Stradb Gene Search Result

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14 records found for search term Stradb

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1350818	STRADB	STE20 related adaptor beta	This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threo ... (more) nine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]	2	201451740	201480846	Human	84	symbol , COSMIC , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
1557735	Stradb	STE20-related kinase adaptor beta	Predicted to enable protein serine/threonine kinase activator activity. Acts upstream of or within JNK cascade; cell morphogenesis; and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand. Predicted to be located in aggresome; cytosol; and nucleus. Predicted to be part ... (more) of serine/threonine protein kinase complex. Is expressed in central nervous system; liver; and retina. Orthologous to human STRADB (STE20 related adaptor beta). [provided by Alliance of Genome Resources, Jul 2025]	1	59012681	59034281	Mouse	97	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1559449	Stradb	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8 ... (more) -tetrachlorodibenzodioxine; bisphenol A	9	67908277	67927224	Rat	86	symbol , PhenoGen	gene, protein-coding, VALIDATED [RefSeq]
8916318	Stradb	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)	NW_004955403	181120	198882	Chinchilla	15	symbol	gene, protein-coding, MODEL [RefSeq]
12015337	STRADB	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)	2B	88705840	88735511	Bonobo	24	symbol	gene, protein-coding, MODEL [RefSeq]
12085926	STRADB	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)	37	10521643	10557611	Dog	24	symbol	gene, protein-coding, MODEL [RefSeq]
12669527	Stradb	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)	NW_004936726	709037	728696	Squirrel	24	symbol	gene, protein-coding, MODEL [RefSeq]
18925843	Stradb	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog)				Naked Mole-Rat	22	symbol	gene, protein-coding, MODEL [RefSeq]
626002903	Stradb	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)				Black Rat	15	symbol	gene, protein-coding, MODEL [RefSeq]
14258680	STRADB	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)				Pig	25	symbol	gene, protein-coding, MODEL [RefSeq]
155234957	stradb						Tropical Clawed Frog		symbol	gene, null
18499437	STRADB	STE20 related adaptor beta	ENCODES a protein that exhibits protein kinase activity (ortholog); INVOLVED IN activation of protein kinase activity (ortholog); cell morphogenesis (ortholog); JNK cascade (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleoplasm (inferred)				Green Monkey	24	symbol	gene, protein-coding, MODEL [RefSeq]
155234958	stradb.L						African Clawed Frog		symbol	gene, null
4144673	STRADBP1	STE20-related kinase adaptor beta pseudogene 1	INTERACTS WITH temozolomide	7	150511976	150514047	Human	1	symbol , COSMIC , Human Proteome Map	gene, pseudo, INFERRED [RefSeq]