| 1311114 | Strap | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (ortholog); signaling receptor binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cell differentiation (ortholog); maintenance of gastrointestinal epithelium (ortholog); PARTICIPATES IN tran sforming growth factor-beta Smad dependent signaling pathway; RNA transport pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil | 4 | 172377325 | 172391573 | Rat | 138 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1322398 | STRAP | serine/threonine kinase receptor associated protein | Enables RNA binding activity. Involved in maintenance of gastrointestinal epithelium and spliceosomal snRNP assembly. Acts upstream of with a positive effect on negative regulation of transforming growth factor beta receptor signaling pathway. Located in cytosol. Part of SMN complex. Implicated in a denocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 12 | 15882387 | 15903478 | Human | 123 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1322399 | Strap | serine/threonine kinase receptor associated protein | Enables U2 snRNP binding activity; mRNA binding activity; and signaling receptor binding activity. Involved in alternative mRNA splicing, via spliceosome; neuron differentiation; and protein-RNA complex assembly. Acts upstream of or within negative regulation of transcription by RNA polymerase II; n egative regulation of transforming growth factor beta receptor signaling pathway; and retinoic acid catabolic process. Is active in nucleus. Is expressed in several structures, including alimentary system; branchial arch; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in adenocarcinoma; colorectal carcinoma; large cell carcinoma; lung carcinoma; and squamous cell neoplasm. Orthologous to human STRAP (serine/threonine kinase receptor associated protein). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 137712080 | 137728928 | Mouse | 139 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8827163 | Strap | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (ortholog); signaling receptor binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cell differentiation (ortholog); maintenance of gastrointestinal epithelium (ortholog); PARTICIPATES IN tran sforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | NW_004955413 | 12533422 | 12558138 | Chinchilla | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11736892 | STRAP | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (ortholog); signaling receptor binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cell differentiation (ortholog); maintenance of gastrointestinal epithelium (ortholog); PARTICIPATES IN tran sforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | 12 | 15883512 | 15904778 | Bonobo | 31 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12207322 | STRAP | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (inferred); signaling receptor binding (inferred); U2 snRNP binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | 27 | 30800853 | 30817578 | Dog | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12593825 | Strap | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (inferred); RNA binding (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); PART ICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | NW_004936587 | 1679570 | 1700610 | Squirrel | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14027709 | STRAP | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits kinase activity (inferred); mRNA binding (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18689529 | STRAP | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (inferred); RNA binding (inferred); signaling receptor binding (inferred); INVOLVED IN negative regulation of transcription by RNA polymerase II (ortholog); negative regulation of transforming growth factor beta receptor signaling pathway (ortholog); PART ICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18920917 | Strap | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (ortholog); signaling receptor binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cell differentiation (ortholog); maintenance of gastrointestinal epithelium (ortholog); PARTICIPATES IN tran sforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | | | | Naked Mole-Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241930 | strap | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625899087 | Strap | serine/threonine kinase receptor associated protein | ENCODES a protein that exhibits mRNA binding (ortholog); signaling receptor binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN alternative mRNA splicing, via spliceosome (ortholog); cell differentiation (ortholog); maintenance of gastrointestinal epithelium (ortholog); PARTICIPATES IN tran sforming growth factor-beta Smad dependent signaling pathway; ASSOCIATED WITH adenocarcinoma (ortholog); colorectal carcinoma (ortholog); Colorectal Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleus (ortholog) | | | | Black Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155253563 | strap.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155241929 | strap.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1603357 | SRFBP1 | serum response factor binding protein 1 | Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to be located in perinuclear region of cytoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 5 | 121961975 | 122078935 | Human | 67 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1311284 | Ttc5 | tetratricopeptide repeat domain 5 | ENCODES a protein that exhibits chromatin binding (ortholog); DNA binding (ortholog); ribosome binding (ortholog); INVOLVED IN cellular response to starvation (ortholog); DNA damage response (ortholog); positive regulation of mRNA catabolic process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH NEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic vesicle (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin | 15 | 26466613 | 26484269 | Rat | 85 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1322658 | TTC5 | tetratricopeptide repeat domain 5 | Enables ribosome binding activity. Involved in positive regulation of mRNA catabolic process. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025] | 14 | 20286227 | 20305951 | Human | 115 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1359398 | Srfbp1 | serum response factor binding protein 1 | INVOLVED IN DNA-templated transcription (inferred); ASSOCIATED WITH thoracic aortic aneurysm (ortholog); FOUND IN nucleus (ortholog); INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 18 | 48118740 | 48139824 | Rat | 62 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1616791 | Srfbp1 | serum response factor binding protein 1 | Predicted to be involved in maturation of SSU-rRNA. Located in nucleus. Is expressed in several structures, including axial musculature; genitourinary system; neural ectoderm; orbito-sphenoid; and submandibular gland primordium. Orthologous to human SRFBP1 (serum response factor binding protein 1). [provided by Alliance of Genome Resources, Jul 2025] | 18 | 52598703 | 52625005 | Mouse | 67 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16556074 | AC010132.2 | serine/threonine kinase receptor associated protein (STRAP) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16553184 | AC010878.1 | serine/threonine kinase receptor associated protein (STRAP) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 12113160 | DERA | deoxyribose-phosphate aldolase | ENCODES a protein that exhibits deoxyribose-phosphate aldolase activity (inferred); lyase activity (inferred); INVOLVED IN deoxyribonucleoside catabolic process (inferred); deoxyribonucleotide catabolic process (inferred); deoxyribose phosphate catabolic process (inferred); PARTICIPATES IN pentose p hosphate pathway; ribose 5-phosphate isomerase deficiency pathway; transaldolase deficiency pathway; ASSOCIATED WITH COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 27 | 30675225 | 30741202 | Dog | 23 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |