| 3436 | Ptgfr | prostaglandin F receptor | ENCODES a protein that exhibits prostaglandin F receptor activity (ortholog); INVOLVED IN cellular response to prostaglandin D stimulus (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of cell population proliferation (ortholog); PARTICIPATES IN calcium/calcium-me diated signaling pathway; ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (ortholog); myoepithelioma (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 2 | 243390820 | 243426647 | Rat | 154 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 734294 | Ptgfr | prostaglandin F receptor | Predicted to enable prostaglandin F receptor activity. Involved in positive regulation of gene expression and response to estradiol. Acts upstream of or within negative regulation of apoptotic process and response to lipopolysaccharide. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. Is expressed in cloaca; genital tubercle; jaw; and viscerocranium. Orthologous to human PTGFR (prostaglandin F receptor). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 151504247 | 151543165 | Mouse | 154 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 737369 | PTGFR | prostaglandin F receptor | The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus . Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 1 | 78490974 | 78540701 | Human | 148 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8841448 | Ptgfr | prostaglandin F receptor | ENCODES a protein that exhibits prostaglandin F receptor activity (ortholog); INVOLVED IN cellular response to prostaglandin D stimulus (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (ortholog); myoepithelioma (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); plasma membrane (ortholog) | NW_004955423 | 14768208 | 14816462 | Chinchilla | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11746711 | PTGFR | prostaglandin F receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); prostaglandin F receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (orth olog); myoepithelioma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); membrane (inferred) | 1 | 77714164 | 77762171 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12352857 | PTGFR | prostaglandin F receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); prostaglandin F receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (orth olog); myoepithelioma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); membrane (inferred) | 6 | 68460107 | 68498793 | Dog | 27 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 12690044 | Ptgfr | prostaglandin F receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); prostaglandin F receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (orth olog); myoepithelioma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); membrane (inferred) | NW_004936571 | 5235678 | 5274417 | Squirrel | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13887268 | PTGFR | prostaglandin F receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); prostaglandin F receptor activity (inferred); prostaglandin receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (ortholog); myoepithelioma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); membrane (inferred) | | | | Pig | 28 | symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 18410190 | PTGFR | prostaglandin F receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); prostaglandin F receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (orth olog); myoepithelioma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); membrane (inferred) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155240723 | ptgfr | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 625900280 | Ptgfr | prostaglandin F receptor | ENCODES a protein that exhibits prostaglandin F receptor activity (ortholog); INVOLVED IN cellular response to prostaglandin D stimulus (ortholog); negative regulation of apoptotic process (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (ortholog); myoepithelioma (ortholog); FOUND IN cytoplasm (ortholog); extracellular region (ortholog); plasma membrane (ortholog) | | | | Black Rat | 13 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18923631 | Ptgfr | prostaglandin F receptor | ENCODES a protein that exhibits G protein-coupled receptor activity (inferred); prostaglandin F receptor activity (inferred); INVOLVED IN negative regulation of apoptotic process (ortholog); response to lipopolysaccharide (ortholog); ASSOCIATED WITH Airway Obstruction (ortholog); endometriosis (orth olog); myoepithelioma (ortholog); FOUND IN cytoplasm (inferred); extracellular region (inferred); membrane (inferred) | | | | Naked Mole-Rat | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155257095 | ptgfr.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155257563 | ptgfr.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 3437 | Ptgfrn | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); myoblast fusion involved in skeletal muscle regeneration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodib enzodioxine; 2,4-dinitrotoluene | 2 | 191158166 | 191233432 | Rat | 116 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 733934 | PTGFRN | prostaglandin F2 receptor inhibitor | Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration. Predicted to act upstream of or within lipid droplet organization. Located in cell surface. [provided by Alliance of Genome Resources, Jul 2025] | 1 | 116909916 | 116990353 | Human | 113 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, VALIDATED [RefSeq] |
| 736879 | Ptgfrn | prostaglandin F2 receptor negative regulator | Involved in myoblast fusion involved in skeletal muscle regeneration. Acts upstream of or within lipid droplet organization. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Predicted to be active in membrane. Is expressed in several structures, including central nervou s system; glans of male genital tubercle; palatal shelf; skeleton; and submandibular gland primordium. Orthologous to human PTGFRN (prostaglandin F2 receptor inhibitor). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 100947546 | 101018061 | Mouse | 113 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8917357 | Ptgfrn | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); myoblast fusion involved in skeletal muscle regeneration (ortholog); ASSOCIATED WITH COVID-19 (ortholog) | NW_004955435 | 20046712 | 20092051 | Chinchilla | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11916059 | PTGFRN | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred); membrane (inferred) | 1 | 85530198 | 85610720 | Bonobo | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12181206 | PTGFRN | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred) | 17 | 54337778 | 54378363 | Dog | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12644382 | Ptgfrn | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred); membrane (inferred) | NW_004936627 | 2069066 | 2108526 | Squirrel | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155248965 | ptgfrn | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 626056508 | Ptgfrn | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); myoblast fusion involved in skeletal muscle regeneration (ortholog); ASSOCIATED WITH COVID-19 (ortholog) | | | | Black Rat | 7 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18375400 | PTGFRN | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Green Monkey | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14225033 | PTGFRN | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 11 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18919485 | Ptgfrn | prostaglandin F2 receptor inhibitor | INVOLVED IN lipid droplet organization (ortholog); myoblast fusion involved in skeletal muscle regeneration (ortholog); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN endoplasmic reticulum membrane (inferred); Golgi apparatus (inferred); membrane (inferred) | | | | Naked Mole-Rat | 10 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155255826 | ptgfrn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155258976 | ptgfrn.S | | | | | | African Clawed Frog | | symbol | gene, null |