| 621582 | Sub1 | SUB1 regulator of transcription | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA metabolic process (ortholog); regulation of transcription by RNA poly merase II (ortholog); RNA polymerase II promoter clearance (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); transcription regulator complex (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride | 2 | 62735379 | 62747545 | Rat | 123 | symbol , old_gene_name , PhenoGen , name , ensembl_full_name | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1605698 | SUB1 | SUB1 regulator of transcription | Enables several functions, including DNA binding activity; identical protein binding activity; and transcription coactivator activity. Involved in RNA polymerase II promoter clearance; protein homooligomerization; and regulation of nucleobase-containing compound metabolic process. Located in nucleol us and nucleoplasm. Part of transcription regulator complex. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 32585557 | 32604079 | Human | 131 | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1620097 | Sub1 | SUB1 homolog, transcriptional regulator | Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase II promoter clearance; negative regulation of DNA metabolic process; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleolus and nucle oplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SUB1 (SUB1 regulator of transcription). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 11981422 | 11996091 | Mouse | 138 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8836441 | Sub1 | SUB1 regulator of transcription | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA metabolic process (ortholog); regulation of transcription by RNA poly merase II (ortholog); RNA polymerase II promoter clearance (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); transcription regulator complex (ortholog) | NW_004955426 | 18380680 | 18394627 | Chinchilla | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 11914822 | SUB1 | SUB1 regulator of transcription | ENCODES a protein that exhibits DNA binding (inferred); double-stranded DNA binding (inferred); identical protein binding (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA metabolic process (inferred); positive regulation of transcription initiation by RNA po lymerase II (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | 5 | 77728309 | 77800534 | Bonobo | 26 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12077720 | SUB1 | SUB1 regulator of transcription | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA metabolic process (ortholog); regulation of transcription by RNA poly merase II (ortholog); RNA polymerase II promoter clearance (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog) | 4 | 74931105 | 74951707 | Dog | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12655327 | Sub1 | SUB1 regulator of transcription | ENCODES a protein that exhibits DNA binding (inferred); double-stranded DNA binding (inferred); identical protein binding (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA metabolic process (inferred); positive regulation of transcription initiation by RNA po lymerase II (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936518 | 8236026 | 8249007 | Squirrel | 26 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14206697 | SUB1 | SUB1 regulator of transcription | ENCODES a protein that exhibits DNA binding (inferred); double-stranded DNA binding (inferred); identical protein binding (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA metabolic process (inferred); positive regulation of transcription initiation by RNA po lymerase II (inferred); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 29 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 14379640 | SUB1 | | | | | | Yeast | | symbol | gene, null |
| 18513820 | SUB1 | SUB1 regulator of transcription | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA metabolic process (ortholog); regulation of transcription by RNA poly merase II (ortholog); RNA polymerase II promoter clearance (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); transcription regulator complex (ortholog) | | | | Green Monkey | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18906139 | Sub1 | SUB1 regulator of transcription | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA metabolic process (ortholog); regulation of transcription by RNA poly merase II (ortholog); RNA polymerase II promoter clearance (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); transcription regulator complex (ortholog) | | | | Naked Mole-Rat | 27 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155254245 | sub1 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626003867 | Sub1 | SUB1 regulator of transcription | ENCODES a protein that exhibits double-stranded DNA binding (ortholog); identical protein binding (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA metabolic process (ortholog); regulation of transcription by RNA poly merase II (ortholog); RNA polymerase II promoter clearance (ortholog); PARTICIPATES IN RNA polymerase III transcription pathway; FOUND IN nucleolus (ortholog); nucleoplasm (ortholog); transcription regulator complex (ortholog) | | | | Black Rat | 20 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155247204 | sub1.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155249108 | sub1.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7736402 | Sub1-ps1 | SUB1 regulator of transcription, pseudogene 1 | | 1 | 88761700 | 88762124 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 7711557 | Sub1-ps2 | SUB1 regulator of transcription, pseudogene 2 | | 16 | 76443779 | 76444232 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 41183496 | Sub1-ps3 | SUB1 regulator of transcription, pseudogene 3 | | 1 | 16084174 | 16084922 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 9337598 | Sub1-ps4 | SUB1 regulator of transcription, pseudogene 4 | | 2 | 196060516 | 196067603 | Rat | | symbol , PhenoGen , name | gene, pseudo, MODEL [RefSeq] |
| 30307884 | ARHGEF1 | Rho guanine nucleotide exchange factor 1 | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants h ave been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008] | 19 | 41883184 | 41930141 | Human | 124 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 2291764 | SUB1P1 | SUB1 pseudogene 1 | | 8 | 11789952 | 11791285 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6484035 | SUB1P2 | SUB1 pseudogene 2 | | 14 | 74305423 | 74306063 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 10399399 | SUB1P3 | SUB1 pseudogene 3 | | 16 | 4562616 | 4563249 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 6484037 | SUB1P4 | SUB1 pseudogene 4 | | 16 | 23537004 | 23538175 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 12064499 | LOC100686657 | SUB1 homolog (S. cerevisiae) pseudogene | | 4 | 37071553 | 37072312 | Dog | | name | gene, pseudo, MODEL [RefSeq] |