808658   ⟹   XP_003808706
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26152,760,399 - 152,856,229 (-)NCBI
NHGRI_mPanPan174,770,655 - 4,866,485 (-)NCBI
Mhudiblu_PPA_v07107,900,876 - 107,996,715 (-)NCBI
PanPan1.17120,598,588 - 120,694,318 (-)NCBI
Sequence:
RefSeq Acc Id: XM_055115330   ⟹   XP_054971305
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v26152,760,399 - 152,937,498 (-)NCBI
NHGRI_mPanPan174,770,655 - 4,947,754 (-)NCBI
RefSeq Acc Id: XP_003808706   ⟸   XM_003808658
- Peptide Label: isoform X2
- UniProtKB: A0A2R8Z8K1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_054971305   ⟸   XM_055115330
- Peptide Label: isoform X1
- UniProtKB: A0A2R8Z8J6 (UniProtKB/TrEMBL)
Protein Domains
bHLH   MiT/TFE transcription factors C-terminal


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000004955 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000005512.1 UniProtKB/TrEMBL
  ENSPPAT00000005547.1 UniProtKB/TrEMBL
  ENSPPAT00000005549.1 UniProtKB/TrEMBL
  ENSPPAT00000005631.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  4.10.280.10 UniProtKB/TrEMBL
InterPro bHLH_dom UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/TrEMBL
  MiT/TFE_C UniProtKB/TrEMBL
KEGG Report pps:100995454 UniProtKB/TrEMBL
NCBI Gene TFEC ENTREZGENE
PANTHER MIP04163P UniProtKB/TrEMBL
  PTHR45776:SF1 UniProtKB/TrEMBL
Pfam DUF3371 UniProtKB/TrEMBL
  HLH UniProtKB/TrEMBL
PROSITE BHLH UniProtKB/TrEMBL
SMART HLH UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/TrEMBL
UniProt A0A2R8Z8J6 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Z8K1 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R8Z8L4_PANPA UniProtKB/TrEMBL
  A0A2R8ZEX6_PANPA UniProtKB/TrEMBL
  A1YG27_PANPA UniProtKB/TrEMBL
  A1YG28_PANPA UniProtKB/TrEMBL
  A1YG29_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-04-20 TFEC  transcription factor EC  LOC117981081  uncharacterized LOC117981081  Data merged from RGD:32733109 737654 PROVISIONAL