| 1343355 | NKRF | NFKB repressing factor | This gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cy toplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010] | X | 119588337 | 119606424 | Human | 74 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 1619934 | Nkrf | NF-kappaB repressing factor | Predicted to enable ATPase activator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of DNA-templated transcription and positive reg ulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be active in nucleolus and nucleoplasm. Is expressed in limb mesenchyme and ureter. Orthologous to human NKRF (NFKB repressing factor). [provided by Alliance of Genome Resources, Jul 2025] | X | 36149644 | 36167118 | Mouse | 72 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 6500424 | Nkrf | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; amphetamine; bisphenol A | X | 120992038 | 121010251 | Rat | 74 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 8938768 | Nkrf | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog) | NW_004955534 | 393963 | 408636 | Chinchilla | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11825541 | NKRF | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); positi ve regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | X | 108620903 | 108639027 | Bonobo | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12248864 | NKRF | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); positi ve regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | X | 91621255 | 91639202 | Dog | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12579118 | Nkrf | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); positi ve regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | NW_004936479 | 10312061 | 10327970 | Squirrel | 23 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18683295 | NKRF | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); positi ve regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Green Monkey | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18899919 | Nkrf | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); positi ve regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred) | | | | Naked Mole-Rat | 24 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 39131345 | NKRF | NFKB repressing factor | | | | | Chinchilla | | symbol | gene, protein-coding |
| 626120398 | Nkrf | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of DNA-templated transcription (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); FOUND IN nucleolus (ortholog); nucleus (ortholog) | | | | Black Rat | 14 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 155236447 | nkrf | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 14152215 | NKRF | NFKB repressing factor | ENCODES a protein that exhibits ATPase activator activity (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN DNA-templated transcription (inferred); negative regulation of DNA-templated transcription (inferred); positi ve regulation of transcription by RNA polymerase II (inferred); FOUND IN nucleolus (inferred); nucleoplasm (inferred); nucleus (inferred); INTERACTS WITH cadmium atom; cadmium dichloride; deoxynivalenol | | | | Pig | 27 | symbol , old_gene_symbol | gene, protein-coding, MODEL [RefSeq] |
| 155252952 | nkrf.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 155236448 | nkrf.S | | | | | | African Clawed Frog | | symbol | gene, null |