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14 records found for search term Tdp1
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1309618Tdp1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (ortholog); double-stranded DNA binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN DNA repair (ortholog); double-strand break repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autos6124892821124960646Rat124symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1320052TDP1tyrosyl-DNA phosphodiesterase 1The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA co148995496890044764Human169symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1617429Tdp1tyrosyl-DNA phosphodiesterase 1Predicted to enable 3'-tyrosyl-DNA phosphodiesterase activity; double-stranded DNA binding activity; and single-stranded DNA binding activity. Acts upstream of or within single strand break repair. Located in nucleus. Is expressed in ovary and testis. Used to study spinocerebellar ataxia with axonal129985076799921482Mouse140symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
9039618Tdp1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (ortholog); double-stranded DNA binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN DNA repair (ortholog); double-strand break repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosNW_0049554381242179012510243Chinchilla21symbolgene, protein-coding, MODEL [RefSeq]
11766136TDP1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (inferred); double-stranded DNA binding (inferred); exonuclease activity (inferred); INVOLVED IN DNA repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ortholog); m147057406670662562Bonobo36symbolgene, protein-coding, MODEL [RefSeq]
12319545TDP1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (inferred); double-stranded DNA binding (inferred); exonuclease activity (inferred); INVOLVED IN DNA repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ortholog); m86102356461107599Dog36symbolgene, protein-coding, MODEL [RefSeq]
12645564Tdp1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (inferred); double-stranded DNA binding (inferred); exonuclease activity (inferred); INVOLVED IN DNA repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ortholog); mNW_0049364881723700217311325Squirrel36symbolgene, protein-coding, MODEL [RefSeq]
20866764TDP1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (inferred); double-stranded DNA binding (inferred); exonuclease activity (inferred); INVOLVED IN DNA damage response (inferred); DNA repair (inferred); double-strand break repair (inferred); FOUND IN cytoplasm (inferred); nuclGreen Monkey25symbolgene, protein-coding
155249707tdp1Tropical Clawed Frogsymbolgene, null
13988899TDP1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (inferred); double-stranded DNA binding (inferred); exonuclease activity (inferred); INVOLVED IN DNA repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosomal recessive cerebellar ataxia (ortholog); mPig36symbolgene, protein-coding, MODEL [RefSeq]
18446152TDP1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (ortholog); double-stranded DNA binding (ortholog); single-stranded DNA binding (ortholog); INVOLVED IN DNA repair (ortholog); double-strand break repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosGreen Monkey21symbolgene, protein-coding, MODEL [RefSeq]
14378992TDP1Yeastsymbolgene, null
18912247Tdp1tyrosyl-DNA phosphodiesterase 1ENCODES a protein that exhibits 3'-tyrosyl-DNA phosphodiesterase activity (inferred); double-stranded DNA binding (inferred); exonuclease activity (inferred); INVOLVED IN DNA repair (ortholog); double-strand break repair (ortholog); single strand break repair (ortholog); ASSOCIATED WITH autosomal reNaked Mole-Rat30symbolgene, protein-coding, MODEL [RefSeq]
155242256tdp1.LAfrican Clawed Frogsymbolgene, null