| 708584 | Spon2 | spondin 2 | ENCODES a protein that exhibits signaling receptor binding; antigen binding (ortholog); lipopolysaccharide binding (ortholog); INVOLVED IN cell adhesion; cellular response to platelet-derived growth factor stimulus; vascular associated smooth muscle cell proliferation; ASSOCIATED WITH abnormal vascu lar wound healing; ASSOCIATED WITH Neointima; basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 14 | 81713070 | 81742510 | Rat | 203 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 731918 | Spon2 | spondin 2, extracellular matrix protein | Enables antigen binding activity and lipopolysaccharide binding activity. Acts upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular matrix and extracellular space. Orthologous to human SPON2 (spondin 2). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 33370862 | 33375596 | Mouse | 214 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1352786 | SPON2 | spondin 2 | Predicted to enable antigen binding activity; lipopolysaccharide binding activity; and metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular exosome. Biomarker of meningioma. [provided by Alliance of Genome Resources, Apr 2025] | 4 | 1166932 | 1208844 | Human | 205 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 8930079 | Spon2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | NW_004955514 | 598840 | 603390 | Chinchilla | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11840372 | SPON2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular space (ortholog) | 4 | 1309473 | 1351529 | Bonobo | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12198723 | SPON2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | 3 | 91411245 | 91421245 | Dog | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12647465 | Spon2 | spondin 2 | ENCODES a protein that exhibits signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery In juries (ortholog); meningioma (ortholog); FOUND IN extracellular matrix (inferred); extracellular space (inferred) | NW_004936477 | 22087450 | 22093677 | Squirrel | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625899135 | Spon2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | | | | Black Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14075088 | SPON2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular matrix (ortholog); extracellular space (ortholog) | | | | Pig | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155235340 | spon2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18906283 | Spon2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular space (ortholog) | | | | Naked Mole-Rat | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18551865 | SPON2 | spondin 2 | ENCODES a protein that exhibits antigen binding (ortholog); lipopolysaccharide binding (ortholog); signaling receptor binding (ortholog); INVOLVED IN cell adhesion (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to platelet-derived growth factor stimulus (ortholog); ASSOCIATED WITH basal cell carcinoma (ortholog); Carotid Artery Injuries (ortholog); meningioma (ortholog); FOUND IN extracellular space (ortholog) | | | | Green Monkey | 41 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238069 | spon2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155235339 | spon2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16566736 | SPON2-AS1 | SPON2 antisense RNA 1 | | | | | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, lncrna |
| 617256066 | SPON2-AS1 | SPON2 antisense RNA 1 | | | | | Human | | symbol , GTEx , COSMIC , name , Human Proteome Map | gene, ncrna |
| 329333021 | Spon2em1Holi | spondin 2; TALEN induced mutant1, Holi | ASSOCIATED WITH abnormal vascular wound healing; ASSOCIATED WITH Neointima | | | | Rat | 2 | symbol , description | gene, allele |