| 621301 | Snrpb | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits U1 snRNP binding; U2 snRNP binding; histone pre-mRNA DCP binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); protein methylation (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; systemic lupus erythematosu s pathway; ASSOCIATED WITH cerebrocostomandibular syndrome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUND IN U1 snRNP; U2 snRNP; catalytic step 2 spliceosome (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 6-propyl-2-thiouracil; amitrole | 3 | 137824870 | 137832479 | Rat | 197 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733493 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. A utoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene. [provided by RefSeq, Jul 2008] | 20 | 2461642 | 2470789 | Human | 327 | symbol , COSMIC , Human Proteome Map , old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 733494 | Snrpb | small nuclear ribonucleoprotein B | Enables histone pre-mRNA DCP binding activity. Predicted to be involved in spliceosomal snRNP assembly. Predicted to act upstream of or within protein methylation. Located in cytoplasm and nucleus. Part of histone pre-mRNA 3'end processing complex. Is expressed in several structures, including branc hial arch; central nervous system; genitourinary system; limb; and sensory organ. Used to study cerebrocostomandibular syndrome. Human ortholog(s) of this gene implicated in cerebrocostomandibular syndrome and mixed connective tissue disease. Orthologous to human SNRPB (small nuclear ribonucleoprotein polypeptides B and B1). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 130013560 | 130031184 | Mouse | 278 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8808246 | Snrpb | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits histone pre-mRNA DCP binding (ortholog); RNA binding (ortholog); telomerase RNA binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); protein methylation (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSO CIATED WITH cerebrocostomandibular syndrome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955415 | 13522638 | 13530725 | Chinchilla | 65 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12043493 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits U1 snRNP binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN protein methylation (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH cerebrocostomandibular syndrome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUN D IN U1 snRNP (ortholog); U2 snRNP (ortholog) | 20 | 2571393 | 2580642 | Bonobo | 71 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12201622 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits histone pre-mRNA DCP binding (ortholog); telomerase RNA binding (ortholog); U1 snRNP binding (ortholog); INVOLVED IN protein methylation (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH cerebrocostomandibular syn drome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); histone pre-mRNA 3'end processing complex (ortholog) | 24 | 18673975 | 18683315 | Dog | 72 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12530564 | Snrpb | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits histone pre-mRNA DCP binding (ortholog); U1 snRNP binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN protein methylation (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH cerebrocostomandibular syndrome (ortholog); Desbuquois dysplasia (orthol og); Disease Progression (ortholog); FOUND IN histone pre-mRNA 3'end processing complex (ortholog); U1 snRNP (ortholog); U2 snRNP (ortholog) | NW_004936485 | 16142231 | 16161761 | Squirrel | 78 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14230658 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES an ncrna that exhibits histone pre-mRNA DCP binding (ortholog); telomerase RNA binding (ortholog); U1 snRNP binding (ortholog); INVOLVED IN protein methylation (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH cerebrocostomandibular synd rome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); histone pre-mRNA 3'end processing complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 73 | symbol | gene, ncrna, MODEL [RefSeq] |
| 18759898 | SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits U1 snRNP binding (ortholog); U2 snRNP binding (ortholog); INVOLVED IN protein methylation (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH cerebrocostomandibular syndrome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUN D IN U1 snRNP (ortholog); U2 snRNP (ortholog) | | | | Green Monkey | 70 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18926349 | Snrpb | small nuclear ribonucleoprotein polypeptides B and B1 | ENCODES a protein that exhibits histone pre-mRNA DCP binding (ortholog); telomerase RNA binding (ortholog); U1 snRNP binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); protein methylation (ortholog); spliceosomal snRNP assembly (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH cerebrocostomandibular syndrome (ortholog); Desbuquois dysplasia (ortholog); Disease Progression (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Naked Mole-Rat | 68 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231537 | snrpb | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 155237585 | snrpb.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155233726 | snrpb.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7580217 | Snrpb-ps1 | small nuclear ribonucleoprotein polypeptides B and B1, pseudogene 1 | | 1 | 124716586 | 124717485 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 2322482 | Snrpb-ps2 | small nuclear ribonucleoprotein polypeptides B and B1, pseudogene 2 | | 4 | 77497730 | 77498423 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1310194 | Snrpb2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding; INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN small nuclear ribonucleoprotein complex; catalytic s tep 2 spliceosome (ortholog); nuclear speck (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; finasteride | 3 | 150852814 | 150862364 | Rat | 105 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320950 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 | The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the en coded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] | 20 | 16730026 | 16742564 | Human | 122 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1320951 | Snrpb2 | U2 small nuclear ribonucleoprotein B | Predicted to enable U1 snRNA binding activity and snRNP binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytoplasmic ribonucleoprotein granule; fibrillar center; and nuclear speck. Predicted to be part of U1 snRNP; U2-type catalytic step 2 spli ceosome; and U2-type precatalytic spliceosome. Is expressed in 8-cell stage embryo; central nervous system; olfactory epithelium; submandibular gland primordium; and vibrissa. Human ortholog(s) of this gene implicated in connective tissue disease. Orthologous to human SNRPB2 (small nuclear ribonucleoprotein polypeptide B2). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 142904989 | 142913972 | Mouse | 126 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 8888737 | Snrpb2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog) | NW_004955415 | 25880013 | 25889295 | Chinchilla | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11862429 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog ); FOUND IN small nuclear ribonucleoprotein complex (ortholog) | 20 | 16690562 | 16701964 | Bonobo | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12072605 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA processing (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN catalytic step 2 spliceosome (o rtholog); nuclear speck (ortholog); small nuclear ribonucleoprotein complex (ortholog) | 24 | 6106217 | 6117369 | Dog | 38 | symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 12576503 | Snrpb2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); small nuclear ribonucleoprotein complex (ortholog) | NW_004936485 | 3296350 | 3305985 | Squirrel | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14104177 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog ); FOUND IN small nuclear ribonucleoprotein complex (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 42 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18738770 | SNRPB2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA processing (inferred); mRNA splicing, via spliceosome (inferred); RNA splicing (inferred); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog ); FOUND IN small nuclear ribonucleoprotein complex (ortholog) | | | | Green Monkey | 39 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18912381 | Snrpb2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); small nuclear ribonucleoprotein complex (ortholog) | | | | Naked Mole-Rat | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155239307 | snrpb2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626146260 | Snrpb2 | small nuclear ribonucleoprotein polypeptide B2 | ENCODES a protein that exhibits snRNP binding (ortholog); INVOLVED IN mRNA splicing, via spliceosome (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIATED WITH connective tissue disease (ortholog); disease of cellular proliferation (ortholog); FOUND IN catalytic step 2 spliceosome (ortholog); nuclear speck (ortholog); nucleus (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 4109592 | SNRPBP1 | small nuclear ribonucleoprotein polypeptides B and B1 pseudogene 1 | | 7 | 80377554 | 80377835 | Human | | symbol , COSMIC , Human Proteome Map | gene, pseudo, VALIDATED [RefSeq] |
| 155244120 | snrpb2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155239308 | snrpb2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 16557553 | SNRPB2P1 | SNRPB2 pseudogene 1 | | 3 | 59535863 | 59536415 | Human | | symbol , old_gene_name , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |
| 1562613 | Snrpb2-ps1 | small nuclear ribonucleoprotein polypeptide B2, pseudogene 1 | | 13 | 50582255 | 50583042 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1321287 | HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRN A processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. This gene has been described to generate two alternatively spliced transcript variants which encode different isoforms. [provided by RefSeq, Jul 2008] | 7 | 26189927 | 26200746 | Human | 391 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 16554233 | AL034428.1 | novel transcript, antisense to SNRPB2 | | | | | Human | | name | gene, lncrna |
| 16560234 | AC022690.1 | small nuclear ribonucleoprotein polypeptide B' (SNRPB2) pseudogene | | 8 | 13909232 | 13909784 | Human | | name | gene, pseudo, INFERRED [RefSeq] |
| 16552394 | AL603766.1 | small nuclear ribonucleoprotein polypeptide B'' (SNRPB2) pseudogene | | | | | Human | | name | gene, processed_pseudogene |
| 16554481 | AL133384.1 | pseudogene similar to part of small nuclear ribonucleoprotein polypeptide B (SNRPB2) | | | | | Human | | name | gene, processed_pseudogene |