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18 records found for search term Pawr
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
69065Pawrpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding; protein kinase C binding; protein phosphatase 1 binding; INVOLVED IN actin filament bundle assembly; apoptotic process; calcium ion import across plasma membrane; PARTICIPATES IN ceramide signaling pathway; ASSOCIATED WITH Acute Lung Injury; Brain Injur74553148045611492Rat223symbol , old_gene_name , PhenoGengene, protein-coding, VALIDATED [RefSeq]
69120PAWRpro-apoptotic WT1 regulatorThis gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mecha127958487979690964Human229symbol , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
737403PawrPRKC, apoptosis, WT1, regulatorPredicted to enable actin binding activity; enzyme binding activity; and leucine zipper domain binding activity. Involved in several processes, including positive regulation of cellular senescence; positive regulation of hydrogen peroxide-mediated programmed cell death; and regulation of gene expres10108168050108250708Mouse259symbol , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8774795Pawrpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); enzyme binding (ortholog); leucine zipper domain binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic process (ortholog); apoptotic signaling pathway (ortholog); PARTICIPATES IN ceramide signaling pathway; ASSONW_0049554051843471118540710Chinchilla81symbolgene, protein-coding, MODEL [RefSeq]
11951393PAWRpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); protein kinase C binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic signaling pathway (ortholog); calcium ion import across plasma membrane (ortholog); PARTICIPATES I127711428277224116Bonobo81symbolgene, protein-coding, MODEL [RefSeq]
12362063PAWRpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); protein kinase C binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic signaling pathway (ortholog); calcium ion import across plasma membrane (ortholog); PARTICIPATES I152211401422159287Dog83symbolgene, protein-coding, MODEL [RefSeq]
12679685Pawrpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); protein kinase C binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic signaling pathway (ortholog); calcium ion import across plasma membrane (ortholog); PARTICIPATES INW_004936698650225746593Squirrel81symbolgene, protein-coding, MODEL [RefSeq]
14088945PAWRpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); protein kinase C binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic signaling pathway (ortholog); calcium ion import across plasma membrane (ortholog); PARTICIPATES IPig83symbolgene, protein-coding, MODEL [RefSeq]
18605375PAWRpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); protein kinase C binding (ortholog); protein phosphatase 1 binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic signaling pathway (ortholog); calcium ion import across plasma membrane (ortholog); PARTICIPATES IGreen Monkey81symbolgene, protein-coding, MODEL [RefSeq]
18922642Pawrpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); enzyme binding (ortholog); leucine zipper domain binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic signaling pathway (ortholog); calcium ion import across plasma membrane (ortholog); PARTICIPATES IN ceramideNaked Mole-Rat81symbolgene, protein-coding, MODEL [RefSeq]
626000979Pawrpro-apoptotic WT1 regulatorENCODES a protein that exhibits actin binding (ortholog); enzyme binding (ortholog); leucine zipper domain binding (ortholog); INVOLVED IN actin filament bundle assembly (ortholog); apoptotic process (ortholog); apoptotic signaling pathway (ortholog); PARTICIPATES IN ceramide signaling pathway; ASSOBlack Rat81symbolgene, protein-coding, MODEL [RefSeq]
155243662pawrTropical Clawed Frogsymbolgene, null
155253892pawr.LAfrican Clawed Frogsymbolgene, null
155255689pawr.SAfrican Clawed Frogsymbolgene, null
16566047AC138894.3PRKC, apoptosis, WT1, regulator (PAWR) pseudogeneHumannamegene, processed_pseudogene
7250955PAWRP2pro-apoptotic WT1 regulator pseudogene 2162874996228750595Humansymbol , old_gene_name , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
7255810PAWRP1pro-apoptotic WT1 regulator pseudogene 1109518364895184219Humansymbol , COSMIC , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1316870THAP1THAP domain containing 1The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links ... (more)84283667442843325Human181descriptiongene, protein-coding, REVIEWED [RefSeq]