Selk Gene Search Result

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9 records found for search term Selk

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
8827726	LOC102027036	selenoprotein K-like		NW_004955451	10839662	10840425	Chinchilla		old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
1303129	Selenok	selenoprotein K	INVOLVED IN calcium ion transport (ortholog); intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ortholog); macrophage derived foam cell differentiation (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog); INTERACTS WITH 2, ... (more) 2',4,4'-Tetrabromodiphenyl ether; 4,4'-sulfonyldiphenol; acrylamide	16	5158601	5167183	Rat	121	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1603383	SELENOK	selenoprotein K	The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER st ... (more) ress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Pseudogenes of this locus have been identified on chromosomes 6 and 19.[provided by RefSeq, Aug 2017]	3	53884417	53891859	Human	117	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1623089	Selenok	selenoprotein K	The protein encoded by this gene belongs to the selenoprotein K family. It is a transmembrane protein that is localized in the endoplasmic reticulum (ER), and is involved in ER-associated degradation (ERAD) of misfolded, glycosylated proteins. It also has a role in the protection of cells from ER st ... (more) ress-induced apoptosis. Knockout studies in mice show the importance of this gene in promoting Ca(2+) flux in immune cells and mounting effective immune response. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Multiple pseudogenes of this locus have been identified. [provided by RefSeq, Sep 2017]	14	29690337	29697031	Mouse	139	old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
12283973	SELENOK	selenoprotein K	INVOLVED IN calcium ion transport (ortholog); macrophage derived foam cell differentiation (ortholog); positive regulation of cell migration (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)	20	36109095	36115792	Dog	27	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
18362999	SELENOK	selenoprotein K	INVOLVED IN calcium ion transport (ortholog); intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ortholog); macrophage derived foam cell differentiation (ortholog); FOUND IN endoplasmic reticulum (ortholog)				Green Monkey	26	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
18906167	Selenok	selenoprotein K	INVOLVED IN calcium ion transport (ortholog); intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (ortholog); macrophage derived foam cell differentiation (ortholog); FOUND IN endoplasmic reticulum (ortholog)				Naked Mole-Rat	26	old_gene_symbol	gene, protein-coding, MODEL [RefSeq]
14076420	SELENOK	selenoprotein K	INVOLVED IN calcium ion transport (ortholog); macrophage derived foam cell differentiation (ortholog); positive regulation of cell migration (ortholog); FOUND IN endoplasmic reticulum (ortholog); endoplasmic reticulum membrane (ortholog)				Pig	32	old_gene_symbol	gene, protein-coding, VALIDATED [RefSeq]
16556172	AC093716.1	pseudogene similar to part of selenoprotein K SELK					Human		name	gene, processed_pseudogene