| 1309778 | Snx13 | sorting nexin 13 | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); INVOLVED IN intracellular protein transport (ortholog); positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic recept or beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 6 | 57478139 | 57589624 | Rat | 73 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1320299 | SNX13 | sorting nexin 13 | This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008] | 7 | 17790761 | 17940494 | Human | 72 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320300 | Snx13 | sorting nexin 13 | Predicted to enable phosphatidylinositol binding activity. Predicted to be involved in intracellular protein transport and positive regulation of GTPase activity. Predicted to be located in early endosome membrane. Predicted to be active in early endosome. Is expressed in embryo. Orthologous to huma n SNX13 (sorting nexin 13). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 35097191 | 35197479 | Mouse | 90 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8930779 | Snx13 | sorting nexin 13 | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); INVOLVED IN intracellular protein transport (ortholog); positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic recept or beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (ortholog) | NW_004955410 | 20792659 | 20925907 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12049833 | SNX13 | sorting nexin 13 | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic receptor beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (inferred); early endosome membrane (inferred) | 7 | 18444092 | 18593950 | Bonobo | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12061685 | SNX13 | sorting nexin 13 | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic receptor beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (inferred); early endosome membrane (inferred); endosome membrane (inferred) | 14 | 32173630 | 32291039 | Dog | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12709160 | Snx13 | sorting nexin 13 | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic receptor beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (inferred); early endosome membrane (inferred) | NW_004936546 | 4127333 | 4270107 | Squirrel | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18686147 | SNX13 | sorting nexin 13 | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic receptor beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (inferred); early endosome membrane (inferred) | | | | Green Monkey | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18926970 | Snx13 | sorting nexin 13 | ENCODES a protein that exhibits phosphatidylinositol-3-phosphate binding (ortholog); INVOLVED IN intracellular protein transport (ortholog); positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic receptor beta; G protein mediated signaling pat hway via Galphas family; FOUND IN early endosome (inferred); early endosome membrane (inferred) | | | | Naked Mole-Rat | 12 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246049 | snx13 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626068900 | Snx13 | sorting nexin 13 | ENCODES a protein that exhibits phosphatidylinositol binding (ortholog); phosphatidylinositol-3-phosphate binding (ortholog); INVOLVED IN intracellular protein transport (ortholog); positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic recept or beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14292555 | SNX13 | sorting nexin 13 | ENCODES a protein that exhibits lipid binding (inferred); phosphatidylinositol binding (inferred); phosphatidylinositol-3-phosphate binding (inferred); INVOLVED IN positive regulation of GTPase activity (ortholog); PARTICIPATES IN epinephrine signaling pathway via adrenergic receptor beta; G protein mediated signaling pathway via Galphas family; FOUND IN early endosome (inferred); early endosome membrane (inferred); endosome membrane (inferred) | | | | Pig | 15 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155246050 | snx13.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155250894 | snx13.S | | | | | | African Clawed Frog | | symbol | gene, null |
