| 708516 | Ptpn7 | protein tyrosine phosphatase, non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN protein dephosphorylation (ortholog); PARTICIPATES IN mitogen activated protein kinase signaling pathway; FOUND IN cytoplasm (o rtholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog); INTERACTS WITH 1,3-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol | 13 | 49122679 | 49136096 | Rat | 88 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1550868 | Ptpn7 | protein tyrosine phosphatase, non-receptor type 7 | Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within protein dephosphorylation. Predicted to be located in cytoplasmic side of plasma membrane; cytosol; and mitotic spindle. Is expressed in liver and thymus primordium. Orthologous to human PTPN7 0;'>PTPN7 (protein tyrosine phosphatase non-receptor type 7). [provided by Alliance of Genome Resources, Jul 2025] | 1 | 135059577 | 135073064 | Mouse | 98 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1605720 | PTPN7 | protein tyrosine phosphatase non-receptor type 7 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expre ssed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010] | 1 | 202147013 | 202161588 | Human | 95 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8880799 | Ptpn7 | protein tyrosine phosphatase non-receptor type 7 | INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog) | NW_004955406 | 38233409 | 38249940 | Chinchilla | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11869515 | PTPN7 | protein tyrosine phosphatase non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein kinase binding (inferred); INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog) | 1 | 177744963 | 177759611 | Bonobo | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12346997 | PTPN7 | protein tyrosine phosphatase non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (i nferred) | 7 | 859124 | 869168 | Dog | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12543896 | Ptpn7 | protein tyrosine phosphatase non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein kinase binding (inferred); INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cell junction (inferred); cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred) | NW_004936567 | 2381519 | 2392562 | Squirrel | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14077260 | PTPN7 | protein tyrosine phosphatase non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein tyrosine phosphatase activity (inferred); INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred); cytosol (i nferred) | | | | Pig | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626052975 | Ptpn7 | protein tyrosine phosphatase non-receptor type 7 | INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog) | | | | Black Rat | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18700401 | PTPN7 | protein tyrosine phosphatase non-receptor type 7 | INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog); cytosol (ortholog) | | | | Green Monkey | 9 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18923056 | Ptpn7 | protein tyrosine phosphatase non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein kinase binding (inferred); INVOLVED IN protein dephosphorylation (ortholog); FOUND IN cytoplasm (ortholog); cytoplasmic side of plasma membrane (ortholog) | | | | Naked Mole-Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 20867047 | PTPN7 | protein tyrosine phosphatase non-receptor type 7 | ENCODES a protein that exhibits hydrolase activity (inferred); phosphoprotein phosphatase activity (inferred); protein kinase binding (inferred); INVOLVED IN signal transduction (inferred); FOUND IN cell junction (inferred); cytoplasm (inferred); cytoplasmic side of plasma membrane (inferred) | | | | Green Monkey | 13 | symbol | gene, protein-coding |
