| 3655 | Sell | selectin L | ENCODES a protein that exhibits glycolipid binding; calcium ion binding (ortholog); cell adhesion molecule binding (ortholog); INVOLVED IN cellular response to interleukin-8; heterotypic cell-cell adhesion; negative regulation of leukocyte tethering or rolling; ASSOCIATED WITH abdominal aortic aneur ysm; alcoholic hepatitis; colitis; FOUND IN cell surface; extracellular space; external side of plasma membrane (ortholog); INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | 13 | 78950100 | 78969604 | Rat | 254 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 737030 | Sell | selectin, lymphocyte | Enables cell adhesion molecule binding activity. Acts upstream of or within response to ATP. Located in external side of plasma membrane. Is expressed in brain; brainstem; submandibular gland epithelium; and testis. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in Crohn's disease; IgA glomerulonephritis; and ulcerative colitis. Orthologous to human SELL (selectin L). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 163889556 | 163908354 | Mouse | 348 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1342543 | SELL | selectin L | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding a nd subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] | 1 | 169690667 | 169711620 | Human | 249 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8735023 | Sell | selectin L | ENCODES a protein that exhibits calcium ion binding (ortholog); cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN calcium-dependent cell-cell adhesion (ortholog); cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | NW_004955462 | 7591997 | 7611408 | Chinchilla | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11733069 | SELL | selectin L | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); negative regulation of leukocyte tethering or rolling (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | 1 | 145173700 | 145194927 | Bonobo | 78 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12131890 | SELL | selectin L | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); negative regulation of leukocyte tethering or rolling (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | 7 | 28906752 | 28927959 | Dog | 83 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12632164 | Sell | selectin L | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); negative regulation of leukocyte tethering or rolling (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | NW_004936481 | 17022421 | 17032105 | Squirrel | 76 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18905751 | Sell | selectin L | ENCODES a protein that exhibits calcium ion binding (ortholog); cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); leukocyte tethering or rolling (ortholog); ASSOCIATED WITH a bdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | | | | Naked Mole-Rat | 74 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626146872 | Sell | selectin L | ENCODES a protein that exhibits calcium ion binding (ortholog); cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN calcium-dependent cell-cell adhesion (ortholog); cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | | | | Black Rat | 69 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18603109 | SELL | selectin L | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); negative regulation of leukocyte tethering or rolling (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | | | | Green Monkey | 78 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288083453 | sell | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14075140 | SELL | selectin L | ENCODES a protein that exhibits cell adhesion molecule binding (ortholog); glycolipid binding (ortholog); INVOLVED IN cellular response to interleukin-8 (ortholog); heterotypic cell-cell adhesion (ortholog); negative regulation of leukocyte tethering or rolling (ortholog); ASSOCIATED WITH abdominal aortic aneurysm (ortholog); alcohol use disorder (ortholog); alcoholic hepatitis (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog) | | | | Pig | 76 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 287026918 | sell.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626172752 | sell.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1349040 | KIRREL1 | kirre like nephrin family adhesion molecule 1 | NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008] | 1 | 157993645 | 158100262 | Human | 110 | description | gene, protein-coding, VALIDATED [RefSeq] |