| 1305226 | Kmt5c | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone H4K20 methyltransferase activity (ortholog); INVOLVED IN DNA repair (ortholog); positive regulation of double-strand break repair via nonhomologous end joining (ortholog); positive regulation of isotype switching (ortholog); PARTICIPATES IN histone modification pathway; lysine degradation pathway; ASSOCIATED WITH Experimental Diabetes Mellitus; liver benign neoplasm; FOUND IN condensed chromosome, centromeric region (ortholog); heterochromatin (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A | 1 | 78128325 | 78135931 | Rat | 109 | old_gene_name , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1313127 | Kmt5c | lysine methyltransferase 5C | Enables histone H4K20 methyltransferase activity and histone binding activity. Involved in positive regulation of isotype switching. Located in condensed chromosome, centromeric region. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervou s system; and sensory organ. Orthologous to human KMT5C (lysine methyltransferase 5C). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 4743091 | 4750513 | Mouse | 115 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1346503 | KMT5C | lysine methyltransferase 5C | SUV420H2 and the related enzyme SUV420H1 (MIM 610881) function as histone methyltransferases that specifically trimethylate nucleosomal histone H4 (see MIM 602822) on lysine-20 (K20) (Schotta et al., 2004 [PubMed 15145825]).[supplied by OMIM, Dec 2009] | 19 | 55339876 | 55348121 | Human | 94 | old_gene_name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 8760164 | Kmt5c | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); histone H4K20 methyltransferase activity (ortholog); INVOLVED IN DNA repair (ortholog); positive regulation of double-strand break repair via nonhomologous end joining (ortholog); positive regulation of isotype switching (ortholog); PARTICIPATES IN histone modification pathway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); liver benign neoplasm (ortholog); FOUND IN condensed chromosome, centromeric region (ortholog); heterochromatin (ortholog); nucleoplasm (ortholog) | NW_004955567 | 895334 | 901240 | Chinchilla | 18 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 18901498 | Kmt5c | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (ortholog); histone binding (ortholog); S-adenosyl-L-methionine binding (ortholog); INVOLVED IN DNA repair (ortholog); positive regulation of double-strand break repair via nonhomologous end joining (ortholog); PARTICIPATES IN histone modification pa thway; ASSOCIATED WITH Experimental Diabetes Mellitus (ortholog); liver benign neoplasm (ortholog); FOUND IN heterochromatin (ortholog); nucleoplasm (ortholog); pericentric heterochromatin (ortholog) | | | | Naked Mole-Rat | 29 | old_gene_name , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 11761800 | KMT5C | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone H4K20 methyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA repair (inferred); PARTICIPATES IN histone modification pathway; ASSOCIAT ED WITH Experimental Diabetes Mellitus (ortholog); liver benign neoplasm (ortholog); FOUND IN chromosome (inferred); condensed chromosome, centromeric region (inferred); heterochromatin (inferred) | 19 | 52381963 | 52390507 | Bonobo | 33 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12288051 | KMT5C | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone H4K20 methyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA repair (inferred); PARTICIPATES IN histone modification pathway; ASSOCIAT ED WITH Experimental Diabetes Mellitus (ortholog); liver benign neoplasm (ortholog); FOUND IN chromosome (inferred); condensed chromosome, centromeric region (inferred); heterochromatin (inferred) | 1 | 102334687 | 102342090 | Dog | 31 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 12725622 | Kmt5c | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone H4K20 methyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA repair (inferred); PARTICIPATES IN histone modification pathway; ASSOCIAT ED WITH Experimental Diabetes Mellitus (ortholog); liver benign neoplasm (ortholog); FOUND IN chromosome (inferred); condensed chromosome, centromeric region (inferred); heterochromatin (inferred) | NW_004936886 | 596949 | 602959 | Squirrel | 32 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18654174 | KMT5C | lysine methyltransferase 5C | ENCODES a protein that exhibits chromatin binding (inferred); histone binding (inferred); histone H4K20 methyltransferase activity (inferred); INVOLVED IN chromatin organization (inferred); chromatin remodeling (inferred); DNA repair (inferred); PARTICIPATES IN histone modification pathway; ASSOCIAT ED WITH Experimental Diabetes Mellitus (ortholog); liver benign neoplasm (ortholog); FOUND IN chromosome (inferred); condensed chromosome, centromeric region (inferred); heterochromatin (inferred) | | | | Green Monkey | 33 | old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 2324146 | Kmt5c-ps1 | lysine methyltransferase 5C, pseudogene 1 | | 20 | 173534 | 177948 | Rat | | old_gene_name | gene, pseudo, MODEL [RefSeq] |