| 708354 | Nexn | nexilin (F actin binding protein) | ENCODES a protein that exhibits actin filament binding; structural constituent of muscle (ortholog); INVOLVED IN regulation of cell migration (ortholog); regulation of cytoskeleton organization (ortholog); response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cell-substrate junction; focal adhesion; Z disc; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran | 2 | 243846736 | 243878268 | Rat | 176 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1331922 | Nexn | nexilin | Predicted to enable actin filament binding activity and cell-cell adhesion mediator activity. Predicted to be a structural constituent of muscle. Acts upstream of or within response to bacterium. Predicted to be located in actin cytoskeleton and cell-substrate junction. Predicted to be active in sev eral cellular components, including Z disc; axon; and focal adhesion. Is expressed in diaphragm; gut; head mesenchyme; heart; and vertebral axis musculature. Used to study dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1CC and hypertrophic cardiomyopathy 20. Orthologous to human NEXN (nexilin F-actin binding protein). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 151942619 | 151972000 | Mouse | 199 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1354261 | NEXN | nexilin F-actin binding protein | This gene encodes a filamentous actin-binding protein that may function in cell adhesion and migration. Mutations in this gene have been associated with dilated cardiomyopathy, also known as CMD1CC. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010] | 1 | 77888624 | 77943895 | Human | 474 | symbol , COSMIC , Human Proteome Map | gene, protein-coding, REVIEWED [RefSeq] |
| 8896477 | Nexn | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN regulation of cell migration (ortholog); regulation of cytoskeleton organization (ortholog); response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); conges tive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN actin cytoskeleton (ortholog); cell-substrate junction (ortholog); focal adhesion (ortholog) | NW_004955423 | 15278526 | 15299654 | Chinchilla | 30 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 11745855 | NEXN | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cell-substrate junction (ortholog); focal adhesion (ortholog) | 1 | 77104269 | 77162517 | Bonobo | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12285461 | NEXN | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cell-substrate junction (ortholog); focal adhesion (ortholog) | 6 | 68963953 | 69014874 | Dog | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 12572159 | Nexn | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cell-substrate junction (ortholog); focal adhesion (ortholog) | NW_004936571 | 4704009 | 4728305 | Squirrel | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 285316449 | nexn | | | | | | Tropical Clawed Frog | | symbol | gene, null |
| 18927385 | Nexn | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN regulation of cell migration (ortholog); regulation of cytoskeleton organization (ortholog); response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); conges tive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN actin cytoskeleton (ortholog); cell-substrate junction (ortholog); focal adhesion (ortholog) | | | | Naked Mole-Rat | 32 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 18445359 | NEXN | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cell-substrate junction (ortholog); focal adhesion (ortholog) | | | | Green Monkey | 34 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 625958518 | Nexn | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); structural constituent of muscle (ortholog); INVOLVED IN regulation of cell migration (ortholog); regulation of cytoskeleton organization (ortholog); response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); conges tive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN actin cytoskeleton (ortholog); cell-substrate junction (ortholog); focal adhesion (ortholog) | | | | Black Rat | 28 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 14082879 | NEXN | nexilin F-actin binding protein | ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); congestive heart failure (ortholog); dilated cardiomyopathy (ortholog); FOUND IN cell-substrate junction (ortholog); focal adhesion (ortholog); INTERACTS WITH deoxynivalenol | | | | Pig | 42 | symbol | gene, protein-coding, MODEL [RefSeq] |
| 288056949 | nexn.L | | | | | | African Clawed Frog | | symbol | gene, null |
| 285316860 | nexn.S | | | | | | African Clawed Frog | | symbol | gene, null |
| 7246569 | NEXN-AS1 | NEXN antisense RNA 1 | INTERACTS WITH (-)-epigallocatechin 3-gallate; antirheumatic drug; beauvericin | 1 | 77881348 | 77889539 | Human | 16 | symbol , COSMIC , name , Human Proteome Map | gene, ncrna, VALIDATED [RefSeq] |
| 12025699 | LOC106634987 | putative uncharacterized protein NEXN-AS1 | | 1 | 77104763 | 77105644 | Bonobo | | name | gene, protein-coding, MODEL [RefSeq] |
| 598135116 | LOC140709223 | putative uncharacterized protein NEXN-AS1 | | | | | Green Monkey | | name | gene, pseudo, MODEL [RefSeq] |
| 12083912 | MIGA1 | mitoguardin 1 | ENCODES a protein that exhibits protein heterodimerization activity (ortholog); protein homodimerization activity (ortholog); INVOLVED IN mitochondrial fusion (inferred); FOUND IN plasma membrane (ortholog) | 6 | 69019898 | 69107024 | Dog | 14 | ensembl_gene_symbol | gene, protein-coding, MODEL [RefSeq] |