Otc Gene Search Result

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13 records found for search term Otc

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
3236	Otc	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding; identical protein binding; ornithine carbamoyltransferase activity; INVOLVED IN citrulline biosynthetic process; liver development; midgut development; PARTICIPATES IN urea cycle pathway; AGAT deficiency pathway; arginine and proline metabolic path ... (more) way; ASSOCIATED WITH Acidoses; alcohol-associated liver disease; Animal Hepatitis; FOUND IN mitochondrial inner membrane; mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol	X	15126358	15202473	Rat	255	symbol , old_gene_name , PhenoGen	gene, protein-coding, PROVISIONAL [RefSeq]
11039	Otc	ornithine transcarbamylase	Predicted to enable several functions, including identical protein binding activity; ornithine carbamoyltransferase activity; and phosphate ion binding activity. Predicted to be involved in several processes, including ammonium homeostasis; non-proteinogenic amino acid metabolic process; and urea cy ... (more) cle. Located in mitochondrial inner membrane. Is expressed in alimentary system; intestine; intrahepatic bile duct epithelium; liver; and small intestine. Used to study ornithine carbamoyltransferase deficiency. Human ortholog(s) of this gene implicated in ornithine carbamoyltransferase deficiency. Orthologous to human OTC (ornithine transcarbamylase). [provided by Alliance of Genome Resources, Apr 2025]	X	10118584	10187275	Mouse	410	symbol , old_gene_name , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
732939	OTC	ornithine transcarbamylase	This nuclear gene encodes a mitochondrial matrix enzyme. The encoded protein is involved in the urea cycle which functions to detoxify ammonia into urea for excretion. Mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. [provided by RefSeq, May 2022]	X	38327684	38422928	Human	511	symbol , old_gene_name , COSMIC , Human Proteome Map , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
8775465	Otc	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN ammonium homeostasis (ortholog); citrulline biosynthetic process (ortholog); L-ornithine catabolic process (ortholog); PARTICIPATES IN ... (more) AGAT deficiency pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)	NW_004955601	481524	543176	Chinchilla	64	symbol	gene, protein-coding, MODEL [RefSeq]
11868874	OTC	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); liver development (ortholog); midgut development (ortholog); PARTICIPATES IN AGAT deficienc ... (more) y pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog)	X	30796828	30868144	Bonobo	81	symbol	gene, protein-coding, MODEL [RefSeq]
12341549	OTC	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); liver development (ortholog); midgut development (ortholog); PARTICIPATES IN AGAT deficienc ... (more) y pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog)	X	33130921	33200441	Dog	82	symbol	gene, protein-coding, MODEL [RefSeq]
12562252	Otc	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); liver development (ortholog); midgut development (ortholog); PARTICIPATES IN AGAT deficienc ... (more) y pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog)	NW_004936502	5234253	5291891	Squirrel	81	symbol	gene, protein-coding, MODEL [RefSeq]
155237247	otc						Tropical Clawed Frog		symbol	gene, null
18925332	Otc	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); liver development (ortholog); midgut development (ortholog); PARTICIPATES IN AGAT deficienc ... (more) y pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog)				Naked Mole-Rat	81	symbol	gene, protein-coding, MODEL [RefSeq]
625999852	Otc	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN ammonium homeostasis (ortholog); citrulline biosynthetic process (ortholog); L-ornithine catabolic process (ortholog); PARTICIPATES IN ... (more) AGAT deficiency pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)				Black Rat	64	symbol	gene, protein-coding, MODEL [RefSeq]
14195640	OTC	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); liver development (ortholog); midgut development (ortholog); PARTICIPATES IN AGAT deficienc ... (more) y pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog); mitochondrion (ortholog)				Pig	86	symbol , old_gene_name	gene, protein-coding, PROVISIONAL [RefSeq]
18533324	OTC	ornithine transcarbamylase	ENCODES a protein that exhibits amino acid binding (ortholog); identical protein binding (ortholog); ornithine carbamoyltransferase activity (ortholog); INVOLVED IN citrulline biosynthetic process (ortholog); liver development (ortholog); midgut development (ortholog); PARTICIPATES IN AGAT deficienc ... (more) y pathway; arginine and proline metabolic pathway; argininosuccinic aciduria pathway; ASSOCIATED WITH Acidoses (ortholog); alcohol-associated liver disease (ortholog); Animal Hepatitis (ortholog); FOUND IN mitochondrial inner membrane (ortholog)				Green Monkey	81	symbol	gene, protein-coding, MODEL [RefSeq]
155257087	otc.S						African Clawed Frog		symbol	gene, null