St14 Gene Search Result

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14 records found for search term St14

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
69288	St14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity; serine-type endopeptidase activity (ortholog); INVOLVED IN protein catabolic process; epithelial cell morphogenesis involved in placental branching (ortholog); keratinocyte differentiation (ortholog); ASSOCIATED WITH autosomal recessive ... (more) congenital ichthyosis 11 (ortholog); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane; extracellular space; external side of plasma membrane (ortholog); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine	8	37798994	37839881	Rat	182	symbol , PhenoGen , name	gene, protein-coding, PROVISIONAL [RefSeq]
733374	ST14	ST14 transmembrane serine protease matriptase	The protein encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte g ... (more) rowth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis. [provided by RefSeq, Jul 2008]	11	130159782	130210362	Human	210	symbol , COSMIC , name , Human Proteome Map	gene, protein-coding, REVIEWED [RefSeq]
733375	St14	suppression of tumorigenicity 14 (colon carcinoma)	Enables serine-type endopeptidase activity. Involved in proteolysis. Acts upstream of or within epithelial cell morphogenesis involved in placental branching and neural tube closure. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including al ... (more) imentary system; brain; early conceptus; genitourinary system; and sensory organ. Used to study Sjogren's syndrome. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 11. Orthologous to human ST14 (ST14 transmembrane serine protease matriptase). [provided by Alliance of Genome Resources, Jul 2025]	9	30999886	31043138	Mouse	293	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
8863476	St14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); keratinocyte differentiation (ortholog); neural tube closure (ortholog); ASSOCIATED WITH aut ... (more) osomal recessive congenital ichthyosis 11 (ortholog); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog)	NW_004955412	31091313	31129050	Chinchilla	39	symbol , name	gene, protein-coding, MODEL [RefSeq]
11847165	ST14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); neural tube closure (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholo ... (more) g); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); extracellular space (ortholog)	11	125001771	125021371	Bonobo	52	symbol , name	gene, protein-coding, MODEL [RefSeq]
12092181	ST14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); neural tube closure (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholo ... (more) g); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); extracellular space (ortholog)	5	4652493	4666728	Dog	51	symbol , name	gene, protein-coding, MODEL [RefSeq]
12533121	St14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); neural tube closure (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholo ... (more) g); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); extracellular space (ortholog)	NW_004936572	2137820	2182674	Squirrel	49	symbol , name	gene, protein-coding, MODEL [RefSeq]
155251717	st14						Tropical Clawed Frog		symbol	gene, null
13903685	ST14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); neural tube closure (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholo ... (more) g); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); extracellular space (ortholog); INTERACTS WITH deoxynivalenol				Pig	54	symbol , name	gene, protein-coding, MODEL [RefSeq]
18645245	ST14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); neural tube closure (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholo ... (more) g); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); extracellular space (ortholog)				Green Monkey	49	symbol , name	gene, protein-coding, MODEL [RefSeq]
626115735	St14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type endopeptidase activity (ortholog); serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); keratinocyte differentiation (ortholog); neural tube closure (ortholog); ASSOCIATED WITH aut ... (more) osomal recessive congenital ichthyosis 11 (ortholog); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog)				Black Rat	39	symbol , name	gene, protein-coding, MODEL [RefSeq]
18906798	St14	ST14 transmembrane serine protease matriptase	ENCODES a protein that exhibits serine-type peptidase activity (ortholog); INVOLVED IN epithelial cell morphogenesis involved in placental branching (ortholog); neural tube closure (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH autosomal recessive congenital ichthyosis 11 (ortholo ... (more) g); Breast Neoplasms (ortholog); COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); extracellular space (ortholog)				Naked Mole-Rat	49	symbol , name	gene, protein-coding, MODEL [RefSeq]
155232875	st14.L						African Clawed Frog		symbol	gene, null
155254050	st14.S						African Clawed Frog		symbol	gene, null