Sub1 (SUB1 homolog, transcriptional regulator)

Gene: Sub1 (SUB1 homolog, transcriptional regulator) Mus musculus

Analyze

Symbol:

Sub1

Name:

SUB1 homolog, transcriptional regulator

RGD ID:

1620097

MGI Page

MGI

Description:

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in RNA polymerase II promoter clearance; negative regulation of DNA duplex unwinding; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SUB1 (SUB1 regulator of transcription).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

activated RNA polymerase II transcriptional coactivator p15; AI842364; P1; p14; P15; P9; Pc; Pc4; positive cofactor 4; RNA polymerase II transcriptional coactivator; Rpo2; Rpo2tc1; single-stranded DNA-binding protein p9; SUB1 homolog (S. cerevisiae)

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SUB1 (SUB1 regulator of transcription)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Sub1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Sub1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SUB1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SUB1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Sub1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SUB1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SUB1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Sub1 (SUB1 regulator of transcription)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Sub1 (SUB1 regulator of transcription)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SUB1 (SUB1 regulator of transcription)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	sub1b (SUB1 homolog, transcriptional regulator b)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoInspector\|PANTHER\|PhylomeDB\|ZFIN)
Danio rerio (zebrafish):	sub1a (SUB1 homolog, transcriptional regulator a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	T13F2.2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	SUB1	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Ssb-c31a	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	sub1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)

Related Pseudogenes:

Gm2986

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	11,981,422 - 11,996,091 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	11,981,425 - 11,997,069 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	11,981,336 - 11,996,038 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	11,981,339 - 11,996,983 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	11,911,094 - 11,925,762 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	11,926,064 - 11,940,732 (-)	NCBI		MGSCv36	mm8
Celera	15	11,766,100 - 11,780,766 (-)	NCBI		Celera
Cytogenetic Map	15	A1	NCBI
cM Map	15	5.9	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(S)-nicotine (EXP)

1,2-dichloroethane (EXP)

1,2-dimethylhydrazine (EXP)

17alpha-ethynylestradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-methylcholine (ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin M1 (ISO)

ammonium chloride (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

clobetasol (EXP)

copper atom (ISO)

copper(0) (ISO)

coumarin (ISO)

crocidolite asbestos (EXP)

cyclosporin A (ISO)

dexamethasone (ISO)

dextran sulfate (EXP)

diarsenic trioxide (ISO)

dicrotophos (ISO)

diuron (ISO)

doxorubicin (ISO)

endosulfan (ISO)

epoxiconazole (EXP)

ethanol (EXP,ISO)

ethyl methanesulfonate (ISO)

fenthion (EXP)

fipronil (ISO)

formaldehyde (ISO)

FR900359 (ISO)

gentamycin (ISO)

geraniol (ISO)

indometacin (ISO)

ivermectin (ISO)

lamivudine (EXP)

mercury atom (ISO)

mercury(0) (ISO)

methidathion (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

methylparaben (ISO)

mitomycin C (ISO)

nicotine (EXP)

paclitaxel (ISO)

PhIP (ISO)

quercetin (ISO)

rotenone (ISO)

sodium arsenite (ISO)

Tributyltin oxide (EXP)

triptonide (EXP)

valproic acid (ISO)

vorinostat (ISO)

zidovudine (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

DNA duplex unwinding (ISO)

negative regulation of DNA duplex unwinding (ISO)

negative regulation of DNA metabolic process (ISO)

positive regulation of transcription initiation by RNA polymerase II (IEA)

protein homooligomerization (ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (ISO)

RNA polymerase II promoter clearance (ISO)

Cellular Component

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (IBA)

transcription regulator complex (IBA,ISO)

Molecular Function

DNA binding (IEA)

DNA helicase activity (ISO)

DNA-binding transcription factor binding (ISO)

double-stranded DNA binding (ISO)

identical protein binding (ISO)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IDA)

single-stranded DNA binding (ISO)

transcription coactivator activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA polymerase III transcription pathway (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

prenatal lethality (IAGP)

transmission ratio distortion (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Transcription reinitiation by RNA polymerase III.	Dieci G, etal., Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):331-41. doi: 10.1016/j.bbagrm.2012.10.009. Epub 2012 Nov 3.
2.	Regulation of pol III transcription by nutrient and stress signaling pathways.	Moir RD and Willis IM, Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):361-75. doi: 10.1016/j.bbagrm.2012.11.001. Epub 2012 Nov 16.
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:3372536	PMID:7798170	PMID:8889548	PMID:10349636	PMID:10922068	PMID:11042159	PMID:11076861	PMID:11125038	PMID:11217851	PMID:12466851	PMID:12477932	PMID:12520002
PMID:12904583	PMID:14610273	PMID:14681479	PMID:15489334	PMID:16003322	PMID:16033648	PMID:16141072	PMID:16141073	PMID:16602821	PMID:16982701	PMID:18287559	PMID:18973680
PMID:19047459	PMID:20059953	PMID:21267068	PMID:21677750	PMID:21873635	PMID:22354994	PMID:22794259	PMID:23390484	PMID:23665500	PMID:25737280	PMID:26740582	PMID:27471272
PMID:30457570	PMID:30550785	PMID:32325033	PMID:32554809	PMID:33357426	PMID:35012549

Genomics

Comparative Map Data

Sub1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	11,981,422 - 11,996,091 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	11,981,425 - 11,997,069 (-)	Ensembl		GRCm39 Ensembl
GRCm38	15	11,981,336 - 11,996,038 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	11,981,339 - 11,996,983 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	11,911,094 - 11,925,762 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	11,926,064 - 11,940,732 (-)	NCBI		MGSCv36	mm8
Celera	15	11,766,100 - 11,780,766 (-)	NCBI		Celera
Cytogenetic Map	15	A1	NCBI
cM Map	15	5.9	NCBI

SUB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	32,585,557 - 32,604,079 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	32,531,633 - 32,604,079 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	32,585,663 - 32,604,185 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	32,621,434 - 32,637,820 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	5	32,467,253 - 32,485,840 (+)	NCBI		Celera
Cytogenetic Map	5	p13.3	NCBI
HuRef	5	32,553,427 - 32,572,031 (+)	NCBI		HuRef
CHM1_1	5	32,587,724 - 32,606,294 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	5	32,699,227 - 32,717,759 (+)	NCBI		T2T-CHM13v2.0

Sub1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	62,735,379 - 62,747,545 (-)	NCBI		GRCr8
mRatBN7.2	2	61,005,646 - 61,020,486 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	61,005,666 - 61,020,436 (-)	Ensembl		mRatBN7.2 Ensembl
mRatBN7.2 Ensembl	2	43,299,239 - 43,299,924 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	68,138,134 - 68,150,187 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	66,259,692 - 66,271,744 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	61,261,040 - 61,273,093 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	62,019,902 - 62,034,704 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	62,022,567 - 62,034,628 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	82,656,079 - 82,670,881 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	61,418,076 - 61,430,139 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	61,346,310 - 61,356,225 (-)	NCBI
Celera	2	57,672,589 - 57,684,652 (+)	NCBI		Celera
Cytogenetic Map	2	q16	NCBI

Sub1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955426	18,380,117 - 18,394,627 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955426	18,380,680 - 18,394,627 (+)	NCBI	ChiLan1.0	ChiLan1.0

SUB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	4	77,698,383 - 77,770,692 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	5	75,852,014 - 75,924,250 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	77,728,309 - 77,800,534 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	83,112,131 - 83,130,755 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	5	83,112,131 - 83,130,755 (-)	Ensembl	panpan1.1		panPan2

SUB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	74,931,105 - 74,951,707 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	74,933,620 - 74,951,573 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	74,569,825 - 74,588,278 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	75,452,940 - 75,471,575 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	4	75,190,470 - 75,208,907 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	75,319,042 - 75,337,517 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	75,849,695 - 75,868,156 (-)	NCBI		UU_Cfam_GSD_1.0

Sub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	223,122,805 - 223,137,782 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936518	8,233,338 - 8,249,549 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936518	8,236,026 - 8,249,007 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SUB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	16	18,758,962 - 18,779,419 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	16	18,758,886 - 18,779,421 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SUB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	4	31,860,744 - 31,879,851 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	4	31,860,830 - 31,877,070 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666071	22,118,817 - 22,135,778 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Sub1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624759	22,009,266 - 22,037,394 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624759	22,010,097 - 22,027,807 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Sub1
320 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	1152
Count of miRNA genes:	590
Interacting mature miRNAs:	738
Transcripts:	ENSMUST00000022816, ENSMUST00000110504, ENSMUST00000129533, ENSMUST00000134414
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357459	Nhdlq7_m	non-HDL QTL 7 (mouse)			Not determined		15	1	20489829	Mouse
1302121	Cliff_m	cliff drop aversion (mouse)			Not determined		15	1	20489829	Mouse
1300953	Bdt5_m	bone density traits 5 (mouse)			Not determined		15	1	20489829	Mouse
5491193	Mobq4_m	multigenic obesity QTL 4 (mouse)			Not determined		15	1	20489829	Mouse
1301662	Faq8_m	fluctuating asymmetry QTL 8 (mouse)			Not determined		15	1	20489829	Mouse
1301023	Sluc24_m	susceptibility to lung cancer 24 (mouse)			Not determined		15	1	20489829	Mouse
4141541	Tglq3_m	triglyceride QTL 3 (mouse)			Not determined		15	1	20489829	Mouse
11062069	Bpq31_m	blood pressure QTL 31 (mouse)					15	1	26273195	Mouse
4141446	Ffaq4_m	free fatty acid QTL 4 (mouse)			Not determined			1	27101390	Mouse
1300594	Eae2_m	susceptibility to experimental allergic encephalomyelitis 2 (mouse)			Not determined		15	1	31218736	Mouse
1301136	Pgia8_m	proteoglycan induced arthritis 8 (mouse)			Not determined		15	3240167	24388176	Mouse
4141358	Ath22_m	atherosclerosis 22 (mouse)			Not determined			3464652	37464652	Mouse
10401902	Sicd2_m	seizure-induced cell death 2 (mouse)			Not determined		15	3474389	71197538	Mouse
4141952	W3q7_m	weight 3 weeks QTL 7 (mouse)			Not determined			3489694	78601286	Mouse
4142252	Tailaq4_m	tail length adjusted QTL 4 (mouse)			Not determined			3489694	78601286	Mouse
4142448	Tailq6_m	tail length QTL 6 (mouse)			Not determined			3489694	78601286	Mouse
1357559	Scfq2_m	subcutaneous fat pad weight QTL 2 (mouse)			Not determined		15	3489694	78601286	Mouse
1357659	Epfpq4_m	epididymal fat percentage QTL 4 (mouse)			Not determined		15	3489694	78601286	Mouse
11252136	Modvl4_m	modifier of vacuolated lens (mouse)					15	5620494	39620614	Mouse
26884409	Bzwq16_m	bi-zygomatic width QTL 16, 16 week (mouse)					15	6129481	38000244	Mouse
26884384	Skwq12_m	skull length QTL 12, 16 week (mouse)					15	6129481	50763396	Mouse
26884387	Skwq8_m	skull length QTL 8, 10 week (mouse)					15	6129481	68271849	Mouse
26884412	Bzwq10_m	bi-zygomatic width QTL 10, 10 week (mouse)					15	6129481	71471849	Mouse
26884417	Bzwq4_m	bi-zygomatic width QTL 4, 5 week (mouse)					15	6129481	72471849	Mouse
27226786	Feml11_m	femur length 11, 5 week (mouse)					15	6129481	75871849	Mouse
27095932	Ulnl11_m	ulna length 11, 16 week (mouse)					15	6129481	76384200	Mouse
27226717	Tibw4_m	tibia width 4, proximal, 10 week (mouse)					15	6129481	78684200	Mouse
27226734	Tibmd5_m	tibia midshaft diameter 5, 10 week (mouse)					15	6129481	86684201	Mouse
26884442	Sklq6_m	skull length QTL 6, 5 week (mouse)					15	6129481	100797881	Mouse
26884429	Zlq6_m	zygomatic length QTL 6, 10 week (mouse)					15	6829481	44963396	Mouse
27226721	Tibw8_m	tibia width 8, proximal, 16 week (mouse)					15	6929481	75871849	Mouse
27226773	Tibl16_m	tibia length 16, 10 week (mouse)					15	6929481	75871849	Mouse
27226777	Tibl8_m	tibia length 8, 5 week (mouse)					15	6929481	84584201	Mouse
27095940	Ulnl8_m	ulna length 8, 10 week (mouse)					15	7229481	55263396	Mouse
27226759	Feml17_m	femur length 17, 10 week (mouse)					15	7629481	55263396	Mouse
27226755	Feml22_m	femur length 22, 16 week (mouse)					15	7629481	59271849	Mouse
27095922	Pglq11_m	pelvic girdle length QTL 11, 10 week (mouse)					15	8129484	38763395	Mouse
26884439	Sklq11_m	skull length QTL 11, 10 week (mouse)					15	8129484	47663396	Mouse
10412172	Habiir5_m	hyperoxic acute lung injury imprinted region 5 (mouse)			Not determined		15	9273022	43311880	Mouse
4140994	Shali3_m	survival time to hyperoxic acute lung injury 3 (mouse)			Not determined			9273022	43311880	Mouse
4141192	Ssrq2_m	stress response QTL 2 (mouse)			Not determined			9273022	56186850	Mouse
1301433	Rapop5_m	radiation-induced apoptosis 5 (mouse)			Not determined		15	9273022	79474762	Mouse

Markers in Region

RH128729

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	13	72,472,099 - 72,472,304	UniSTS	GRCm38
MGSCv37	13	72,609,547 - 72,609,752	UniSTS	GRCm37
Celera	13	74,798,436 - 74,798,641	UniSTS
Celera	11	99,677,110 - 99,677,315	UniSTS
Cytogenetic Map	15	A2	UniSTS
Cytogenetic Map	13	C1	UniSTS

Sub1

Mouse Assembly	Chr	Position (strand)	Source
Celera	11	99,677,038 - 99,677,632	UniSTS
Cytogenetic Map	15	A2	UniSTS
cM Map	15		UniSTS

RH143136

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	15	11,982,976 - 11,983,194	UniSTS	GRCm38
MGSCv37	15	11,912,731 - 11,912,949	UniSTS	GRCm37
Celera	15	11,767,737 - 11,767,955	UniSTS
Cytogenetic Map	15	A2	UniSTS

AI842364

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	15	11,981,394 - 11,981,476	UniSTS	GRCm38
MGSCv37	15	11,911,149 - 11,911,231	UniSTS	GRCm37
Celera	15	11,766,155 - 11,766,237	UniSTS
Cytogenetic Map	15	A2	UniSTS
Whitehead/MRC_RH	15	127.17	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001411715	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_011294	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC121860	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK030954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK048371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK049260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK132021	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK146335	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK151734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK154114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC010967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	J03750	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000022816 ⟹ ENSMUSP00000022816

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	15	11,981,425 - 11,996,144 (-)	Ensembl
GRCm38.p6 Ensembl	15	11,981,339 - 11,996,058 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000110504 ⟹ ENSMUSP00000106130

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	15	11,984,127 - 11,997,069 (-)	Ensembl
GRCm38.p6 Ensembl	15	11,984,041 - 11,996,983 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000129533

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	15	11,986,220 - 11,996,098 (-)	Ensembl
GRCm38.p6 Ensembl	15	11,986,134 - 11,996,012 (-)	Ensembl

RefSeq Acc Id:

ENSMUST00000134414

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	15	11,986,540 - 11,995,836 (-)	Ensembl
GRCm38.p6 Ensembl	15	11,986,454 - 11,995,750 (-)	Ensembl

RefSeq Acc Id:

NM_001411715 ⟹ NP_001398644

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	15	11,981,422 - 11,996,091 (-)	NCBI

RefSeq Acc Id:

NM_011294 ⟹ NP_035424

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	15	11,981,422 - 11,996,091 (-)	NCBI
GRCm38	15	11,981,339 - 11,996,007 (-)	NCBI
MGSCv37	15	11,911,094 - 11,925,762 (-)	RGD
Celera	15	11,766,100 - 11,780,766 (-)	RGD
cM Map	15		ENTREZGENE

Sequence:

show sequence

TCAGTCCGGAGTAGGCGAGCGAGCGAGGCAGAGGTTTTTGGTCGGCCGGAGCGGAGCAATGCCT
AAATCAAAGGAACTTGTTTCTTCAAGCTCTTCAGGCAGTGATTCGGACAGCGAAGTTGAAAAAA
AGTTAAAGAGGAAAAAGCAAGCGGTTCCAGAGAAGCCCGTGAAGAAGCAGAAGCCTGGTGAGAC
TTCTAGAGCACTGGCATCCTCCAAGCAGAGCAGCAGCAGCAGAGATGACAACATGTTCCAGATT
GGAAAGATGAGATATGTCAGTGTTCGGGACTTCAAAGGAAAAATTCTAATTGATATTAGAGAAT
ATTGGATGGATTCAGAAGGTGAAATGAAACCAGGAAGAAAAGGTATTTCTTTAAACATGGAACA
ATGGAGCCAGCTGAAGGAACAGATCTCTGATATAGATGACGCAGTAAGAAAGCTGTAAAATCTG
AGCCATATCAAACCTGTACTGTTGTAGTTGTCTTTTTACATTGGCTTTTGTTTTCTAAATGTTG
TTTTCCAAGCTGTTGTATATTTGGATTGCAGAACAATTTGTAAGACAAATACTTTTTTTTAATG
TGCATTATTAAAATGTTCTAAGTGAAGCTAATTGTCAAGTTTATTAAAGAGGATTGCTTTGTGC
CCCCTACCTAGTGTGTAAAATAAAGTCAGATCATTACAATCTTAACTGTGGTACCCTTTTTTGA
TCAAAAAAACCTAGTTACTGTTTAAGGCCAAAAGAACAACTAGGCACACTGTTGAGTCAGCTTA
CATTCAGAAGGATTTGTATTACATTGAGTTTCTTAGATTGCTTTGTGAAATGTATACTCAGCCT
TTTTCTTTCCAACCAGATTTACTGCGTTTTCCTCTCCAGGACTTCTCCCTACCACAATAACTTA
TCTTTTCTTCAGTTCTCTTAGTGCTCAAGTTTAAATCACTCTTTACTCAGATAGATTACGCTTA
TTTAGAAAGTCAAACTGTCAGTTTTGTTGCCTCCTAAGTCTACTGTGCTAATTACTAGTATCTG
TTTGGCAACATGACTTATATGAGAACTCCAAGCAAGTGTATGTCATTATTCATAGTGCTCTGTG
TAGATGTTGCTTAGTTTACAGAACATAGTGACTTTGATGTCTGATGAGCTGTCACTCAGTAAAC
ATTTGTGCTAGGGTGATGGTTATAAAGTCAGATATTAAACTAGATTAGACTTGTAAAAAGTGTG
AAACTTACTGGCCTACTGTTATATTCTAATAATGTGTGGATTCTATGTAGTCAGATGTGGCACT
GAGCTCAACTGTGGTAGGTTCTGTGGGCAGTTTTAGAGTTGACTGTTCTACAGTTAATCTGGAC
AAGTGACTTCCAGACTTGATGTTAACTAGGTTTGATAGACATTTCCATTGGTTTTCATTTCAAT
TGTGATGATTAAGCAAGCAGACAGGCACATGTTTTAGGGACATTGCTCCAATGAAAAGGGCATA
GTGTTCTGAGGGAAAATGTTTGCAAAGGAAAGTCACCACACTGAAGGGAGCTAGCCTGTGATGA
GAAAGGAACTTTCTTGAAACTAAATGTTGTGCACATGATATGTTGGTGATAACATTAAGATGGG
TCTTCGTAGAATAATAGCTAACAAGGACAATTTATAGATGTGAAAAAATGCTGCCACTAAGGGC
TGCCATATCAGAATTGCACTGTCATACTGAGTCCCACCGTCTAAGCATTTTATAGAACTGTTAA
GGATTAAATTTAAAAAACAGTCTGCCAGGCCTCATGTGGTTAACTGTCCTCCCCACAGATACTC
TTTAGGTAACTTTTTAGTGTGTTACTCCAAATTGATACATATATATCAAAGGGTTTAAGATATA
TACCATAGCTCATTCTTGAGGGATGATCCTCTTATAATGTGTTGCATTTCATTGATTTTATAAA
GTATTCCTTATTTGTCATGTAAAGAAAGGATAGTTAGAACATAAGACTGGTTTGGTGCAGATGA
GGGGAGAATAACAGGTAAATTCCTGAGGCCATGTGTTATATGTACATTTCAGCTGTCCGATTGC
AGAGATCTGCCGTCTGCTACCTAGGCATTGCTAGCTGCTTAGCATAAAATTCCATGTGGAAAGC
TTTCTCGGGCATAATTTGTTAGGTTGATAGCTAAATACATTCACTAATGTTATACCAGAGTTGT
TGTTATTTTTCTTTGTGTGTTGAAAAGGAAAATTGAGTTAAAAGAAGAGGAAGGACTTTTCAGA
TGGAAAAGAAAGGGTACAGTCCTTCTATTTTGCGTTCAGATGCCTTTCTCCTCAGTGTCTTAGT
TTCTTTTCTGTTGCTGTGGTGAAGTGCCCTGACAGAAGCAGCCAAGGGAGAAAGGGTTTATCCT
GACTCACAGTTCCATGTTCCAGTCCGTTGTCGCATTGTCACAGTGGCAGGAACTCCAGACATCT
GGCCACATGGCTCCATAGCCAGGAAGCTGAGAGCTGTGATTGCATGCTCAGTTCCTTTTTGTCT
CATTAACCTGAGCCCAGGAGCTGGAGTTGGCCACAGCAGGCAAGATGATTCTCCAGACATCATG
CCTAGAGGCCTATCTTTTGGGTAGTTCTAGATTCTGTTGAACTAATAACCATCATAGTAAGTTT
TCTCCCAGGAAGAAGGCTTGACATTTTAAGGCATAATATCTTATTTTGTAACACTAAAATAATT
AGATCTGCTGCCAGGTTTTGCCCTTTAATATGCTCCATAGTAAGGCTTCCAAATGGGTTTTCCT
CTTAGGGTAAAAAGCCTTTGGCCAATTTCCACAATCACTGAAAAAGAAAAACTCAGATTTTCTT
TTGTTTGCTTCACAAATGCCTAAAATCTTGAGAAATACTACCTCCTTACCTAGTCAAGACGCTG
TGATAACCAGTCTGTGCTGCGTAGTGTTGGAGTCAGCAGCGTGGGGAAAACCGTGGGGAAAGAG
CATCCTGGTCTGGCTGCAAAGGGAGGAAGGGATTGAACAGTTATGTAAGCGTTCCTGACAGGAA
CGCTAGCACAGAGCTTGCCATAGAGCCTGTGAACGTCTTCAGAACCGTTGAGTTATATTTAGGT
ATCTTTTCTGAATTTCTTTGTGGTTCACTTTTTATAGAAATTAATGTAGTGAAACACTAAAGAT
TTTTTTCTTAAGAAAGGTATTTTTTTCCAGATAAACTATAATGTAAACATGCATCTAGTGAGAA
GTATGTGACTCTGTAATTGTGGAATGACTGTATGCTTTGTTTAGTACATCTTCCGTGGAGGTGT
CAATGAACCTATTATTCCACCTGTGAATATTTTAAATGTTGAATAAAAACAAGAAAC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001398644	(Get FASTA)	NCBI Sequence Viewer
	NP_035424	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA37317	(Get FASTA)	NCBI Sequence Viewer
	AAH10967	(Get FASTA)	NCBI Sequence Viewer
	BAC33314	(Get FASTA)	NCBI Sequence Viewer
	BAC33642	(Get FASTA)	NCBI Sequence Viewer
	BAE20946	(Get FASTA)	NCBI Sequence Viewer
	BAE27090	(Get FASTA)	NCBI Sequence Viewer
	BAE30649	(Get FASTA)	NCBI Sequence Viewer
	BAE32384	(Get FASTA)	NCBI Sequence Viewer
	EDL03273	(Get FASTA)	NCBI Sequence Viewer
	EDL03274	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000022816
	ENSMUSP00000022816.9
	ENSMUSP00000106130.2
GenBank Protein	P11031	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_035424 ⟸ NM_011294
- UniProtKB:	Q3UJR5 (UniProtKB/Swiss-Prot), Q543N2 (UniProtKB/Swiss-Prot), P11031 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MPKSKELVSSSSSGSDSDSEVEKKLKRKKQAVPEKPVKKQKPGETSRALASSKQSSSSRDDNMF QIGKMRYVSVRDFKGKILIDIREYWMDSEGEMKPGRKGISLNMEQWSQLKEQISDIDDAVRKL hide sequence

RefSeq Acc Id:

ENSMUSP00000106130 ⟸ ENSMUST00000110504

RefSeq Acc Id:

ENSMUSP00000022816 ⟸ ENSMUST00000022816

RefSeq Acc Id:	NP_001398644 ⟸ NM_001411715
- UniProtKB:	Q3UJR5 (UniProtKB/Swiss-Prot), P11031 (UniProtKB/Swiss-Prot), Q543N2 (UniProtKB/Swiss-Prot)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P11031-F1-model_v2	AlphaFold	P11031	1-127	view protein structure

Promoters

RGD ID:

6826518

Promoter ID:

MM_KWN:18058

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day1, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, 3T3L1_Day6, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

OTTMUST00000057571, OTTMUST00000057573, OTTMUST00000057574

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	15	11,925,471 - 11,925,971 (-)	MPROMDB

RGD ID:

8683438

Promoter ID:

EPDNEW_M19750

Type:

initiation region

Name:

Sub1_1

Description:

Mus musculus SUB1 homolog , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	15	11,996,005 - 11,996,065	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:104811	AgrOrtholog
Ensembl Genes	ENSMUSG00000022205	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000022816	ENTREZGENE
	ENSMUST00000022816.15	UniProtKB/Swiss-Prot
	ENSMUST00000110504.2	UniProtKB/Swiss-Prot
InterPro	PC4	UniProtKB/Swiss-Prot
	ssDNA-bd_transcriptional_reg	UniProtKB/Swiss-Prot
	Sub1/Tcp4-like	UniProtKB/Swiss-Prot
KEGG Report	mmu:20024	UniProtKB/Swiss-Prot
MGD	MGI:104811	ENTREZGENE
NCBI Gene	20024	ENTREZGENE
PANTHER	ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15	UniProtKB/Swiss-Prot
	PTHR13215	UniProtKB/Swiss-Prot
Pfam	PC4	UniProtKB/Swiss-Prot
PhenoGen	Sub1	PhenoGen
Superfamily-SCOP	SSF54447	UniProtKB/Swiss-Prot
UniProt	P11031	ENTREZGENE
	Q3UJR5	ENTREZGENE
	Q543N2	ENTREZGENE
	TCP4_MOUSE	UniProtKB/Swiss-Prot
UniProt Secondary	Q3UJR5	UniProtKB/Swiss-Prot
	Q543N2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-04-02	Sub1	SUB1 homolog, transcriptional regulator		SUB1 homolog (S. cerevisiae)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

RGD Manual Annotations

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

RGD Manual Annotations

Mammalian Phenotype