| 1308336 | Rps6ka5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (ortholog); histone H2AS1 kinase activity (ortholog); histone H3S10 kinase activity (ortholog); INVOLVED IN interleukin-1-mediated signaling pathway (ortholog); intracellular signal transduction (ortholog); negative regulation of DNA-templated transcriptio n (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; mitogen activated protein kinase signaling pathway; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; aristolochic acid A | 6 | 125558434 | 125736576 | Rat | 200 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1318046 | RPS6KA5 | ribosomal protein S6 kinase A5 | Enables ATP binding activity and protein kinase activity. Involved in several processes, including interleukin-1-mediated signaling pathway; protein modification process; and regulation of DNA-templated transcription. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, A pr 2025] | 14 | 90847861 | 91060641 | Human | 194 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 1318047 | Rps6ka5 | ribosomal protein S6 kinase, polypeptide 5 | Enables ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including protein phosphorylation; regulation of DNA-templated transcription; and regulation of postsynapse organization. Located in nucleus. Orthologous to human RPS6KA5 RPS6KA5 (ribosomal protein S6 kinase A5). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 100514692 | 100691693 | Mouse | 225 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8940843 | Rps6ka5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (ortholog); histone H2AS1 kinase activity (ortholog); histone H3S10 kinase activity (ortholog); INVOLVED IN interleukin-1-mediated signaling pathway (ortholog); intracellular signal transduction (ortholog); negative regulation of DNA-templated transcriptio n (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; ASSOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955438 | 13218451 | 13392080 | Chinchilla | 37 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11891814 | RPS6KA5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (inferred); histone H2AS1 kinase activity (inferred); histone H3S10 kinase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; AS SOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 14 | 71489654 | 71679250 | Bonobo | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12358994 | RPS6KA5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (inferred); histone H2AS1 kinase activity (inferred); histone H3S10 kinase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; AS SOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | 8 | 61801185 | 61962846 | Dog | 54 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12457760 | Rps6ka5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (inferred); histone H2AS1 kinase activity (inferred); histone H3S10 kinase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; AS SOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936488 | 17937421 | 18132845 | Squirrel | 50 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13847685 | RPS6KA5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (inferred); histone H2AS1 kinase activity (inferred); histone H3S10 kinase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; AS SOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Pig | 55 | symbol , old_gene_name | gene, protein-coding, MODEL [RefSeq] |
| 18617753 | RPS6KA5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (inferred); histone H2AS1 kinase activity (inferred); histone H3S10 kinase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; AS SOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 53 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18913588 | Rps6ka5 | ribosomal protein S6 kinase A5 | ENCODES a protein that exhibits ATP binding (inferred); histone H2AS1 kinase activity (inferred); histone H3S10 kinase activity (inferred); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN p38 MAPK signaling pathway; the extracellular signal-regulated Raf/Mek/Erk signaling pathway; AS SOCIATED WITH Cocaine-Related Disorders (ortholog); COVID-19 (ortholog); FOUND IN cytoplasm (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 50 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285776410 | rps6ka5 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 286411174 | rps6ka5.L | | | | | | African Clawed Frog | | symbol | gene, null |