| 620603 | Slc16a3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate:proton symporter activity; lactate transmembrane transporter activity (ortholog); pyruvate transmembrane transporter activity (ortholog); INVOLVED IN plasma membrane lactate transport; lactate transmembrane transport (ortholog); pyruvate catabolic process (ort holog); ASSOCIATED WITH Breast Neoplasms (ortholog); Stomach Neoplasms (ortholog); FOUND IN plasma membrane; apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,4-D; 6-propyl-2-thiouracil | 10 | 106712328 | 106756168 | Rat | 241 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 731750 | SLC16A3 | solute carrier family 16 member 3 | Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kineti cs, which are related to the metabolic requirements of the tissues in which it is found. The MCTs, which include MCT1 (SLC16A1; MIM 600682) and MCT2 (SLC16A7; MIM 603654), are characterized by 12 predicted transmembrane domains (Price et al., 1998 [PubMed 9425115]).[supplied by OMIM, Mar 2008] | 17 | 82217934 | 82240086 | Human | 239 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1550543 | Slc16a3 | solute carrier family 16 (monocarboxylic acid transporters), member 3 | Enables lactate transmembrane transporter activity. Involved in pyruvate catabolic process. Is active in plasma membrane. Is expressed in several structures, including alimentary system; brain; early conceptus; gonad; and skeleton. Orthologous to human SLC16A3 ( solute carrier family 16 member 3). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 120839310 | 120849826 | Mouse | 266 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8818691 | Slc16a3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (ortholog); lactate:proton symporter activity (ortholog); pyruvate transmembrane transporter activity (ortholog); INVOLVED IN lactate transmembrane transport (ortholog); plasma membrane lactate transport (ortholog); pyruvate catabolic process (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); lateral plasma membrane (ortholog) | NW_004955506 | 935783 | 945014 | Chinchilla | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11886166 | SLC16A3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (inferred); lactate:proton symporter activity (inferred); monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN plasma membrane lactate transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog ); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lateral plasma membrane (inferred) | 17 | 76638030 | 76649159 | Bonobo | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12074185 | SLC16A3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (inferred); lactate:proton symporter activity (inferred); monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN plasma membrane lactate transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog ); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lateral plasma membrane (inferred) | 9 | 109557 | 119179 | Dog | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12647607 | Slc16a3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (inferred); lactate:proton symporter activity (inferred); monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN plasma membrane lactate transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog ); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lateral plasma membrane (inferred) | NW_004936594 | 5715234 | 5721343 | Squirrel | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625920951 | Slc16a3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (ortholog); lactate:proton symporter activity (ortholog); pyruvate transmembrane transporter activity (ortholog); INVOLVED IN lactate transmembrane transport (ortholog); plasma membrane lactate transport (ortholog); pyruvate catabolic process (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (ortholog); basolateral plasma membrane (ortholog); lateral plasma membrane (ortholog) | | | | Black Rat | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242589 | slc16a3 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18739208 | SLC16A3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (inferred); lactate:proton symporter activity (inferred); monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN plasma membrane lactate transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog ); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lateral plasma membrane (inferred) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18921108 | Slc16a3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (inferred); lactate:proton symporter activity (inferred); monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN plasma membrane lactate transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog ); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lateral plasma membrane (inferred) | | | | Naked Mole-Rat | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14161817 | SLC16A3 | solute carrier family 16 member 3 | ENCODES a protein that exhibits lactate transmembrane transporter activity (inferred); lactate:proton symporter activity (inferred); monocarboxylic acid transmembrane transporter activity (inferred); INVOLVED IN plasma membrane lactate transport (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog ); Stomach Neoplasms (ortholog); FOUND IN apical plasma membrane (inferred); basolateral plasma membrane (inferred); lateral plasma membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155231619 | slc16a3.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155242590 | slc16a3.S | | | | | | African Clawed Frog | | symbol | gene, null |