| 620280 | Prok2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding; INVOLVED IN angiogenesis (ortholog); chemotaxis (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog); FOUND IN extracellular region (in ferred); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3-dinitrobenzene; 1-naphthyl isothiocyanate | 4 | 133903210 | 133918126 | Rat | 117 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1350776 | PROK2 | prokineticin 2 | This gene encodes a protein expressed in the suprachiasmatic nucleus (SCN) circadian clock that may function as the output component of the circadian clock. The secreted form of the encoded protein may also serve as a chemoattractant for neuronal precursor cells in the olfactory bulb. Proteins from other vertebrates which are similar to this gene product were isolated based on homology to snake venom and secretions from frog skin, and have been shown to have diverse functions. Mutations in this gene are associated with Kallmann syndrome 4. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 3 | 71771655 | 71785148 | Human | 219 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1552878 | Prok2 | prokineticin 2 | Predicted to enable G protein-coupled receptor binding activity. Acts upstream of or within circadian rhythm. Predicted to be located in extracellular region. Is expressed in several structures, including genitourinary system; heart; liver; lung; and telencephalon. Human ortholog(s) of this gene imp licated in hypogonadotropic hypogonadism 4 with or without anosmia. Orthologous to human PROK2 (prokineticin 2). [provided by Alliance of Genome Resources, Jul 2025] | 6 | 99687833 | 99703368 | Mouse | 138 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 8881740 | Prok2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); chemotaxis (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog) | NW_004955421 | 16325519 | 16339458 | Chinchilla | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12047745 | PROK2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred) | 3 | 71711334 | 71724865 | Bonobo | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12489311 | Prok2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred) | NW_004936603 | 3299736 | 3419539 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 19261776 | PROK2 | prokineticin 2 | FOUND IN extracellular region (inferred) | | | | Dog | 1 | symbol | gene, protein-coding |
| 18900670 | Prok2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred) | | | | Naked Mole-Rat | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18586392 | PROK2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); chemotaxis (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog) | | | | Green Monkey | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625882698 | Prok2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN angiogenesis (ortholog); chemotaxis (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog) | | | | Black Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285889661 | prok2 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14181607 | PROK2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred) | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 40907200 | PROK2 | prokineticin 2 | ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); INVOLVED IN circadian rhythm (ortholog); ASSOCIATED WITH amenorrhea (ortholog); disorder of sexual development (ortholog); genetic disease (ortholog); FOUND IN extracellular region (inferred) | | | | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288068033 | prok2.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 286520267 | prok2.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 38632403 | PROK2-DT | PROK2 divergent transcript | | 3 | 71785390 | 71786427 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16562606 | PROK2-DT | PROK2 divergent transcript | | | | | Human | | symbol , COSMIC , name , Human Proteome Map | gene, lncrna |
| 2303672 | ZNF841 | zinc finger protein 841 | Predicted to enable DNA binding activity and zinc ion binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025] | 19 | 52058490 | 52095765 | Human | 30 | old_gene_name , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |