| 1306867 | Rab23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); GTPase activity (ortholog); INVOLVED IN autophagosome assembly (ortholog); cellular defense response (ortholog); cilium assembly (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol; 4,4'-sulfonyldiphenol | 9 | 43440047 | 43463327 | Rat | 160 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 1315728 | RAB23 | RAB23, member RAS oncogene family | This gene encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervou s system development by antagonizing sonic hedgehog signaling. Disruption of this gene has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | 6 | 57186992 | 57222307 | Human | 317 | symbol , COSMIC , name , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1315729 | Rab23 | RAB23, member RAS oncogene family | Predicted to enable GTPase activity. Involved in dorsal/ventral neural tube patterning and neural tube closure. Acts upstream of or within several processes, including embryonic digit morphogenesis; regulation of smoothened signaling pathway; and spinal cord dorsal/ventral patterning. Located in end osome membrane and plasma membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in Carpenter syndrome 1. Orthologous to human RAB23 (RAB23, member RAS oncogene family). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 33758991 | 33781642 | Mouse | 226 | symbol , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 9041456 | Rab23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); GTPase activity (ortholog); INVOLVED IN autophagosome assembly (ortholog); cellular defense response (ortholog); cilium assembly (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | NW_004955502 | 2947170 | 2980634 | Chinchilla | 38 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 11771406 | RAB23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN dorsal/ventral neural tube patterning (ortholog); embryonic digit morphogenesis (ortholog); negative regulation of proteolysis (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | 6 | 56744948 | 56780187 | Bonobo | 53 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12094810 | RAB23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN cellular defense response (ortholog); cilium assembly (ortholog); craniofacial suture morphogenesis (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH b ladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); phagocytic vesicle (ortholog) | 12 | 24388530 | 24438956 | Dog | 54 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 12617854 | Rab23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN dorsal/ventral neural tube patterning (ortholog); embryonic digit morphogenesis (ortholog); negative regulation of proteolysis (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | NW_004936476 | 4095829 | 4127714 | Squirrel | 53 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14388355 | Rab23 | | | | | | Fly | | symbol | gene, null |
| 18909813 | Rab23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN dorsal/ventral neural tube patterning (ortholog); embryonic digit morphogenesis (ortholog); negative regulation of proteolysis (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | | | | Naked Mole-Rat | 53 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 14278243 | RAB23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN dorsal/ventral neural tube patterning (ortholog); embryonic digit morphogenesis (ortholog); negative regulation of proteolysis (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | | | | Pig | 59 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155244994 | rab23 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18445611 | RAB23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN dorsal/ventral neural tube patterning (ortholog); embryonic digit morphogenesis (ortholog); negative regulation of proteolysis (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (inferred); cytoplasm (inferred); cytoplasmic vesicle (inferred) | | | | Green Monkey | 53 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 626156207 | Rab23 | RAB23, member RAS oncogene family | ENCODES a protein that exhibits G protein activity (ortholog); GTPase activity (ortholog); INVOLVED IN autophagosome assembly (ortholog); cellular defense response (ortholog); cilium assembly (ortholog); PARTICIPATES IN Hedgehog signaling pathway; ASSOCIATED WITH bladder exstrophy-epispadias-cloacal exstrophy complex (ortholog); Carpenter syndrome (ortholog); Carpenter syndrome 1 (ortholog); FOUND IN autophagosome (ortholog); cytoplasm (ortholog); cytosol (ortholog) | | | | Black Rat | 38 | symbol , name | gene, protein-coding, MODEL [RefSeq] |
| 155237320 | rab23.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 1606246 | TCTN1 | tectonic family member 1 | This gene encodes a member of a family of secreted and transmembrane proteins. The orthologous gene in mouse functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. This protein is a component of the tectonic-like complex, which fo rms a barrier between the ciliary axoneme and the basal body. A mutation in this gene was found in a family with Joubert syndrome-13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] | 12 | 110614129 | 110649430 | Human | 228 | description | gene, protein-coding, REVIEWED [RefSeq] |