| 1345309 | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of cell migration and regulation of postsynapse assembly. Is active in postsynapse. [provided by Alliance of Genome Resources, Jul 2025] | 3 | 8980591 | 9363027 | Human | 139 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1557097 | Srgap3 | SLIT-ROBO Rho GTPase activating protein 3 | Predicted to enable GTPase activator activity. Involved in regulation of postsynapse assembly. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Used to study schi zophrenia. Orthologous to human SRGAP3 (SLIT-ROBO Rho GTPase activating protein 3). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 112694932 | 112924466 | Mouse | 154 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1563152 | Srgap3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og); postsynapse (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; alpha-Zearalanol | 4 | 147391082 | 147626407 | Rat | 134 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 9015459 | Srgap3 | SLIT-ROBO Rho GTPase activating protein 3 | INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog) | NW_004955561 | 612152 | 835209 | Chinchilla | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11719670 | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og) | 3 | 8935179 | 9315264 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12388665 | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og) | 20 | 8894150 | 9147060 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12682733 | Srgap3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og) | NW_004936602 | 3770323 | 4020043 | Squirrel | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14124533 | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og); INTERACTS WITH deoxynivalenol | | | | Pig | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18740140 | SRGAP3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og) | | | | Green Monkey | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18926899 | Srgap3 | SLIT-ROBO Rho GTPase activating protein 3 | ENCODES a protein that exhibits GTPase activator activity (inferred); INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (orthol og); postsynapse (ortholog) | | | | Naked Mole-Rat | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405859335 | srgap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 405864417 | srgap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 405864697 | srgap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 405865119 | srgap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598152273 | srgap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 598152470 | srgap3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626137101 | Srgap3 | SLIT-ROBO Rho GTPase activating protein 3 | INVOLVED IN regulation of postsynapse assembly (ortholog); ASSOCIATED WITH Chromosome 3, Monosomy 3p25 (ortholog); intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog) | | | | Black Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 405857723 | srgap3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405859336 | srgap3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861435 | srgap3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864416 | srgap3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626187266 | srgap3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 405860958 | srgap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405861433 | srgap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405864696 | srgap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 405865120 | srgap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626171130 | srgap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626180341 | srgap3.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6480826 | SRGAP3-AS1 | SRGAP3 antisense RNA 1 | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna |
| 5144597 | SRGAP3-AS2 | SRGAP3 antisense RNA 2 | | 3 | 9192493 | 9194453 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 5144719 | SRGAP3-AS3 | SRGAP3 antisense RNA 3 | | 3 | 9216895 | 9219508 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 6481222 | SRGAP3-AS4 | SRGAP3 antisense RNA 4 | INTERACTS WITH propofol | 3 | 9249756 | 9257507 | Human | 1 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1603684 | SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 | This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus its elf is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Jul 2014] | 1 | 206203541 | 206464436 | Human | 155 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1614456 | Srgap2 | SLIT-ROBO Rho GTPase activating protein 2 | Enables GTPase activator activity; protein homodimerization activity; and small GTPase binding activity. Involved in several processes, including filopodium assembly; nervous system development; and positive regulation of GTPase activity. Located in cytosol; phagocytic vesicle; and postsynaptic memb rane. Is active in dendritic spine; glutamatergic synapse; and postsynaptic density. Is expressed in several structures, including central nervous system; dorsal root ganglion; heart; and sensory organ. Orthologous to human SRGAP2 (SLIT-ROBO Rho GTPase activating protein 2). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 131212989 | 131455269 | Mouse | 170 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 16572702 | AC037193.1 | novel transcript, antisense to SRGAP3 | | | | | Human | | name | gene, lncrna |