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15 records found for search term Rdh8
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1319361RDH8retinol dehydrogenase 8This gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [191001348310022279Human36symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1589829Rdh8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cycle metabolic pathway; retinol metabolic pathway; vitamin A deficiency pathway; FOUND IN cytoplasm (i82762938027636651Rat35symbol , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1615671Rdh8retinol dehydrogenase 8Enables all-trans-retinol dehydrogenase (NAD+) activity. Acts upstream of or within retinol metabolic process and visual perception. Predicted to be active in cytosol. Is expressed in eye. Used to study age related macular degeneration 2. Orthologous to human RDH892072979020739354Mouse50symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8754591Rdh8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cycle metabolic pathway; retinol metabolic pathway; vitamin A deficiency pathwayNW_00495549513883851393209Chinchilla6symbolgene, protein-coding, MODEL [RefSeq]
11821571RDH8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); all-trans-retinol dehydrogenase (NADP+) activity (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PART1995659189575017Bonobo20symbolgene, protein-coding, MODEL [RefSeq]
12225329RDH8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); all-trans-retinol dehydrogenase (NADP+) activity (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PART205102963351035910Dog19symbolgene, protein-coding, MODEL [RefSeq]
12582225Rdh8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); oxidoreductase activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cyclNW_004936659439541445645Squirrel19symbolgene, protein-coding, MODEL [RefSeq]
155233616rdh8Tropical Clawed Frogsymbolgene, null
626037122Rdh8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (ortholog); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cycle metabolic pathway; retinol metabolic pathway; vitamin A deficiency pathwayBlack Rat6symbolgene, protein-coding, MODEL [RefSeq]
14118742RDH8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); all-trans-retinol dehydrogenase (NADP+) activity (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTPig20symbolgene, protein-coding, MODEL [RefSeq]
18771606RDH8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); oxidoreductase activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cycle metabolic pathway; retinol metabolic pathway; vitamin A deficGreen Monkey10symbolgene, protein-coding, MODEL [RefSeq]
18906062Rdh8retinol dehydrogenase 8ENCODES a protein that exhibits all-trans-retinol dehydrogenase (NAD+) activity (inferred); estradiol 17-beta-dehydrogenase [NAD(P)+] activity (inferred); oxidoreductase activity (inferred); INVOLVED IN retinol metabolic process (ortholog); visual perception (ortholog); PARTICIPATES IN retinoid cyclNaked Mole-Rat19symbolgene, protein-coding, MODEL [RefSeq]
155234453rdh8.LAfrican Clawed Frogsymbolgene, null
155255648rdh8.SAfrican Clawed Frogsymbolgene, null
1553161Hsd17b6hydroxysteroid (17-beta) dehydrogenase 6Enables steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Predicted to be involved in brexanolone catabolic process and retinol metabolic process. Predicted to be located in early endosome membrane and endoplasmic reticulum. Predicted to be active in intra10127826800127843517Mouse196old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]