| 1304651 | Ppp1r13b | protein phosphatase 1, regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN positive regulation of cellular process; intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN perinuclear region of cytoplasm; cytosol (ortholog); nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; all-trans-retinoic acid | 6 | 136711834 | 136785068 | Rat | 89 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1312214 | PPP1R13B | protein phosphatase 1 regulatory subunit 13B | This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. Th ey promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008] | 14 | 103733195 | 103848814 | Human | 102 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1312215 | Ppp1r13b | protein phosphatase 1, regulatory subunit 13B | Predicted to enable p53 binding activity. Predicted to be involved in intrinsic apoptotic signaling pathway by p53 class mediator. Predicted to be located in several cellular components, including cytosol; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be active in nucleus. Is expres sed in several structures, including blood; brain; cardiovascular system; embryo mesenchyme; and yolk sac. Orthologous to human PPP1R13B (protein phosphatase 1 regulatory subunit 13B). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 111794892 | 111874549 | Mouse | 111 | symbol , PhenoGen , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 9054371 | Ppp1r13b | protein phosphatase 1 regulatory subunit 13B | INVOLVED IN intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | NW_004955538 | 2519765 | 2594769 | Chinchilla | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11897077 | PPP1R13B | protein phosphatase 1 regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | 14 | 84359917 | 84474892 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12409924 | PPP1R13B | protein phosphatase 1 regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | 8 | 71462338 | 71518918 | Dog | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12462712 | Ppp1r13b | protein phosphatase 1 regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | NW_004936621 | 1383137 | 1447376 | Squirrel | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626155619 | Ppp1r13b | protein phosphatase 1 regulatory subunit 13B | INVOLVED IN intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); nucleus (ortholog) | | | | Black Rat | 17 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18627746 | PPP1R13B | protein phosphatase 1 regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Green Monkey | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252020 | ppp1r13b | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14097524 | PPP1R13B | protein phosphatase 1 regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN perinuclear region of cytoplasm (ortholog) | | | | Pig | 26 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18935513 | Ppp1r13b | protein phosphatase 1 regulatory subunit 13B | ENCODES a protein that exhibits p53 binding (inferred); INVOLVED IN intrinsic apoptotic signaling pathway by p53 class mediator (ortholog); positive regulation of cellular process (ortholog); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH Childhood Schizophrenia (ortholog); FOUND IN cytosol (ortholog); nucleoplasm (ortholog); perinuclear region of cytoplasm (ortholog) | | | | Naked Mole-Rat | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252019 | ppp1r13b.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 626172005 | ppp1r13b.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 626181866 | ppp1r13b.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 6892745 | PPP1R13B-DT | PPP1R13B divergent transcript | INTERACTS WITH 4,4'-sulfonyldiphenol; bisphenol F; fulvestrant | 14 | 103847721 | 103858049 | Human | 3 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 1347285 | PPP1R13L | protein phosphatase 1 regulatory subunit 13 like | IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.[supplied by OMIM, Mar 2008] | 19 | 45379638 | 45406361 | Human | 188 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |
| 1617213 | Ppp1r13l | protein phosphatase 1, regulatory subunit 13 like | Predicted to enable identical protein binding activity. Involved in negative regulation of inflammatory response. Acts upstream of or within several processes, including cardiac muscle contraction; heart development; and negative regulation of transcription by RNA polymerase II. Predicted to be loca ted in cell junction; cytosol; and intercellular bridge. Is expressed in esophagus; sensory organ; submandibular gland primordium; and vibrissa. Used to study arrhythmogenic right ventricular cardiomyopathy. Orthologous to human PPP1R13L (protein phosphatase 1 regulatory subunit 13 like). [provided by Alliance of Genome Resources, Apr 2025] | 7 | 19093639 | 19112465 | Mouse | 202 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |