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24 records found for search term Parl
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
1306191Parlpresenilin associated, rhomboid-likeENCODES a protein that exhibits endopeptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN neuron differentiation; response to nutrient levels; membrane protein proteolysis (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH Insulin Resista119409755994124915Rat114symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1314669PARLpresenilin associated rhomboid likeThis gene encodes a member of the rhomboid family of intramembrane serine proteases that is localized to the inner mitochondrial membrane. The encoded protein regulates mitochondrial remodeling and apoptosis through regulated substrate proteolysis. Proteolytic processing of the encoded protein resul3183826489183884880Human108symbol , old_gene_name , COSMIC , Human Proteome Mapgene, protein-coding, REVIEWED [RefSeq]
1550418Parlpresenilin associated, rhomboid-likeEnables endopeptidase activity. Involved in several processes, including mitochondrial fusion; negative regulation of apoptotic signaling pathway; and regulation of mitophagy. Located in mitochondrial inner membrane. Used to study Leigh disease. Human ortholog(s) of this gene implicated in Leber her162009857020121090Mouse156symbol , old_gene_name , PhenoGen , descriptiongene, protein-coding, VALIDATED [RefSeq]
8980497Parlpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN membrane protein proteolysis (ortholog); mitochondrial fusion (ortholog); negative regulation of intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN mitochondriNW_0049554202354912523581782Chinchilla45symbolgene, protein-coding, MODEL [RefSeq]
11774734PARLpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (inferred); hydrolase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN neuron differentiation (ortholog); response to nutrient levels (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH bre3180862434180921197Bonobo40symbolgene, protein-coding, MODEL [RefSeq]
12434421PARLpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (inferred); hydrolase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN neuron differentiation (ortholog); response to nutrient levels (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH bre341679004916837557Dog43symbolgene, protein-coding, MODEL [RefSeq]
12682213Parlpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (inferred); hydrolase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN neuron differentiation (ortholog); response to nutrient levels (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH breNW_00493657859457655992972Squirrel40symbolgene, protein-coding, MODEL [RefSeq]
18910633Parlpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (ortholog); INVOLVED IN membrane protein proteolysis (ortholog); mitochondrial fusion (ortholog); negative regulation of intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH breast caNaked Mole-Rat47symbolgene, protein-coding, MODEL [RefSeq]
14124498PARLpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (inferred); hydrolase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN neuron differentiation (ortholog); response to nutrient levels (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH brePig44symbolgene, protein-coding, MODEL [RefSeq]
329329189parlTropical Clawed Frogsymbolgene, null
18794301PARLpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (inferred); hydrolase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN neuron differentiation (ortholog); response to nutrient levels (ortholog); PARTICIPATES IN mitochondrial autophagy pathway; ASSOCIATED WITH breGreen Monkey40symbolgene, protein-coding, MODEL [RefSeq]
626165276Parlpresenilin associated rhomboid likeENCODES a protein that exhibits endopeptidase activity (ortholog); serine-type endopeptidase activity (ortholog); INVOLVED IN membrane protein proteolysis (ortholog); mitochondrial fusion (ortholog); negative regulation of intrinsic apoptotic signaling pathway (ortholog); PARTICIPATES IN mitochondriBlack Rat45symbolgene, protein-coding, MODEL [RefSeq]
329329188parl.LAfrican Clawed Frogsymbolgene, null
1593335Parl-ps1presenilin associated, rhomboid-like, pseudogene 11193397821193447232Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
2320517Parl-ps2presenilin associated, rhomboid-like, pseudogene 2X104421492104423129Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
41064515Parl-ps3presenilin associated, rhomboid-like, pseudogene 3X104134802104136332Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
41398432Parl-ps4presenilin associated, rhomboid-like, pseudogene 4X104174180104185076Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
41296444Parl-ps5presenilin associated, rhomboid-like, pseudogene 5X104696134104702544Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
41070429Parl-ps6presenilin associated, rhomboid-like, pseudogene 6X104115638104116698Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
6494941Parl-ps7presenilin associated, rhomboid-like, pseudogene 763950069639501781Ratsymbol , PhenoGengene, pseudo, MODEL [RefSeq]
16557287PARLP1PARL pseudogene 13120028713120030058Humansymbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
16552308PARLP2PARL pseudogene 2INTERACTS WITH okadaic acid6143342239143343577Human1symbol , old_gene_name , COSMIC , name , Human Proteome Mapgene, pseudo, INFERRED [RefSeq]
1617904BC065397cDNA sequence BC065397X135643706135704113Mouse3old_gene_symbolgene, ncrna, VALIDATED [RefSeq]
8699373LINC01269long intergenic non-protein coding RNA 1269INTERACTS WITH 2-hydroxypropanoic acid; aristolochic acid A; lipopolysaccharide147069869870712153Human8old_gene_symbolgene, ncrna, VALIDATED [RefSeq]