| 1305606 | Otud4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); K63-linked deubiquitinase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); DNA alkylation repair (ortholog); negative regulation of interleukin-1-medi ated signaling pathway (ortholog); ASSOCIATED WITH amenorrhea (ortholog); FOUND IN cytosol (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 19 | 45141043 | 45184136 | Rat | 94 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1313734 | Otud4 | OTU domain containing 4 | Enables K63-linked deubiquitinase activity. Involved in negative regulation of interleukin-1-mediated signaling pathway; negative regulation of toll-like receptor signaling pathway; and protein K63-linked deubiquitination. Predicted to be located in cytosol. Is expressed in several structures, inclu ding brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system. Orthologous to human OTUD4 (OTU deubiquitinase 4). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 80366305 | 80404384 | Mouse | 124 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1603307 | OTUD4 | OTU deubiquitinase 4 | Alternatively spliced transcript variants have been found for this gene. The smaller protein isoform encoded by the shorter transcript variant is found only in HIV-1 infected cells. [provided by RefSeq, Jul 2010] | 4 | 145133650 | 145180589 | Human | 108 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8738818 | Otud4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); K63-linked deubiquitinase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); DNA alkylation repair (ortholog); negative regulation of interleukin-1-medi ated signaling pathway (ortholog); ASSOCIATED WITH amenorrhea (ortholog); FOUND IN cytosol (ortholog) | NW_004955428 | 1062998 | 1108711 | Chinchilla | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11718952 | OTUD4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); K63-linked deubiquitinase activity (inferred); INVOLVED IN antiviral innate immune response (inferred); DNA alkylation repair (inferred); negative regulation of interleukin- 1-mediated signaling pathway (inferred); ASSOCIATED WITH amenorrhea (ortholog); FOUND IN cytosol (inferred) | 4 | 137480809 | 137527651 | Bonobo | 27 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12104622 | OTUD4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN antiviral innate immune response (inferred); DNA alkylation repair (inferred); immune system process (inferred); ASSOCIATED WITH a menorrhea (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | 15 | 43816656 | 43861813 | Dog | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12731582 | Otud4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); K63-linked deubiquitinase activity (inferred); INVOLVED IN antiviral innate immune response (inferred); DNA alkylation repair (inferred); negative regulation of interleukin- 1-mediated signaling pathway (inferred); ASSOCIATED WITH amenorrhea (ortholog); FOUND IN cytosol (inferred) | NW_004936535 | 3911904 | 3950675 | Squirrel | 25 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 13908478 | OTUD4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN antiviral innate immune response (inferred); DNA alkylation repair (inferred); immune system process (inferred); ASSOCIATED WITH a menorrhea (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred); INTERACTS WITH deoxynivalenol | | | | Pig | 33 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155242760 | otud4 | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18348425 | OTUD4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (inferred); cysteine-type peptidase activity (inferred); hydrolase activity (inferred); INVOLVED IN antiviral innate immune response (inferred); DNA alkylation repair (inferred); immune system process (inferred); ASSOCIATED WITH a menorrhea (ortholog); FOUND IN cytoplasm (inferred); cytosol (inferred); nucleus (inferred) | | | | Green Monkey | 35 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625951381 | Otud4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits cysteine-type deubiquitinase activity (ortholog); K63-linked deubiquitinase activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); DNA alkylation repair (ortholog); negative regulation of interleukin-1-medi ated signaling pathway (ortholog); ASSOCIATED WITH amenorrhea (ortholog); FOUND IN cytosol (ortholog) | | | | Black Rat | 19 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18927613 | Otud4 | OTU deubiquitinase 4 | ENCODES a protein that exhibits molecular adaptor activity (ortholog); INVOLVED IN antiviral innate immune response (ortholog); DNA alkylation repair (ortholog); protein K11-linked deubiquitination (ortholog); ASSOCIATED WITH amenorrhea (ortholog); FOUND IN cytosol (ortholog) | | | | Naked Mole-Rat | 21 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155238037 | otud4.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155242761 | otud4.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 8548154 | OTUD4P1 | OTUD4 pseudogene 1 | | 12 | 3839459 | 3846276 | Human | | symbol , COSMIC , name , Human Proteome Map | gene, pseudo, INFERRED [RefSeq] |