| 1310595 | Pla2g4e | phospholipase A2, group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (ortholog); N-acyltransferase activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN N-acylphosphatidylethanolamine metabolic process (ortholog); positive regulation of endocytic recycling (o rtholog); PARTICIPATES IN alpha-linolenic acid metabolic pathway; arachidonic acid metabolic pathway; ether lipid metabolic pathway; FOUND IN cytoplasm (ortholog); early endosome membrane (ortholog); lysosomal membrane (ortholog); INTERACTS WITH acrylamide; bisphenol A; cadmium dichloride | 3 | 127586318 | 127652369 | Rat | 91 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1321594 | Pla2g4e | phospholipase A2, group IVE | Enables several functions, including phosphatidylinositol phosphate binding activity; phosphatidylinositol-3,4-bisphosphate binding activity; and phospholipase A2 activity. Involved in N-acylphosphatidylethanolamine metabolic process and positive regulation of endocytic recycling. Located in early e ndosome membrane; lysosomal membrane; and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human PLA2G4E (phospholipase A2 group IVE). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 119996893 | 120075816 | Mouse | 84 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1606471 | PLA2G4E | phospholipase A2 group IVE | This gene encodes a member of the cytosolic phospholipase A2 group IV family. Members of this family are involved in regulation of membrane tubule-mediated transport. The enzyme encoded by this member of the family plays a role in trafficking through the clathrin-independent endocytic pathway. The e nzyme regulates the recycling process via formation of tubules that transport internalized clathrin-independent cargo proteins back to the cell surface. [provided by RefSeq, Jan 2017] | 15 | 41981582 | 42050703 | Human | 93 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8984025 | Pla2g4e | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (ortholog); N-acyltransferase activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN N-acylphosphatidylethanolamine metabolic process (ortholog); positive regulation of endocytic recycling (o rtholog); FOUND IN cytoplasm (ortholog); early endosome membrane (ortholog); lysosomal membrane (ortholog) | NW_004955416 | 8765620 | 8826184 | Chinchilla | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11913579 | PLA2G4E | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (inferred); calcium ion binding (inferred); calcium-dependent phospholipid binding (inferred); INVOLVED IN glycerophospholipid catabolic process (inferred); glycerophospholipid metabolic process (inferred); lipid catabolic process (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred) | 15 | 20937573 | 20975388 | Bonobo | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12361293 | PLA2G4E | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (inferred); calcium ion binding (inferred); carboxylic ester hydrolase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); glycerol metabolic process (inferred); leukotriene biosynthetic process (inferred) ; FOUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred) | 30 | 9018238 | 9077258 | Dog | 40 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12589387 | Pla2g4e | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (inferred); calcium ion binding (inferred); calcium-dependent phospholipid binding (inferred); INVOLVED IN glycerophospholipid catabolic process (inferred); lipid catabolic process (inferred); lipid metabolic process (inferred); F OUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred) | NW_004936471 | 5300932 | 5370150 | Squirrel | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 626085751 | Pla2g4e | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (ortholog); N-acyltransferase activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); INVOLVED IN N-acylphosphatidylethanolamine metabolic process (ortholog); positive regulation of endocytic recycling (o rtholog); FOUND IN cytoplasm (ortholog); early endosome membrane (ortholog); lysosomal membrane (ortholog) | | | | Black Rat | 18 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13954110 | PLA2G4E | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (inferred); calcium ion binding (inferred); carboxylic ester hydrolase activity (inferred); INVOLVED IN fatty acid biosynthetic process (inferred); glycerol metabolic process (inferred); leukotriene biosynthetic process (inferred) ; FOUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 43 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18505090 | PLA2G4E | phospholipase A2 group IVE | ENCODES a protein that exhibits A2-type glycerophospholipase activity (inferred); calcium ion binding (inferred); calcium-dependent phospholipid binding (inferred); INVOLVED IN glycerophospholipid catabolic process (inferred); glycerophospholipid metabolic process (inferred); lipid catabolic process (inferred); FOUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred) | | | | Green Monkey | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18925956 | Pla2g4e | phospholipase A2 group IVE | ENCODES a protein that exhibits N-acyltransferase activity (ortholog); phosphatidylinositol-3,4,5-trisphosphate binding (ortholog); phosphatidylinositol-3,4-bisphosphate binding (ortholog); INVOLVED IN N-acylphosphatidylethanolamine metabolic process (ortholog); positive regulation of endocytic recy cling (ortholog); FOUND IN cytoplasm (ortholog); early endosome membrane (ortholog); lysosomal membrane (ortholog) | | | | Naked Mole-Rat | 36 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 9681189 | PLA2G4E-AS1 | PLA2G4E antisense RNA 1 | INTERACTS WITH dimethylselenide; hydroxyl; ozone | 15 | 41972763 | 41999094 | Human | 3 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 16561430 | AC039056.1 | novel transcript, antisense to PLA2G4E | | | | | Human | | name | gene, lncrna |