| 69338 | Slc22a6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits antiporter activity; prostaglandin transmembrane transporter activity; transmembrane transporter activity; INVOLVED IN metanephric proximal tubule development; organic anion transport; prostaglandin transport; PARTICIPATES IN multispecific organic anion transporter me diated transport pathway; amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN caveola; protein-containing complex; basal plasma membrane (ortholog); INTERACTS WITH (-)-citrinin; 1-naphthyl isothiocyanate; 2,2,2-tetramine | 1 | 214951493 | 214960317 | Rat | 376 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 619572 | SLC22A6 | solute carrier family 22 member 6 | The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 11 | 62976597 | 62984967 | Human | 352 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 619573 | Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | Enables antiporter activity and organic anion transmembrane transporter activity. Involved in organic anion transport and renal tubular secretion. Acts upstream of or within monoatomic anion transport. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain ; genitourinary system; sensory organ; and skeleton. Orthologous to human SLC22A6 (solute carrier family 22 member 6). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 8595360 | 8605663 | Mouse | 381 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9025630 | Slc22a6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits alpha-ketoglutarate transmembrane transporter activity (ortholog); antiporter activity (ortholog); prostaglandin transmembrane transporter activity (ortholog); INVOLVED IN alpha-ketoglutarate transport (ortholog); metanephric proximal tubule development (ortholog); mo noatomic anion transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog) | NW_004955599 | 302026 | 307503 | Chinchilla | 64 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11913350 | SLC22A6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits antiporter activity (ortholog); secondary active transmembrane transporter activity (ortholog); INVOLVED IN metanephric proximal tubule development (ortholog); monoatomic anion transport (ortholog); organic anion transport (ortholog); PARTICIPATES IN amiloride pharmac odynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN caveola (ortholog); protein-containing complex (ortholog) | 11 | 58328476 | 58336887 | Bonobo | 55 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12152101 | SLC22A6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits antiporter activity (ortholog); secondary active transmembrane transporter activity (ortholog); INVOLVED IN metanephric proximal tubule development (ortholog); monoatomic anion transport (ortholog); organic anion transport (ortholog); PARTICIPATES IN amiloride pharmac odynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN caveola (ortholog); protein-containing complex (ortholog); INTERACTS WITH 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; indoxyl sulfate; lansoprazole | 18 | 53736669 | 53745001 | Dog | 60 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12524487 | Slc22a6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits antiporter activity (ortholog); secondary active transmembrane transporter activity (ortholog); INVOLVED IN metanephric proximal tubule development (ortholog); monoatomic anion transport (ortholog); organic anion transport (ortholog); PARTICIPATES IN amiloride pharmac odynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN caveola (ortholog); protein-containing complex (ortholog) | NW_004936581 | 348719 | 356246 | Squirrel | 55 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155247010 | slc22a6 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626045545 | Slc22a6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits alpha-ketoglutarate transmembrane transporter activity (ortholog); antiporter activity (ortholog); prostaglandin transmembrane transporter activity (ortholog); INVOLVED IN alpha-ketoglutarate transport (ortholog); metanephric proximal tubule development (ortholog); mo noatomic anion transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog) | | | | Black Rat | 64 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13892476 | SLC22A6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits alpha-ketoglutarate transmembrane transporter activity (ortholog); antiporter activity (ortholog); prostaglandin transmembrane transporter activity (ortholog); INVOLVED IN alpha-ketoglutarate transport (ortholog); metanephric proximal tubule development (ortholog); mo noatomic anion transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog) | | | | Pig | 69 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18470533 | SLC22A6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits antiporter activity (ortholog); secondary active transmembrane transporter activity (ortholog); INVOLVED IN metanephric proximal tubule development (ortholog); monoatomic anion transport (ortholog); organic anion transport (ortholog); PARTICIPATES IN amiloride pharmac odynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN caveola (ortholog); protein-containing complex (ortholog) | | | | Green Monkey | 55 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18929579 | Slc22a6 | solute carrier family 22 member 6 | ENCODES a protein that exhibits alpha-ketoglutarate transmembrane transporter activity (ortholog); antiporter activity (ortholog); prostaglandin transmembrane transporter activity (ortholog); INVOLVED IN alpha-ketoglutarate transport (ortholog); metanephric proximal tubule development (ortholog); mo noatomic anion transport (ortholog); PARTICIPATES IN amiloride pharmacodynamics pathway; bendroflumethiazide pharmacodynamics pathway; bumetanide pharmacodynamics pathway; ASSOCIATED WITH calcinosis (ortholog); FOUND IN basal plasma membrane (ortholog); basolateral plasma membrane (ortholog); caveola (ortholog) | | | | Naked Mole-Rat | 62 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155241120 | slc22a6.S | | | | | | African Clawed Frog | | symbol | gene, null |