PLA2G4E (phospholipase A2 group IVE) - Rat Genome Database

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Gene: PLA2G4E (phospholipase A2 group IVE) Chlorocebus sabaeus
Analyze
Symbol: PLA2G4E
Name: phospholipase A2 group IVE
RGD ID: 18505090
Description: ENCODES a protein that exhibits calcium ion binding (inferred); calcium-dependent phospholipase A2 activity (inferred); calcium-dependent phospholipid binding (inferred); INVOLVED IN glycerophospholipid catabolic process (inferred); glycerophospholipid metabolic process (inferred); lipid catabolic process (inferred); ASSOCIATED WITH Bloom syndrome (ortholog); colorectal cancer (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); early endosome membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: cytosolic phospholipase A2 epsilon
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12640,938,730 - 41,001,787 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2640,939,712 - 41,001,217 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048100,001,209 - 100,063,250 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
PLA2G4E
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12640,938,730 - 41,001,787 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2640,939,712 - 41,001,217 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666048100,001,209 - 100,063,250 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
PLA2G4E
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381541,981,582 - 42,050,703 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1541,981,394 - 42,051,190 (-)EnsemblGRCh38hg38GRCh38
GRCh371542,273,780 - 42,342,901 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361540,063,244 - 40,089,737 (-)NCBINCBI36Build 36hg18NCBI36
Celera1519,043,598 - 19,070,102 (-)NCBICelera
Cytogenetic Map15q15.1NCBI
HuRef1519,121,756 - 19,190,910 (-)NCBIHuRef
CHM1_11542,392,249 - 42,461,343 (-)NCBICHM1_1
T2T-CHM13v2.01539,787,553 - 39,856,691 (-)NCBIT2T-CHM13v2.0
Pla2g4e
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392119,996,893 - 120,075,816 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2119,996,893 - 120,075,816 (-)EnsemblGRCm39 Ensembl
GRCm382120,166,412 - 120,245,630 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2120,166,412 - 120,245,335 (-)EnsemblGRCm38mm10GRCm38
MGSCv372119,992,148 - 120,071,071 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362119,857,853 - 119,936,776 (-)NCBIMGSCv36mm8
Celera2121,326,986 - 121,399,932 (-)NCBICelera
Cytogenetic Map2E5NCBI
cM Map260.24NCBI
Pla2g4e
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83127,586,318 - 127,652,369 (-)NCBIGRCr8
mRatBN7.23107,132,540 - 107,198,609 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3107,132,541 - 107,198,233 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.03111,952,396 - 112,018,470 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3111,952,348 - 111,994,337 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03118,500,163 - 118,566,233 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43106,670,159 - 106,735,089 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13106,567,403 - 106,631,517 (-)NCBI
Celera3106,041,283 - 106,107,262 (-)NCBICelera
Cytogenetic Map3q35NCBI
Pla2g4e
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554168,765,561 - 8,804,616 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554168,765,620 - 8,826,184 (-)NCBIChiLan1.0ChiLan1.0
PLA2G4E
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21631,227,604 - 31,264,889 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11535,376,429 - 35,416,124 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01520,937,573 - 20,975,388 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11539,095,777 - 39,165,161 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1539,095,777 - 39,165,161 (-)Ensemblpanpan1.1panPan2
PLA2G4E
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1309,018,238 - 9,077,258 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl309,020,079 - 9,075,999 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha309,076,973 - 9,135,690 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0309,153,388 - 9,212,395 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl309,155,138 - 9,212,408 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1309,074,123 - 9,132,817 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0309,178,334 - 9,237,062 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0309,313,127 - 9,372,095 (-)NCBIUU_Cfam_GSD_1.0
Pla2g4e
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864087,452,829 - 87,488,718 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364715,302,688 - 5,370,182 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364715,300,932 - 5,370,150 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PLA2G4E
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1129,289,732 - 129,364,021 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11129,288,727 - 129,364,034 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21144,339,794 - 144,349,251 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pla2g4e
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248049,140,353 - 9,227,102 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248049,142,525 - 9,227,049 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
25 25 17 22 22 20 20

Sequence


Ensembl Acc Id: ENSCSAT00000006242   ⟹   ENSCSAP00000004452
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl2640,939,712 - 41,001,217 (+)Ensembl
RefSeq Acc Id: XM_008016926   ⟹   XP_008015117
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.12640,938,730 - 41,001,787 (+)NCBI
Vero_WHO_p1.0NW_023666048100,001,209 - 100,063,250 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008015117 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000004452.1
RefSeq Acc Id: XP_008015117   ⟸   XM_008016926
- UniProtKB: A0A0D9R763 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000004452   ⟸   ENSCSAT00000006242


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000008242 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000006242.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
  Cytosolic phospholipase A2 catalytic domain UniProtKB/TrEMBL
InterPro Acyl_Trfase/lysoPLipase UniProtKB/TrEMBL
  C2_cPLA2 UniProtKB/TrEMBL
  C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  cPLA2_C2 UniProtKB/TrEMBL
  LysoPLipase_cat_dom UniProtKB/TrEMBL
NCBI Gene PLA2G4E ENTREZGENE
PANTHER CYTOSOLIC PHOSPHOLIPASE A2 UniProtKB/TrEMBL
  CYTOSOLIC PHOSPHOLIPASE A2 EPSILON UniProtKB/TrEMBL
Pfam cPLA2_C2 UniProtKB/TrEMBL
  PF00168 UniProtKB/TrEMBL
  PLA2_B UniProtKB/TrEMBL
PROSITE PLA2C UniProtKB/TrEMBL
  PS50004 UniProtKB/TrEMBL
SMART PLAc UniProtKB/TrEMBL
  SM00239 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  SSF52151 UniProtKB/TrEMBL
UniProt A0A0D9R763 ENTREZGENE, UniProtKB/TrEMBL