| 1307811 | Spc25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); chromosome segregation (ortholog); mitotic spindle organization (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); kinetochore (ortholog); Ndc80 complex (ortholog); INTERACTS WITH 1-n aphthyl isothiocyanate; 17alpha-ethynylestradiol; 17beta-estradiol | 3 | 74337872 | 74396825 | Rat | 222 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1606531 | SPC25 | SPC25 component of NDC80 kinetochore complex | This gene encodes a protein that may be involved in kinetochore-microtubule interaction and spindle checkpoint activity. [provided by RefSeq, Jul 2008] | 2 | 168861521 | 168890430 | Human | 218 | symbol , old_gene_name , COSMIC , name , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 1623224 | Spc25 | SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) | This gene encodes a component of the kinetochore-associated NDC80 protein complex, which is required for the mitotic spindle checkpoint and for microtubule-kinetochore attachment. During meiosis in mouse, the protein localizes to the germinal vesicle and then is associated with the chromosomes follo wing germinal vesicle breakdown. Knockdown of this gene in oocytes results in precocious polar body extrusion, chromosome misalignment and aberrant spindle formation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] | 2 | 69009753 | 69036583 | Mouse | 234 | symbol , old_gene_name , PhenoGen , name | gene, protein-coding, REVIEWED [RefSeq] |
| 8918766 | Spc25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); chromosome segregation (ortholog); mitotic spindle organization (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); kinetochore (ortholog); Ndc80 complex (ortholog) | NW_004955449 | 5533464 | 5556341 | Chinchilla | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12043094 | SPC25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (inferred); cell division (inferred); chromosome segregation (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN chromosome, centromeric region (inferred); cytosol (inferred); kinetochore (inferred) | 2B | 56148325 | 56190851 | Bonobo | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12208397 | SPC25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (inferred); cell division (inferred); chromosome segregation (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN chromosome, centromeric region (inferred); cytosol (inferred); kinetochore (inferred) | 36 | 13697389 | 13710367 | Dog | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 12621314 | Spc25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (inferred); cell division (inferred); chromosome segregation (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN chromosome, centromeric region (inferred); cytosol (inferred); kinetochore (inferred) | NW_004936469 | 10628235 | 10652168 | Squirrel | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 18909114 | Spc25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); mitotic spindle organization (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); outer kinetochore (ortholog) | | | | Naked Mole-Rat | 20 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 20867147 | SPC25 | SPC25 component of NDC80 kinetochore complex | | | | | Green Monkey | | symbol , name | gene, protein-coding |
| 13848622 | SPC25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (inferred); cell division (inferred); chromosome segregation (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN chromosome, centromeric region (inferred); cytosol (inferred); kinetochore (inferred); INTERACTS WITH d eoxynivalenol; resveratrol | | | | Pig | 25 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 625941597 | Spc25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (ortholog); chromosome segregation (ortholog); mitotic spindle organization (ortholog); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN cytosol (ortholog); kinetochore (ortholog); Ndc80 complex (ortholog) | | | | Black Rat | 13 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155254828 | spc25 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18580804 | SPC25 | SPC25 component of NDC80 kinetochore complex | INVOLVED IN attachment of spindle microtubules to kinetochore (inferred); cell division (inferred); chromosome segregation (inferred); ASSOCIATED WITH hepatocellular carcinoma (ortholog); FOUND IN chromosome, centromeric region (inferred); cytosol (inferred); kinetochore (inferred) | | | | Green Monkey | 23 | symbol , old_gene_name , name | gene, protein-coding, MODEL [RefSeq] |
| 155260050 | spc25.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 12238582 | SPCS2 | signal peptidase complex subunit 2 | ENCODES a protein that exhibits peptidase activity (inferred); INVOLVED IN signal peptide processing (inferred); FOUND IN signal peptidase complex | 21 | 23485367 | 23510249 | Dog | 15 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |