NEXN (nexilin F-actin binding protein) - Rat Genome Database

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Gene: NEXN (nexilin F-actin binding protein) Pan paniscus
Analyze
Symbol: NEXN
Name: nexilin F-actin binding protein
RGD ID: 11745855
Description: ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN response to bacterium (ortholog); ASSOCIATED WITH cardiomyopathy (ortholog); dilated cardiomyopathy (ortholog); dilated cardiomyopathy 1A (ortholog); FOUND IN cell-substrate junction (ortholog); focal adhesion (ortholog); Z disc (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: nexilin
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21148,945,882 - 149,003,523 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,104,269 - 77,162,517 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,187,779 - 79,247,161 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,187,779 - 79,244,732 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NEXN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21148,945,882 - 149,003,523 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0177,104,269 - 77,162,517 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1179,187,779 - 79,247,161 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl179,187,779 - 79,244,732 (+)Ensemblpanpan1.1panPan2
NEXN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38177,888,624 - 77,943,895 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl177,888,513 - 77,943,895 (+)EnsemblGRCh38hg38GRCh38
GRCh37178,354,309 - 78,409,580 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36178,126,788 - 78,182,168 (+)NCBINCBI36Build 36hg18NCBI36
Build 34178,095,828 - 78,120,930NCBI
Celera176,593,252 - 76,648,659 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef176,485,827 - 76,541,199 (+)NCBIHuRef
CHM1_1178,470,589 - 78,525,920 (+)NCBICHM1_1
T2T-CHM13v2.0177,727,428 - 77,782,694 (+)NCBIT2T-CHM13v2.0
Nexn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393151,942,619 - 151,972,000 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3151,942,619 - 151,971,987 (-)EnsemblGRCm39 Ensembl
GRCm383152,236,982 - 152,266,350 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3152,236,982 - 152,266,350 (-)EnsemblGRCm38mm10GRCm38
MGSCv373151,899,946 - 151,929,284 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363152,174,368 - 152,216,670 (-)NCBIMGSCv36mm8
Celera3158,714,841 - 158,744,187 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map377.07NCBI
Nexn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82243,846,736 - 243,878,268 (-)NCBIGRCr8
mRatBN7.22241,186,783 - 241,218,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2241,186,790 - 241,218,342 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2249,001,122 - 249,021,940 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02246,888,139 - 246,908,957 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02241,787,531 - 241,808,345 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02257,452,937 - 257,484,607 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2257,453,347 - 257,484,587 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02276,129,684 - 276,161,434 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42250,762,017 - 250,783,765 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12250,776,623 - 250,798,372 (-)NCBI
Celera2233,122,059 - 233,142,757 (-)NCBICelera
Cytogenetic Map2q45NCBI
Nexn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542315,278,526 - 15,299,659 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542315,278,526 - 15,299,654 (-)NCBIChiLan1.0ChiLan1.0
NEXN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1668,963,953 - 69,014,874 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl668,964,187 - 69,107,009 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha671,621,447 - 71,672,401 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0669,548,680 - 69,599,798 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl669,549,074 - 69,597,504 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1669,055,004 - 69,106,149 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0669,000,304 - 69,051,252 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0669,486,699 - 69,537,684 (-)NCBIUU_Cfam_GSD_1.0
Nexn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505889,191,107 - 89,217,953 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365714,703,955 - 4,729,018 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365714,704,009 - 4,728,305 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NEXN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6135,318,754 - 135,382,882 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16135,315,000 - 135,382,911 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26125,500,984 - 125,502,455 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NEXN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12055,229,093 - 55,286,703 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2055,234,782 - 55,285,755 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603362,227,938 - 62,283,369 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nexn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474219,313,264 - 19,349,394 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474219,313,262 - 19,357,052 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000039389   ⟹   ENSPPAP00000016691
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl179,187,779 - 79,244,732 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000039395   ⟹   ENSPPAP00000016697
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl179,187,779 - 79,244,732 (+)Ensembl
RefSeq Acc Id: XM_003807779   ⟹   XP_003807827
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,515 (-)NCBI
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBI
Mhudiblu_PPA_v0177,104,836 - 77,162,517 (+)NCBI
PanPan1.1179,187,892 - 79,247,161 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008959912   ⟹   XP_008958160
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,477 (-)NCBI
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBI
Mhudiblu_PPA_v0177,104,832 - 77,162,439 (+)NCBI
PanPan1.1179,187,784 - 79,244,732 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008959914   ⟹   XP_008958162
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,523 (-)NCBI
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBI
Mhudiblu_PPA_v0177,104,269 - 77,162,514 (+)NCBI
PanPan1.1179,187,779 - 79,244,732 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034928926   ⟹   XP_034784817
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,515 (-)NCBI
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBI
Mhudiblu_PPA_v0177,104,854 - 77,161,840 (+)NCBI
RefSeq Acc Id: XM_034928937   ⟹   XP_034784828
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,513 (-)NCBI
NHGRI_mPanPan11148,107,166 - 148,166,147 (-)NCBI
Mhudiblu_PPA_v0177,104,807 - 77,161,840 (+)NCBI
RefSeq Acc Id: XM_063607187   ⟹   XP_063463257
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 148,975,354 (-)NCBI
RefSeq Acc Id: XM_063607189   ⟹   XP_063463259
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,477 (-)NCBI
RefSeq Acc Id: XM_063607190   ⟹   XP_063463260
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21148,945,882 - 149,003,477 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_008958160   ⟸   XM_008959912
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AH68 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008958162   ⟸   XM_008959914
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AH72 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003807827   ⟸   XM_003807779
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_034784828   ⟸   XM_034928937
- Peptide Label: isoform X5
RefSeq Acc Id: XP_034784817   ⟸   XM_034928926
- Peptide Label: isoform X8
RefSeq Acc Id: ENSPPAP00000016697   ⟸   ENSPPAT00000039395
RefSeq Acc Id: ENSPPAP00000016691   ⟸   ENSPPAT00000039389
RefSeq Acc Id: XP_063463260   ⟸   XM_063607190
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063463259   ⟸   XM_063607189
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063463257   ⟸   XM_063607187
- Peptide Label: isoform X2
Protein Domains
Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000031451 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000039389.1 UniProtKB/TrEMBL
  ENSPPAT00000039395.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
NCBI Gene NEXN ENTREZGENE
PANTHER MITOGUARDIN UniProtKB/TrEMBL
  MITOGUARDIN 2 UniProtKB/TrEMBL
Pfam I-set UniProtKB/TrEMBL
PROSITE IG_LIKE UniProtKB/TrEMBL
SMART SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
UniProt A0A2R9AH68 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AH72 ENTREZGENE, UniProtKB/TrEMBL